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State-of-the-Art Strategies for the Vascularization of Three-Dimensional Engineered Organs

Min S, Ko IK, Yoo JJ

Engineering three-dimensional (3D) implantable tissue constructs is a promising strategy for replacing damaged or diseased tissues and organs with functional replacements. However, the efficient vascularization of new 3D organs is...
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Cell-derived Secretome for the Treatment of Renal Disease

Kim MW, Ko IK, Atala A, Yoo JJ

Kidney disease is a major global health issue. Hemodialysis and kidney transplantation have been used in the clinic to treat renal failure. However, the dialysis is not an effective long-term...
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In situ tissue regeneration through host stem cell recruitment

Ko IK, Lee SJ, Atala A, Yoo JJ

  • KMID: 2154276
  • Exp Mol Med.
  • 2013 Nov;45(11):e57.
The field of tissue engineering has made steady progress in translating various tissue applications. Although the classical tissue engineering strategy, which involves the use of culture-expanded cells and scaffolds to...
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Cell-based therapy for kidney disease

Chung HC, Ko IK, Atala A, Yoo JJ

The prevalence of renal disease continues to increase worldwide. When normal kidney is injured, the damaged renal tissue undergoes pathological and physiological events that lead to acute and chronic kidney...
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Bioactive Compounds for the Treatment of Renal Disease

Cho KS, Ko IK, Yoo JJ

Kidney diseases including acute kidney injury and chronic kidney disease are among the largest health issues worldwide. Dialysis and kidney transplantation can replace a significant portion of renal function, however...
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Mediastinal Lymph Node Metastasis from Head and Neck Cancer: Predictive Factors and Imaging Features

Ko IK, Yoon DY, Baek S, Hong JH, Yun EJ, Lee IJ

Purpose To assess the predictive factors and describe the imaging features of mediastinal lymph node (MLN) metastases in patients with head and neck cancer. Materials and Methods We compared the clinical...
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