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Performance Evaluation of the Beckman Coulter DxN VERIS Hepatitis B Virus (HBV) Assay in Comparison With the Abbott RealTime HBV Assay

Park J, Cho H, Choi SJ, Lee GD, Sin SH, Ryu JH, Park HS, Lee H, Kim Y, Oh EJ

The detection and quantification of hepatitis B virus (HBV) DNA plays an important role in diagnosing and monitoring HBV infection as well as in assessing the therapeutic response. We compared...
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Survey and Solutions for the Current Status of Quality Control in Small Hospital Laboratories

Kim JH, Choi EJ, Hwang G, Lee JH, Han MS

BACKGROUND: To prevent medically significant errors, hospital laboratories must perform thorough statistical quality control (QC) procedures. We surveyed the QC status of small laboratories and created new statistical QC software...
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Removing Lipemia in Serum/Plasma Samples: A Multicenter Study

Castro-Castro MJ, Candás-Estébanez B, Esteban-Salán M, Calmarza P, Arrobas-Velilla T, Romero-Román C, Pocoví-Mieras M, Aguilar-Doreste JA, on behalf of the Commission on Lipoprotein and Vascular Diseases, Sociedad Española de Química Clínica

BACKGROUND: Lipemia, a significant source of analytical errors in clinical laboratory settings, should be removed prior to measuring biochemical parameters. We investigated whether lipemia in serum/plasma samples can be removed...
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Clinical Pharmacogenetic Testing and Application: Laboratory Medicine Clinical Practice Guidelines

Kim S, Yun YM, Chae HJ, Cho HJ, Ji M, Kim IS, Wee KA, Lee W, Song SH, Woo HI, Lee SY, Chun S

Pharmacogenetic testing for clinical applications is steadily increasing. Correct and adequate use of pharmacogenetic tests is important to reduce unnecessary medical costs and adverse patient outcomes. This document contains recommended...
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Development of a Novel Quality Improvement Indicator Based on the Hemolysis Index

Lee EJ, Kim M, Kim HS, Park MJ, Lee YK, Kang HJ

Hemolysis frequently causes preanalytical errors in laboratory measurements. We aimed to develop a quality improvement indicator for evaluating the extent of inappropriate procedures causing hemolysis in clinical samples collected in...
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Current Pathological and Laboratory Considerations in the Diagnosis of Disseminated Intravascular Coagulation

Toh CH, Alhamdi Y, Abrams ST

Systemically sustained thrombin generation in vivo is the hallmark of disseminated intravascular coagulation (DIC). Typically, this is in response to a progressing disease state that is associated with significant cellular...
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A Nationwide Multicenter Survey for Mycobacterial Testing in Korea

Song SA, Kim SH, Kim CK, Sung H, Kim S, Chang CL, Shin JH

BACKGROUND: There have been steady changes and improvements in diagnostic tests for Mycobacterium tuberculosis, so it is necessary to carry out periodic surveys to understand the current situation. The aims...
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Sensitization patterns to common allergens in Korean children younger than 6 years of age presenting with typical symptoms or signs of allergic diseases: a single center study

Yoon JW, Lee SM, Kim JH, Kim NY, Baek JH, Baek HS, Jee HM, Kim HY, Choi SH, Kim KE, Yum HY, Han MY, Kim J, Shin YH

PURPOSE: Population studies have reported that sensitization to inhalant allergens is rare in young children; however, most subjects in those studies had little or no symptoms or signs highly suggestive...
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Molecular Characteristics of blaOXA-23-Producing Acinetobacter baumannii Isolated from a University Hospital

Jang IH, Park SD, Uh Y, Lee GS, Kim JB, Choi I

BACKGROUND: Multi-drug resistant (MDR) Acinetobacter baumannii has emerged as a significant infectious agent in hospitals worldwide. The purpose of this study was to determine the molecular characterization of MDR A....
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Development of a Document Management System for the Standardization of Clinical Laboratory Documents

Hwang SH, Jung SK, Kang SJ, Cha HS, Chung SH, Lee DH

BACKGROUND: Documentation is very important; a considerable number of documents exist for use in accreditation inspection. However, most laboratories do not effectively manage the processes of documentation, organization, and storage....
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Analysis of Factors Influencing the Generation of Unqualified Clinical Samples and Measures to Prevent this Generation

Lai X, Yang P, Zhang Y, Cao J, Zhang L

BACKGROUND: We investigated the influence of pre-analytical factors on the results of clinical tests and thereby analyzed approaches to improve quality management in clinical laboratories. METHODS: Unqualified clinical samples were selected...
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Effects of Long Distance Transportation of Specimens on Test Results

Lim HS, Lee YK, Min WK

BACKGROUND: Accuracy of laboratory test results is an important issue. New guidelines for specimen delivery systems are needed for appropriate pretreatment of specimens and accuracy of results. METHODS: We evaluated various...
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Current Status and Proposal of a Guideline for Manual Slide Review of Automated Complete Blood Cell Count and White Blood Cell Dfferential

Woo HY, Shin SY, Park H, Kim YJ, Kim HJ, Lee YK, Chae SL, Chang YH, Choi JR, Han K, Cho SR, Kwon KC

BACKGROUND: Manual slide review (MSR) is usually triggered by the results of automated hematolgy analyzers, but each laboaratory has different ciriteria for MSR. This study was carried out to investigate...
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Comparing Two Diagnostic Laboratory Tests for Several Microdeletions Causing Mental Retardation Syndromes: Multiplex Ligation-Dependent Amplification vs Fluorescent In Situ Hybridization

Cho EH, Park BY, Cho JH, Kang YS

BACKGROUND: Microdeletion syndromes not detectable by conventional cytogenetic analysis have been reported to occur in approximately 5% of patients with unexplained mental retardation (MR). Therefore, it is essential to ensure...
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An Experience of the Use of Anti-HBc and Anti-HBs for Blood Donor Screening Tests at a Tertiary Hospital Blood Center in Korea

Lim YA, Yoon S

BACKGROUND: The aim of this study was to report the first experience of using tests of antibody to hepatitis B core antigen (anti-HBc) and antibody to hepatitis B surface antigen...
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Survey Results of Medical Insurance Reimbursement System for Independent Medical Laboratories in Korea

Bae SY, Kwon JA, Kim JS, Yoon SY, Lee CK, Lee KN, Kim DW, Min WK, Cha YJ, Chae SL, Hwang YS

BACKGROUND: A questionnaire survey was performed to perceive the problem of the current medical insurance reimbursement system for laboratory tests referred to independent medical laboratories; then, we intended to...
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Pseudohyponatremia:Does It Matter in Current Clinical Practice?

Kim GH

Serum consists of water (93% of serum volume) and nonaqueous components, mainly lipids and proteins (7% of serum volume). Sodium is restricted to serum water. In states of hyperproteinemia or...
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Database Conversion and Analysis of Antimicrobial Resistance Profile for Microscan using BacLink 2 Software

Kim JS, Lee YK, Park JY, Kang HJ, Kang SH, Kim YC, Cho HC

  • KMID: 1820202
  • J Lab Med Qual Assur.
  • 2003 Jun;25(1):189-193.
BACKGROUND: In hospital laboratory using Microscan, the search for an isolate or the analysis for antimicrobial susceptibility rates were obtained by the Data Management System (DMS) software. However, it is...
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Laboratory Inspection and Accreditation in Korea II: Analysis of the First Round Inspection

Lee WG, Kwak YS, Lee DH, Hwang YS, Lee KN

  • KMID: 1730148
  • Korean J Lab Med.
  • 2003 Oct;23(5):363-369.
BACKGROUND: The Korean Society of Laboratory Medicine (KSLM) Laboratory Inspection and Accreditation Program (IAP) has been developed after one year of study supported by a research grant from the Ministry...
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Latex Agglutination Test for Differentiating Neonatal Blood from the Maternal Blood in the Meconium

Park IK, Kim DA, Lee WS, Kim TY, Kim CR

  • KMID: 1560317
  • Korean J Lab Med.
  • 2002 Aug;22(4):242-245.
BACKGROUND: The Apt test is used for differentiating neonatal blood from the maternal blood in the meconium. The test requires a sufficient amount of blood to be detectable to the...
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