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Repeatability and Validity of the VAA-2000 Automated Self Vision Tester

Kee HJ, Yang HK

PURPOSE: To evaluate the test-retest reliability and validity of the VAA-2000 Self Vision Tester. METHODS: A total of 108 eyes of 108 adults (55 men and 53 women) who visited Seoul...
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A Case of Trochlear Nerve Schwannoma Presenting with Binocular Diplopia

Kee HJ, Yoo YJ, Kim JH, Yang HK

PURPOSE: To report a case of unilateral trochlear nerve schwannoma in a patient without neurofibromatosis. CASE SUMMARY: A 58-year-old male presented with acute onset of diplopia which developed 10 days prior....
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Clinical Characteristics of Autosomal Dominant Giant Platelet Syndromes and Mutation Analysis of MYH9

Kook H, Nam HS, Baek HJ, Kim YO, Eom GH, Kee HJ, Cho D, Shin MG, Lee JJ, Kim HJ, Kook H, Hwang TJ

BACKGROUND: The autosomal dominant giant platelet syndromes (GPS), characterized by triads of giant platelets, thrombocytopenia, and Dohle-like leukocyte inclusions are caused by MYH9 mutation, a gene encoding the nonmuscle myosin...
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Expression of Class I and Class II a/b Histone Deacetylase is Dysregulated in Hypertensive Animal Models

Kee HJ, Kim GR, Lin MQ, Choi SY, Ryu Y, Jin L, Piao ZH, Jeong MH

BACKGROUND AND OBJECTIVES: Dysregulation of histone deacetylase expression and enzymatic activity is associated with a number of diseases. It has been reported that protein levels of histone deacetylase (HDAC)1 and...
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Identification of Tumor Suppressor Loci on the Long Arm of Chromosome 15 in Primary Small Cell Lung Cancer

Kee HJ, Shin JH, Chang J, Chung KY, Shin DH, Kim YS, Kim SK, Kim SK

Small cell lung cancer (SCLC) frequently shows a loss of heterozygosity (LOH) on chromosome 15q. In order to define the commonly affected region on chromosome 15q, we tested 23 primary...
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Identification of Tumor Suppressor Loci on the Short Arm of Chromosome 16 in Primary Small Cell Lung Cancers

Kee HJ, Shin JH, Chang J, Chung KY, Shin DH, Kim YS, Chang YS, Kim SK, Kwak SM, Kim SK

  • KMID: 2318455
  • Tuberc Respir Dis.
  • 2003 Dec;55(6):597-611.
BACKGROUND: Loss of the short arm of chromosome 16 is a frequent event in various cancers, which suggests the presence of tumor suppressor gene(s) there. To map precise tumor suppressor...
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miR-18a-5p MicroRNA Increases Vascular Smooth Muscle Cell Differentiation by Downregulating Syndecan4

Kee HJ, Kim GR, Cho SN, Kwon JS, Ahn Y, Kook H, Jeong MH

BACKGROUND AND OBJECTIVES: Differentiation and de-differentiation of vascular smooth muscle cells (VSMCs) are important events in atherosclerosis and restenosis after angioplasty. MicroRNAs are considered a key regulator in cellular processes...
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Effect of Renal Denervation on Suppression of PVC and QT Prolongation in a Porcine Model of Acute Myocardial Infarction

Kim SS, Kim HK, Park HW, Jeong MH, Lim KS, Kee HJ, Ryu YH, Kim HB, Na JY, Ki YJ, Park KH, Choi DH, Lee KH, Yoon NS, Cho JG

BACKGROUND AND OBJECTIVES: Antiarrhythmic effect of renal denervation (RDN) after acute myocardial infarction (AMI) remains unclear. The goal of this study was to evaluate the effect of RDN on ventricular...
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Selective inhibition of histone deacetylase 8 improves vascular hypertrophy, relaxation, and inflammation in angiotensin II hypertensive mice

Kee HJ, Ryu Y, Seok YM, Choi SY, Sun S, Kim GR, Jeong MH

BACKGROUND: The dysregulation of histone deacetylase (HDAC) protein expression or its enzyme activity is implicated in a variety of diseases. Cardiac HDAC6 and HDAC8 enzyme activity induced by deoxycorticosterone acetate...
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