- Essential Elements for Establishing Clinical Next-generation Sequencing Testing
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Park KJ, Lee W, Chun S, Min WK
- KMID: 2441822
- Lab Med Online.
- 2019 Apr;9(2):37-44.
- doi: 10.3343/lmo.2019.9.2.37
Over the past decade, next-generation sequencing (NGS) has evolved at an astonishing pace and has revolutionized clinical medicine as well as genomics research. The rapid advancements in NGS technologies have... -
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- A Case of Urinary Tract Infection Caused by the Emerging Uropathogen Actinotignum schaalii
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Kwon WK, Song DJ, Huh HJ, Park SH, Ki CS, Lee NY
- KMID: 2441830
- Lab Med Online.
- 2019 Apr;9(2):94-98.
- doi: 10.3343/lmo.2019.9.2.94
Actinotignum schaalii is an emerging uropathogen; however, routine culture protocols and usual phenotypic methods do not allow for easy detection and identification. Herein, we report the first Korean case of... -
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- A Case of Mature B-cell Neoplasm with Light Chain Clonality Confirmed by Cytoplasmic Light Chain Expression Using Flow Cytometry
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Cho EH, Yoo IY, Ryu MR, Shin HY, Kim SH, Cho D
- KMID: 2441831
- Lab Med Online.
- 2019 Apr;9(2):99-102.
- doi: 10.3343/lmo.2019.9.2.99
Surface immunoglobulin light-chain restriction is evidence of clonality in mature B-cell neoplasms. An aberrant pattern of surface light-chain expression can also be considered evidence of clonality. However, because this result... -
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- A Report of Bone Marrow Metastasis of Colon Cancer as a Primary Diagnosis, Supported by Cytokeratin Immunohistochemical Staining
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Kim B, Lee KT
- KMID: 2441832
- Lab Med Online.
- 2019 Apr;9(2):103-106.
- doi: 10.3343/lmo.2019.9.2.103
Bone marrow metastasis of colon cancer is rare. Here, we report a 56-year-old female patient who presented with pancytopenia. She was diagnosed with colon cancer accompanied by lung and axial... -
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- Performance Evaluation of Two Immunochromatographic Assays for Rotavirus Detection in Stool Specimens
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Kim S, Kim YJ, Cho SY, Park TS, Lee HJ
- KMID: 2441826
- Lab Med Online.
- 2019 Apr;9(2):73-76.
- doi: 10.3343/lmo.2019.9.2.73
BACKGROUND: Rotavirus is a major pathogen causing enteritis worldwide in children under five years of age. In recent years, immunochromatographic assay (ICA) has been widely used as a diagnostic test... -
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- A Case of Fungemia with Co-isolation of Candida parapsilosis and Trichosporon asahii Confirmed by MALDI-TOF MS and D2 rRNA Sequencing
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Seo JD, Kim NH, Hong YJ, Kim TS, Hwang SM, Park JS, Seong MW, Park KU, Song J, Park SS, Kim EC
- KMID: 2441829
- Lab Med Online.
- 2019 Apr;9(2):88-93.
- doi: 10.3343/lmo.2019.9.2.88
Fungi are a major cause of human infections with diverse clinical manifestations. The incidence of fungal infections has increased over time, particularly in patients who have risk factors such as... -
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- A Clue to Discovering Unstable Hemoglobin Variants via Abnormal WBC Differential Scattergrams Using the Sysmex Automated Hematology Analyzer
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Park S, Jeong TD, Hong KS, Huh J
- KMID: 2441828
- Lab Med Online.
- 2019 Apr;9(2):84-87.
- doi: 10.3343/lmo.2019.9.2.84
Incidentally, hemoglobin (Hb) variants can be detected using HbA1c tests in clinical laboratories. We found 38 patients with Hb variants after reviewing a total of 29,398 HbA1c test results from... -
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- Comparison between Medion Vacuon Tube and BD Vacutainer Tube for Clinical Laboratory Practice
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Jhang J, Cho JY, Lee JH, Kim J
- KMID: 2441827
- Lab Med Online.
- 2019 Apr;9(2):77-83.
- doi: 10.3343/lmo.2019.9.2.77
BACKGROUND: Most of the blood-test samples are collected and carried in vacuum tubes. We have compared a newly developed vacuum tube, ‘Vacuon’ (Medion, Korea) and ‘BD Vacutainer®’ (BD, USA) in... -
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- Two Cases of Hypersensitivity Reactions Caused by Human Serum Albumin During Therapeutic Plasma Exchange
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Kim TY, Shin DW, Hong YJ, Kim H, Park KU, Han KS
- KMID: 2441833
- Lab Med Online.
- 2019 Apr;9(2):107-112.
- doi: 10.3343/lmo.2019.9.2.107
Iso-oncotic human serum albumin (HSA) is the primary replacement fluid of choice during therapeutic plasma exchange (TPE). Hypersensitivity reactions to HSA are rare, but require proper evaluation and management. In... -
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- Evaluation of Time and Temperature Stability of Paroxysmal Nocturnal Hemoglobinuria Cells by Flow Cytometry
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Lee SH, Bang HI, Shin YJ, Shin WY, Kim J, Park R, Shin JW, Choi TY
- KMID: 2441824
- Lab Med Online.
- 2019 Apr;9(2):57-62.
- doi: 10.3343/lmo.2019.9.2.57
BACKGROUND: Flow cytometry analysis of paroxysmal nocturnal hemoglobinuria (PNH) is significantly affected by the methodology used. The lack of data on the effect of age and refrigeration on PNH clone... -
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- Effects of Pre-analytical Variables on Cell-free DNA Extraction for Liquid Biopsy
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Jeong TD, Kim MH, Park S, Chung HS, Lee JW, Chang JH, Huh J
- KMID: 2441823
- Lab Med Online.
- 2019 Apr;9(2):45-56.
- doi: 10.3343/lmo.2019.9.2.45
BACKGROUND: Extraction of cell-free DNA (cfDNA) is a key step for determining the quality of cfDNA-related molecular diagnostics. We evaluated the effect of sample containers and sample storage conditions on... -
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- Trends in Bloodstream Infections and Antimicrobial Susceptibilities at a University Hospital in Korea Between 2007 and 2016
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Lim S, Yeom JS, Joo EJ, Cheong HS, Lee K, Woo HY, Park H, Kwon MJ
- KMID: 2441825
- Lab Med Online.
- 2019 Apr;9(2):63-72.
- doi: 10.3343/lmo.2019.9.2.63
BACKGROUND: Blood culture is an important method for identifying infectious microorganisms and confirming that a selected antimicrobial treatment is appropriate. In this study, we investigated the annual changes in the... -
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