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Effect of Rutin on Diabetic Auditory Neuropathy in an Experimental Rat Model

Doostkam A, Mirkhani H, Iravani K, Karbalay-Doust S, Zarei K

Objectives. Diabetic auditory neuropathy is a common complication of diabetes mellitus that has a major impact on patients’ quality of life. In this study, we assessed the efficacy of rutin...
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Stress Changes the Spatial Arrangement of Neurons and Glial Cells of Medial Prefrontal Cortex and Sertraline and Curcumin Prevent It

Noorafshan A, Abdollahifar MA, Karbalay-Doust S

OBJECTIVE: The present study explored the three-dimensional spatial arrangements of the neurons and glial cells within the medial prefrontal cortex (mPFC) of rats. METHODS: It evaluated the arrangement for differences after...
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Sleep deprivation induces structural changes in the adult rat testis: The protective effects of olive oil

Karimi F, Noorafshan A, Karbalay-Doust S, Naseh M

Objective: Sleep deprivation (SD) is a common problem in today’s stressful lifestyle and have physiological consequences, including reproductive dysfunction and infertility. As an antioxidant, olive oil may be effective in...
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Taxol and Taurine Protect the Renal Tissue of Rats after Unilateral Ureteral Obstruction: A Stereological Survey

Karbalay-Doust S, Noorafshan A, Pourshahid SM

  • KMID: 2315587
  • Korean J Urol.
  • 2012 May;53(5):360-367.
PURPOSE: Blockage of the urinary tract induces changes in renal structure including tubular dilatation or atrophy, tubular cell death, inflammatory processes, and progressive interstitial fibrosis with the loss of renal...
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Stereological study of the diabetic heart of male rats

Noorafshan A, Khazraei H, Mirkhani H, Karbalay-Doust S

  • KMID: 2312098
  • Lab Anim Res.
  • 2013 Mar;29(1):12-18.
The present study aimed to quantitatively compare the normal and diabetic hearts of rats using stereological methods. Diabetic and control rats received streptozotocin (60 mg/kg) and no treatments, respectively. On...
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Diosmin Reduces Calcium Oxalate Deposition and Tissue Degeneration in Nephrolithiasis in Rats: A Stereological Study

Noorafshan A, Karbalay-Doust S, Karimi F

  • KMID: 2316040
  • Korean J Urol.
  • 2013 Apr;54(4):252-257.
PURPOSE: Kidney stones (nephrolithiasis) are a widespread disease. Thus, blocking stone formation and finding new therapeutic methods is an important area of study. Diosmin (a major component of the bile)...
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Curcumin, the Main Part of Turmeric, Prevents Learning and Memory Changes Induced by Sodium Metabisulfite, a Preservative Agent, in Rats

Noorafshan A, Asadi-Golshan R, Karbalay-Doust S, Abdollahifar MA, Rashidiani-Rashidabadi A

Sodium metabisulfite is used as a disinfectant, antioxidant, and preservative agent in the food, beverage, and drug industries. Neurons are highly sensitive to sulfite toxicity. Curcumin is the main part...
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Stereological study of the effects of letrozole and estradiol valerate treatment on the ovary of rats

Noorafshan A, Ahmadi M, Mesbah SF, Karbalay-Doust S

OBJECTIVE: Letrozole and estradiol valerate are used to treat some hormonally-responsive symptoms and also in modeling of the polycystic ovary syndrome. However, the stereological analysis of the ovary has received...
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Protective Effects of Curcumin and Sertraline on the Behavioral Changes in Chronic Variable Stress-Induced Rats

Noorafshan A, Abdollahifar MA, Karbalay-Doust S, Asadi-Golshan R, Rashidian-Rashidabadi A

Behavioral characteristics of the animal models and humans are impaired in chronic stress. The present study aimed to evaluate and compare the protective effects of sertraline and curcumin on stress-induced...
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Curcumin Can Prevent the Changes in Cerebellar Structure and Function Induced by Sodium Metabisulfite in Rat

Noorafshan A, Rashidiani-Rashidabadi A, Karbalay-Doust S, Poostpasand A, Abdollahifar MA, Asadi-Golshan R

Sulfites are used as anti-microbial and anti-oxidant agents in the food and pharmaceutical industries. Curcumin, a flavonoid, is an Asian spice that shows neuroprotective activities. The current study aimed to...
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