- Expression of progesterone receptor in human keratinocytes
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Im S, Lee ES, Kim W, Song J, Kim J, Lee M, Kang WH
- KMID: 2157545
- J Korean Med Sci.
- 2000 Dec;15(6):647-654.
- doi: 10.3346/jkms.2000.15.6.647
Despite the various responses of human skin to female sex hormones, cellular and subcellular targets and the mechanisms of action of estrogen and progesterone in human skin are not well... -
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- Cell Therapy for Wound Healing
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You HJ, Han SK
- KMID: 1734915
- J Korean Med Sci.
- 2014 Mar;29(3):311-319.
- doi: 10.3346/jkms.2014.29.3.311
In covering wounds, efforts should include utilization of the safest and least invasive methods with goals of achieving optimal functional and cosmetic outcome. The recent development of advanced wound healing... -
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- Expression Profiling of Calcium Induced Genes in Cultured Human Keratinocytes
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Lee JS, Kim MR, Kim NS, Kim YS, Yang JM, Cho AY, Lee Y, Kim CD, Lee JH
- KMID: 1792935
- J Korean Med Sci.
- 2010 Apr;25(4):619-625.
- doi: 10.3346/jkms.2010.25.4.619
Terminal differentiation of skin keratinocytes is a vertically directed multi-step process that is tightly controlled by the sequential expression of a variety of genes. To examine the gene expression profile... -
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- Expression and Modulation of LL-37 in Normal Human Keratinocytes, HaCaT cells, and Inflammatory Skin Diseases
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Kim JE, Kim BJ, Jeong MS, Seo SJ, Kim MN, Hong CK, Ro BI
- KMID: 1712748
- J Korean Med Sci.
- 2005 Aug;20(4):649-654.
- doi: 10.3346/jkms.2005.20.4.649
Defensins and cathelicidins (LL-37) are major antimicrobial peptides (AMPs) of the innate immune system of the human skin. In normal non-inflamed skin these peptides are negligible, but their expression can... -
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- PKC alpha induces differentiation through ERK1/2 phosphorylation in mouse keratinocytes
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Seo HR, Kwan YW, Cho CK, Bae S, Lee SJ, Soh JW, Chung HY, Lee YS
- KMID: 1094073
- Exp Mol Med.
- 2004 Aug;36(4):292-299.
Epidermal keratinocyte differentiation is a tightly regulated stepwise process that requires protein kinase C (PKC) activation. Studies on cultured mouse keraitnocytes induced to differentiate with Ca2+ have indirectly implicated the... -
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- Recombinant tetra-cell adhesion motifs supports adhesion, migration and proliferation of keratinocytes/fibroblasts, and promotes wound healing
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Jung MY, Thapa N, Kim JE, Yang JD, Cho BC, Kim IS
- KMID: 1090969
- Exp Mol Med.
- 2007 Oct;39(5):663-672.
An extracellular matrix protein plays an important role in skin wound healing. In the present study, we engineered a recombinant protein encompassing the 9th and 10th type III domains of... -
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- Expression of Toll-Like Receptors in Verruca and Molluscum Contagiosum
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Ku JK, Kwon HJ, Kim MY, Kang H, Song PI, Armstrong , Ansel JC, Kim HO, Park YM
- KMID: 1713466
- J Korean Med Sci.
- 2008 Apr;23(2):307-314.
- doi: 10.3346/jkms.2008.23.2.307
Recent studies indicate that several Toll-like receptors (TLRs) are implicated in recognizing viral structures and instigating immune responses against viral infections. The aim of this study is to examine the... -
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- Current state-of-the-art in human cell transformation in culture
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Rhim JS
- KMID: 1729586
- Yonsei Med J.
- 1991 Sep;32(3):195-206.
- doi: 10.3349/ymj.1991.32.3.195
The immortalization and transformation of cultured human cells has far-reaching implications for both cell and cancer biology. Human cell transformation studies will increase our understanding of the mechanisms underlying carcinogenesis... -
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- Prediction of Microbial Infection of Cultured Cells Using DNA Microarray Gene-Expression Profiles of Host Responses
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Park YR, Chung TS, Lee YJ, Song YW, Lee EY, Sohn YW, Song S, Park WY, Kim JH
- KMID: 1778816
- J Korean Med Sci.
- 2012 Oct;27(10):1129-1136.
- doi: 10.3346/jkms.2012.27.10.1129
Infection by microorganisms may cause fatally erroneous interpretations in the biologic researches based on cell culture. The contamination by microorganism in the cell culture is quite frequent (5% to 35%).... -
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- Curcumin inhibits the expression of COX-2 in UVB-irradiated human keratinocytes (HaCaT) by inhibiting activation of AP-1: p38 MAP kinase and JNK as potential upstream targets
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Cho JW, Park K, Kweon GR, Jang BC, Baek WK, Suh MH, Kim CW, Lee KS, Suh SI
- KMID: 1056230
- Exp Mol Med.
- 2005 Jun;37(3):186-192.
Ultraviolet B (UVB) irradiation of skin induces an acute inflammation. Cyclooxygenase-2 (COX-2) protein plays key roles in acute inflammation in UVB-irradiated keratinocyte cell line HaCaT. Recently, curcumin has been regarded... -
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- Microarray Analysis for Genes Associated with Angiogenesis in Diabetic OLETF Keratocytes
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Park JM, Park YM, Jung W, Lee JE, Lee JS
- KMID: 1789986
- J Korean Med Sci.
- 2014 Feb;29(2):265-271.
- doi: 10.3346/jkms.2014.29.2.265
The purpose of this study was to identify the differences in angiogenesis gene expression between normal and diabetic keratocytes stimulated with interleukin-1alpha (IL-1alpha) and tumor necrosis factor-alpha (TNF-alpha). Primarily cultured... -
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