Lab Med Online.  2019 Apr;9(2):94-98. 10.3343/lmo.2019.9.2.94.

A Case of Urinary Tract Infection Caused by the Emerging Uropathogen Actinotignum schaalii

• Kwon WK
• Song DJ
• Huh HJ
• Park SH
• Ki CS
• Lee NY

• KMID: 2441830
• DOI: http://doi.org/10.3343/lmo.2019.9.2.94

Abstract

Actinotignum schaalii is an emerging uropathogen; however, routine culture protocols and usual phenotypic methods do not allow for easy detection and identification. Herein, we report the first Korean case of urinary tract infection caused by A. schaalii in a 79-year-old patient with prostate cancer. A gram-positive rod bacterium was isolated from the patient's urine after 2 days of culture and identified as A. schaalii using matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry and DNA target sequencing.

Keyword

Actinotignum schaalii; Uropathogen; DNA target sequencing; MALDI-TOF

MeSH Terms

Aged
DNA
Humans
Mass Spectrometry
Prostatic Neoplasms
Urinary Tract Infections*
Urinary Tract*
DNA

Figure

• 

  Fig. 1 (A) Pinpoint, whitish to gray colonies on a blood agar plate at two days of culture. (B) Microscopic morphology of Actinotignum schaalii (Gram stain, ×1,000).

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  Fig. 2 Neighbor-joining phylogenetic tree showing the relationships of A. schaalii and other Actinomyces species. Reference sequences are from species type strains; GenBank accession numbers are given in parentheses.

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