- Corrigendum: Randomized, crossover questionnaire survey of acceptabilities of controlled-release mesalazine tablets and granules in ulcerative colitis patients
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Yagisawa K, Kobayashi T, Ozaki R, Okabayashi S, Toyonaga T, Miura M, Hayashida M, Saito E, Nakano M, Matsubara H, Hisamatsu T, Hibi T
- KMID: 2504591
- Intest Res.
- 2020 Jul;18(3):343-344.
- doi: 10.5217/ir.2018.00078-c1
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- Parent Artery Complex Coil Protection for Side-Branched Wide-Neck Aneurysms
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Sato K, Aoki H, Jinguji S, Seto H, Kobayashi T
- KMID: 2531568
- Neurointervention.
- 2022 Jul;17(2):115-120.
- doi: 10.5469/neuroint.2022.00136
This study aimed to validate the usefulness of parent artery complex coil protection for the treatment of wide-neck, side-branched, and ruptured aneurysms. A microcatheter was first introduced into the aneurysmal... -
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- De-escalation of Therapy in Patients with Quiescent Inflammatory Bowel Disease
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Miyatani Y, Kobayashi T
- KMID: 2540407
- Gut Liver.
- 2023 Mar;17(2):181-189.
- doi: 10.5009/gnl220070
Inflammatory bowel disease is a chronic disease of unknown origin that requires long-term treatment. The optical duration of maintenance treatment once remission has been achieved remains unclear. When discussing a... -
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- Capsule endoscopy in inflammatory bowel disease: when and how
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Hilmi I, Kobayashi T
- KMID: 2504581
- Intest Res.
- 2020 Jul;18(3):265-274.
- doi: 10.5217/ir.2019.09165
Capsule endoscopy (CE) is emerging as an important investigation in inflammatory bowel disease (IBD); common types include the standard small bowel CE and colon CE. More recently, the pan-enteric CE... -
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- Non-invasive imaging biomarkers for liver steatosis in non-alcoholic fatty liver disease: present and future
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Nogami A, Yoneda M, Iwaki M, Kobayashi T, Honda Y, Ogawa Y, Imajo K, Saito S, Nakajima A
- KMID: 2539795
- Clin Mol Hepatol.
- 2023 Feb;29(Suppl):S123-S135.
- doi: 10.3350/cmh.2022.0357
Non-alcoholic fatty liver disease is currently the most common chronic liver disease, affecting up to 25% of the global population. Simple fatty liver, in which fat is deposited in the... -
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- The Current State and Future of Plasma Cell-Free DNA Analysis in Urologic Malignancies
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- KMID: 2542202
- J Urol Oncol.
- 2023 Mar;21(1):23-31.
- doi: 10.22465/juo.234600060003
Genomic medicine based on comprehensive genomic profiling (CGP) has revolutionized cancer treatment. However, there are certain limitations to CGP based on tissue analysis. Liquid biopsy, particularly plasma cell-free DNA (cfDNA),... -
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- Clinical Characteristics, Management, and Potential Biomarkers of Endocrine Dysfunction Induced by Immune Checkpoint Inhibitors
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Iwama S, Kobayashi T, Arima H
- KMID: 2515457
- Endocrinol Metab.
- 2021 Apr;36(2):312-321.
- doi: 10.3803/EnM.2021.1007
Immune-related adverse events (irAEs) affecting the endocrine glands are among the most frequent irAEs induced by immune checkpoint inhibitors (ICIs) and include hypopituitarism, primary adrenal insufficiency, thyrotoxicosis, hypothyroidism, hypoparathyroidism, and... -
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- Endoscopic Self-Expandable Metal Stent Placement for Malignant Afferent Loop Obstruction After Pancreaticoduodenectomy: A Case Series and Review
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Sakai A, Shiomi H, Iemoto T, Nakano R, Ikegawa T, Kobayashi T, Masuda A, Kodama Y
- KMID: 2504955
- Clin Endosc.
- 2020 Jul;53(4):491-496.
- doi: 10.5946/ce.2019.145
In this study, we assessed a series of our cases in which endoscopic self-expandable metal stents (SEMSs) were used to treat malignant afferent loop obstruction (ALO) that arose after pancreaticoduodenectomy... -
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- Endoscopic Ultrasound-Guided Gastroenterostomy for Afferent Loop Syndrome
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Shiomi H, Sakai A, Nakano R, Ota S, Kobayashi T, Masuda A, Iijima H
- KMID: 2522700
- Clin Endosc.
- 2021 Nov;54(6):810-817.
- doi: 10.5946/ce.2021.234
Afferent loop syndrome (ALS) is a mechanical obstruction of the afferent limbs after gastrectomy with gastrojejunostomy reconstruction. Patients with cancer recurrence require immediate and less invasive treatment because of their... -
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- Performing colonoscopy before steroid induction is associated with shorter steroid use in patients with ulcerative colitis
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Kobayashi T, Udagawa E, Hirose L, Hibi T
- KMID: 2541893
- Intest Res.
- 2023 Apr;21(2):205-215.
- doi: 10.5217/ir.2021.00164
Background/Aims: Risks of long-term steroid use in patients with ulcerative colitis (UC) outweigh the benefits, thus dosing should be tapered once a response is achieved. Colonoscopy is a key technique... -
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- Early change in serum leucine-rich α-2-glycoprotein predicts clinical and endoscopic response in ulcerative colitis
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Karashima R, Sagami S, Yamana Y, Maeda M, Hojo A, Miyatani Y, Nakano M, Matsuda T, Hibi T, Kobayashi T
- KMID: 2560297
- Intest Res.
- 2024 Oct;22(4):473-483.
- doi: 10.5217/ir.2023.00135
Background/Aims: Leucine-rich α-2-glycoprotein (LRG) is a new serum biomarker reflecting the disease activity of ulcerative colitis (UC), but its change during the acute phase has not been enough investigated. Methods:... -
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- Comparative advantages of activities with lumbosacral preservation for adult spinal deformity surgery: a retrospective Japanese cohort study
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Ishikawa Y, Kobayashi T, Abe E, Shoji R, Miyakoshi N
- KMID: 2560444
- Asian Spine J.
- 2024 Oct;18(5):699-705.
- doi: 10.31616/asj.2024.0217
Study Design: Retrospective cohort study. Purpose: This study aimed to demonstrate the advantages of preservation of the lumbosacral segment (LSS) in adult spinal deformity (ASD) surgery. Overview of Literature: Sacroiliac foundation enables... -
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- Human Leukocyte Antigens and Biomarkers in Type 1 Diabetes Mellitus Induced by Immune-Checkpoint Inhibitors
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Inaba H, Kaido Y, Ito S, Hirobata T, Inoue G, Sugita T, Yamamoto Y, Jinnin M, Kimura H, Kobayashi T, Iwama S, Arima H, Matsuoka T
- KMID: 2527140
- Endocrinol Metab.
- 2022 Feb;37(1):84-95.
- doi: 10.3803/EnM.2021.1282
Background: Type 1 diabetes mellitus induced by immune-checkpoint inhibitors (ICI-T1DM) is a rare critical entity. However, the etiology of ICI-T1DM remains unclear. Methods: In order to elucidate risk factors for ICI-T1DM,... -
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- A novel fully covered metal stent for unresectable malignant distal biliary obstruction: results of a multicenter prospective study
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Sakai A, Masuda A, Eguchi T, Furumatsu K, Iemoto T, Yoshida S, Okabe Y, Yamanaka K, Miki I, Kakuyama S, Yagi Y, Shirasaka D, Kohashi S, Kobayashi T, Shiomi H, Kodama Y
- KMID: 2555899
- Clin Endosc.
- 2024 May;57(3):375-383.
- doi: 10.5946/ce.2023.035
Background/Aims: Endoscopic self-expandable metal stent (SEMS) placement is currently the standard technique for treating unresectable malignant distal biliary obstructions (MDBO). Therefore, covered SEMS with longer stent patency and fewer migrations... -
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- Efficacy and safety of mirikizumab as induction and maintenance therapy for Japanese patients with moderately to severely active ulcerative colitis: a subgroup analysis of the global phase 3 LUCENT-1 and LUCENT-2 studies
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Kobayashi T, Matsuoka K, Watanabe M, Hisamatsu T, Hirai F, Milata J, Li X, Morris N, Arora V, Ishizuka T, Matsuo K, Satoi Y, Milch C, Hibi T
- KMID: 2554661
- Intest Res.
- 2024 Apr;22(2):172-185.
- doi: 10.5217/ir.2023.00043
Background/Aims: Mirikizumab is a p19-directed anti-interleukin-23 antibody with potential efficacy against ulcerative colitis (UC). We evaluated the efficacy and safety of mirikizumab in a Japanese subpopulation with moderately to severely... -
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- Efficacy and safety of a new vedolizumab subcutaneous formulation in Japanese patients with moderately to severely active ulcerative colitis
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Kobayashi T, Ito H, Ashida T, Yokoyama T, Nagahori M, Inaba T, Shikamura M, Yamaguchi T, Hori T, Pinton P, Watanabe M, Hibi T
- KMID: 2521608
- Intest Res.
- 2021 Oct;19(4):448-460.
- doi: 10.5217/ir.2020.00026
Background/Aims: A subgroup analysis was conducted in Japanese patients with moderate to severe ulcerative colitis (UC) enrolled in the phase 3 VISIBLE 1 study, which evaluated the safety and efficacy... -
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- Efficacy and safety of filgotinib as induction and maintenance therapy for Japanese patients with moderately to severely active ulcerative colitis: a post-hoc analysis of the phase 2b/3 SELECTION trial
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Hibi T, Motoya S, Hisamatsu T, Hirai F, Watanabe K, Matsuoka K, Saruta M, Kobayashi T, Feagan BG, Tasset C, Besuyen R, Yun C, Crans G, Zhang J, Kondo A, Watanabe M
- KMID: 2539010
- Intest Res.
- 2023 Jan;21(1):110-125.
- doi: 10.5217/ir.2021.00143
Background/Aims: The safety and efficacy of filgotinib, a once-daily oral Janus kinase 1 preferential inhibitor, were evaluated in Japanese patients with ulcerative colitis (UC) in the phase 2b/3 SELECTION trial. Methods:... -
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- Natural History of Chronic Intestinal Pseudo-obstruction and Need for Palliative Care
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Tanaka K, Ohkubo H, Yamamoto A, Takahashi K, Kasai Y, Ozaki A, Iwaki M, Kobayashi T, Yoshihara T, Misawa N, Fuyuki A, Kato S, Higurashi T, Hosono K, Yoneda M, Kurihashi T, Taguri M, Nakajima A, Gwee KA, Kessoku T
- KMID: 2544720
- J Neurogastroenterol Motil.
- 2023 Jul;29(3):378-387.
- doi: 10.5056/jnm22152
Background/Aims Natural history of chronic intestinal pseudo-obstruction (CIPO), a rare disease characterized by episodes of non-mechanical obstruction, is unclear in adults. This study evaluates the clinical course of CIPO and palliative... -
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