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Study on antigenic analysis and serial antibody titration by using leptospira interrogans isolated at Chungchongbukdo

Park KH, Hong SC, Chang WH

  • KMID: 1687909
  • J Korean Soc Microbiol.
  • 1991 Aug;26(4):317-327.
No abstract available.
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Identification of new serovar yeonchon and hongchon belonging to leptospira interrogans icterohaemorrhagiae serogroup

Oh HB, Chang WH, Cho MK, Seong WK, Park KS

  • KMID: 1687903
  • J Korean Soc Microbiol.
  • 1991 Jun;26(3):253-262.
No abstract available.
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Prevalence of Leptospira interrogans in Wild Rodents in Korea

Cho MH, Kee SH, Kim YJ, Kim YW, Song HJ, Song KJ, Kim HH, Oh HB

  • KMID: 2099319
  • J Korean Soc Microbiol.
  • 1999 Dec;34(6):591-594.
Leptospirosis has been known as endemic disease in Korea since 1984. Wild rodent, mostly Apodemus agrarius, has been known as an important source of leptospiral infection especially in rainy circumstances...
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Development of a multiplex PCR to identify Salmonella, Leptospira and Brucella species in tissue samples

Lam TQ, Yoon BI, Hahn TW

  • KMID: 1435817
  • Korean J Vet Res.
  • 2012 Jun;52(2):75-82.
We have developed and optimized a multiplex polymerase chain reaction (mPCR) for simultaneous detection of Brucella, Salmonella and Leptospira with high sensitivity and specificity. Three pairs of oligonucleotide primers were...
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Effects of Addition of Sugars on the Stability of Leptospira Vaccine

Seong I

  • KMID: 2082914
  • Korean J Infect Dis.
  • 1998 Dec;30(6):551-557.
BACKGROUND: Most of the current licensed viral and bacterial vaccines produced in the world are in the state of antigen suspension, and the immunogenicities of the vaccines can be maintained...
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Identification of Leptospira species of Korean Isolates using Phylogenetic Analysis of Polymerase Chain Reaction-amplified 16S rDNA and LipL32 Genes

Park KH, Choi YJ, Shin SH, Choi MK, Kim YW, Jang WJ

In this study, we selected only serologically identified 15 Leptosira interrogans isolates in the past and analyzed and identified them by using molecular method. The partial 16S rDNA and LipL32...
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The C-terminal variable domain of LigB from Leptospira mediates binding to fibronectin

Lin YP, Chang YF

Adhesion through microbial surface components that recognize adhesive matrix molecules is an essential step in infection for most pathogenic bacteria. In this study, we report that LigB interacts with fibronectin...
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Rhabdomyolysis Induced Acute Kidney Injury in a Patient with Leptospirosis

Choi YJ, Park JM, Jung YH, Nam JH, Chung HH, Kim TW, Cho KH, Do JY, Yun KW, Park JW

  • KMID: 2320087
  • Yeungnam Univ J Med.
  • 2011 Jun;28(1):54-59.
Leptospirosis is a spirochetal infectious disease caused by Leptospira interrogans, and may vary in degree from an asymptomatic infection to a severe and fatal illness. The kidney is one of...
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In vitro susceptibilities of Leptospira spp. and Borrelia burgdorferi isolates to amoxicillin, tilmicosin, and enrofloxacin

Kim D, Kordick D, Divers T, Chang YF

Antimicrobial susceptibility testing was conducted with 6 different spirochetal strains (4 strains of Leptospira spp. and 2 strains of Borrelia burgdorferi) against 3 antimicrobial agents, commonly used in equine and...
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Characterization of Korean Leptospira interrogans Isolates by Pulsed-Field Gel Electrophoresis of Not I Digests of DNA

Yim EK, Chang IA, Lee JS, Kim YW, Woo SD, Ahn JY, Park SK, Cho MK

  • KMID: 2170093
  • Infect Chemother.
  • 2004 Apr;36(2):59-67.
BACKGROUND: Many strains of Leptospira interrogans have been isolated in Korea since 1984. Most isolates were identified as serovar lai by serological methods. The pulsed field gel electrophoresis (PFGE) patterns...
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Leptospirosis in the Republic of Korea: Historical Perspectives, Current Status and Future Challenges

Kim MJ

Leptospirosis is an important public health problem in the Republic of Korea (ROK), occurring sporadically or in outbreaks during the autumn season. Wild rodents, Apodemus agrarius, have been mainly involved...
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Comparative analysis of lipopolysaccharide and lipid antigens of Leptospira interrogans serovars

Cho SN, Uhm JR, Kim JD

Lipopolysaccharide (LPS) or glycolipid antigens of Leptospira interrogans have been candidates as serogroup or serotype specific antigen. In this study, therefore, we prepared the LPS and lipid antigens from L....
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Historical Review of Leptospirosis in the Korea (1945 – 2015)

Kim MJ

Leptospirosis is a widespread worldwide zoonosis. Human leptospirosis was first identified in the Korea in 1984 as the cause of “epidemic pulmonary hemorrhagic fever of unknown etiology” that occurred sporadically...
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Evaluation of a Commercial Immuno-Chromatographic Assay Kit for Rapid Detection of IgM Antibodies against Leptospira Antigen in Human Serum

Amran F, Liow YL, Halim NA

Leptospirosis is a febrile zoonotic disease. Routine diagnosis of leptospirosis is based on the detection of specific antibodies with serological tests. The aim of our study was to determine the...
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Clinical Evaluation of Rapid Diagnostic Test Kit Using the Polysaccharide as a Genus-Specific Diagnostic Antigen for Leptospirosis in Korea, Bulgaria, and Argentina

Lee JW, Park S, Kim SH, Christova , Jacob P, Vanasco NB, Kang YM, Woo YJ, Kim MS, Kim YJ, Cho MK, Kim YW

Leptospirosis, a zoonotic disease that is caused by many serovars which are more than 200 in the world, is an emerging worldwide disease. Accurate and rapid diagnostic tests for leptospirosis...
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Evaluation of safety and immunogenicity of a new octavalent inactivated vaccine containing porcine parvovirus, erysipelas, and leptospira

Kim K, Choi JY, Park SJ, Hahn TW

Porcine parvovirus, Erysipelothrix (E.) rhusiopathiae, and Leptospira (L.) interrogans are considered major etiologic agents of reproductive failure in pigs, causing economic loss in the swine industry. In this study, the...
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An epidemiological comparative study on diagnosis of rodent leptospirosis in Mazandaran Province, northern Iran

Esfandiari B, Pourshafie MR, Gouya MM, Khaki P, Mostafavi , Darvish J, Bidhendi S, Hanifi H, Nahrevanian H

OBJECTIVES: Leptospirosis is a zoonosis caused by leptospires, in which transmission occurs through contact with contaminated biological fluids from infected animals. Rodents can act as a source of infection for...
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A Prospective Multicenter Study of the Etiological Analysis in Adults with Community-Acquired Pneumonia: Legionella, Leptospira, Hantaan virus and Orientia tsutsugamushi

Kim MJ, Cheong HJ, Sohn JW, Shim HS, Park DW, Park SC, Woo JH, Kang JM, Kim YK, Shin WS, Kim YR, Lee HJ, Kim JH

  • KMID: 1599896
  • Korean J Infect Dis.
  • 2001 Feb;33(1):24-31.
BACKGROUND: Despite rigorous investigations, the etiology of community-acquired pneumonia remains unknown in about 50% of hospitalized patients. The diagnosis of the etiological agent is becoming more challenging and more critical...
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Pharmacokinetics of enrofloxacin HCl-2Hâ‚‚O (Enro-C) in dogs and pharmacokinetic/pharmacodynamic Monte Carlo simulations against Leptospira spp.

Sumano H, Ocampo L, Tapia G, Mendoza CD, Gutierrez

Pharmacokinetic/pharmacodynamic (PK/PD) ratios of reference enrofloxacin (Enro-R) and enrofloxacin as HCl-2H₂O (Enro-C), as well as Monte Carlo simulations based on composite MIC₅₀ and MIC₉₀ (MIC, minimum inhibitory concentration) vs. Leptospira...
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Paraplegia in Leptospirosis

Lee HJ, Yang JW, Oh SH, Kim WK

  • KMID: 2065470
  • J Korean Neurol Assoc.
  • 2000 Sep;18(5):676-678.
Leptospirosis is an acute generalized infectious disease caused by spirochetes of the genus Leptospira. The clinical forms of leptospirosis in Korea include asymptomatic form, influenza like form, pulmonary form, hepatic...
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