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Prediction of Prognosis in Glioblastoma Using Radiomics Features of Dynamic Contrast-Enhanced MRI

Pak E, Choi KS, Choi SH, Park CK, Kim TM, Park SH, Lee JH, Lee ST, Hwang I, Yoo RE, Kang KM, Yun TJ, Kim JH, Sohn CH

Objective: To develop a radiomics risk score based on dynamic contrast-enhanced (DCE) MRI for prognosis prediction in patients with glioblastoma. Materials and Methods: One hundred and fifty patients (92 male [61.3%];...
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Renal Safety of Repeated Intravascular Administrations of Iodinated or Gadolinium-Based Contrast Media within a Short Interval

Kwon C, Kang KM, Choi YH, Yoo RE, Sohn CH, Han SS, Yoon SH

Objective: We aimed to investigate whether repeated intravascular administration of iodinated contrast media (ICM) or gadolinium-based contrast agents (GBCAs) within a short interval was associated with an increased risk of...
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Prognostic Prediction Based on Dynamic Contrast-Enhanced MRI and Dynamic Susceptibility Contrast-Enhanced MRI Parameters from Non-Enhancing, T2-High-Signal-Intensity Lesions in Patients with Glioblastoma

Jo SW, Choi SH, Lee EJ, Yoo RE, Kang KM, Yun TJ, Kim JH, Sohn CH

Objective: Few attempts have been made to investigate the prognostic value of dynamic contrast-enhanced (DCE) MRI or dynamic susceptibility contrast (DSC) MRI of non-enhancing, T2-high-signal-intensity (T2-HSI) lesions of glioblastoma multiforme...
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Application of T1 Map Information Based on Synthetic MRI for Dynamic Contrast-Enhanced Imaging: A Comparison Study with the Fixed Baseline T1 Value Method

Shin DJ, Choi SH, Yoo RE, Kang KM, Yun TJ, Kim JH, Sohn CH, Jo SW, Lee EJ

Objective: For an accurate dynamic contrast-enhanced (DCE) MRI analysis, exact baseline T1 mapping is critical. The purpose of this study was to compare the pharmacokinetic parameters of DCE MRI using...
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Cerebrovascular Reservoir and Arterial Transit Time Changes Assessed by Acetazolamide-Challenged Multi-Phase Arterial Spin Labeling Perfusion MRI in Chronic Cerebrovascular Steno-Occlusive Disease

Hwang I, Sohn CH, Jung KH, Yeon EK, Lee JY, Yoo RE, Kang KM, Yun TJ, Choi SH, Kim Jh

Purpose: To explore cerebrovascular reservoir (CVR) and arterial transit time (ATT) changes using acetazolamide-challenged multi-phase arterial spin labeling (MP-ASL) perfusion-weighted MRI in chronic cerebrovascular steno-occlusive disease. Materials and Methods: This retrospective...
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Comparison of Genetic Profiles and Prognosis of High-Grade Gliomas Using Quantitative and Qualitative MRI Features: A Focus on G3 Gliomas

Hong EK, Choi SH, Shin DJ, Jo SW, Yoo RE, Kang KM, Yun TJ, Kim Jh, Sohn CH, Park SH, Won JK, Kim TM, Park CK, Kim IH, Lee ST

Objective: To evaluate the association of MRI features with the major genomic profiles and prognosis of World Health Organization grade III (G3) gliomas compared with those of glioblastomas (GBMs). Materials and...
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Blood-Brain Barrier Disruption in Mild Traumatic Brain Injury Patients with Post-Concussion Syndrome: Evaluation with Region-Based Quantification of Dynamic Contrast-Enhanced MR Imaging Parameters Using Automatic Whole-Brain Segmentation

Yoen H, Yoo RE, Choi SH, Kim E, Oh BM, Yang D, Hwang I, Kang KM, Yun TJ, Kim Jh, Sohn CH

Objective: This study aimed to investigate the blood-brain barrier (BBB) disruption in mild traumatic brain injury (mTBI) patients with post-concussion syndrome (PCS) using dynamic contrast-enhanced (DCE) magnetic resonance (MR) imaging...
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Treatment Patterns and Clinical Outcomes in Elderly Patients with Breast Cancer

Kang KM, Kim EK, Kim H, Kim JH, Kim SH, Suh KJ, Kim IA, Chae S, Kim SW, Kang E

Purpose: Although the number of elderly patients with breast cancer is increasing as the population ages, their treatment is controversial. We evaluated the prognostic factors associated with survival in elderly...
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Prognostic Value of Dynamic Contrast-Enhanced MRI-Derived Pharmacokinetic Variables in Glioblastoma Patients: Analysis of Contrast-Enhancing Lesions and Non-Enhancing T2 High-Signal Intensity Lesions

Kang Y, Hong EK, Rhim JH, Yoo RE, Kang KM, Yun TJ, Kim JH, Sohn CH, Park SW, Choi SH

Objective: To evaluate pharmacokinetic variables from contrast-enhancing lesions (CELs) and non-enhancing T2 high signal intensity lesions (NE-T2HSILs) on dynamic contrast-enhanced (DCE) magnetic resonance (MR) imaging for predicting progression-free survival (PFS)...
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Ultrasonographic Indeterminate Lymph Nodes inPreoperative Thyroid Cancer Patients: Malignancy Riskand Ultrasonographic Findings Predictive of Malignancy

Yoo RE, Kim Jh, Bae JM, Hwang I, Kang KM, Yun TJ, Choi SH, Sohn CH, Rhim JH, Park SW

Objective: Proper management of lymph nodes (LNs) with ultrasonographic (US) indeterminate features in thyroid cancer patients remains elusive. We aimed to evaluate the malignancy risk and US findings predictive of malignancy...
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Inhibitory effect of pomegranate extract powder on periodontitis in rat

Kim JH, Lee KH, Sung SJ, Kang KM, Lim YK, Kook JK, Lee WP, Kim BO, Yu SJ

This study aimed to investigate the effect of pomegranate extract (PE) on the progression of periodontal disease in an experimental rat model of periodontitis. Periodontitis was induced in rats by...
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Effect of Garcinia mangostana L. and propolis extracts on the inhibition of inflammation and alveolar bone loss in ligature-induced periodontitis in rats

Sung SJ, Kang KM, Lee KH, Yoo SY, Kook JK, Lee DS, Yu SJ

The purpose of this study was to evaluate the effect of mangosteen extract complex (MEC; Garcinia mangostana L. and propolis extracts) on the inhibition of inflammation and prevention of alveolar...
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Application of Synthetic MRI for Direct Measurement of Magnetic Resonance Relaxation Time and Tumor Volume at Multiple Time Points after Contrast Administration: Preliminary Results in Patients with Brain Metastasis

Kang KM, Choi SH, Hwang M, Yoo RE, Yun TJ, Kim JH, Sohn CH

OBJECTIVE: The purpose of this study was to investigate the time-dependent effects of contrast medium on multi-dynamic, multi-echo (MDME) sequence in patients with brain metastases. MATERIALS AND METHODS: This study included...
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Who Really Benefits from 3D-Based Planning of Brachytherapy for Cervical Cancer?

Ha IB, Jeong BK, Kang KM, Jeong H, Lee YH, Choi HS, Lee JH, Choi WJ, Shin JK, Song JH

BACKGROUND: Although intracavitary radiotherapy (ICR) is essential for the radiation therapy of cervical cancer, few institutions in Korea perform 3-dimensional (3D)-based ICR. To identify patients who would benefit from 3D-based...
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Analysis of Motion-dependent Clinical Outcome of Tumor Tracking Stereotactic Body Radiotherapy for Prostate Cancer

Choi HS, Kang KM, Jeong BK, Song JH, Lee YH, Ha IB, Kam SC, Hwa JS, Hyun JS, Do J, Jeong DH, Jeong H

BACKGROUND: To analyze clinical outcome of CyberKnife (CK) tumor-tracking stereotactic body radiotherapy (SBRT) for prostate cancer (Pca) according to the magnitude of intra-fractional prostate motion. METHODS: Medical records and daily treatment...
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Review of regulatory management on standards and specifications for veterinary medical devices in Korea

Kang KM, Kim TW, Kwon OR, Park HJ, Cho SM, Kim CH, Lee MH, Moon JS

Well-established standards and specifications for medical devices not only provide clarity and consistency in licensing processes but also secure device safety and effectiveness. This study reviewed regulatory standards and specifications...
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A Case of Sarcomatoid Cholangiocarcinoma Which Developed at the Site Previously Treated by Transarterial Chemoembolization

Lee C, Kang KM, Lee HL, Lee SW, Lee H, Han NI

Intrahepatic sarcomatoid carcinoma is a rare tumor with poor prognosis due to its highly invasive and metastatic nature and difficulty for early detection. The most common form of intrahepatic sarcomatoid...
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Carrier screening for (CGG)n repeat expansion of FMR1 gene in Korean women

Kang KM, Sung SR, Park JE, Shin YJ, Park SH, Chin MU, Lyu SW, Cha DH, Shim SH

PURPOSE: We examined the prevalence and CGG/AGG repeat structure of expanded alleles of the FMR1 gene in preconceptional and pregnant Korean women. MATERIALS AND METHODS: The CGG repeats in the FMR1...
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Carotid sparing intensity modulated radiotherapy on early glottic cancer: preliminary study

Choi HS, Jeong BK, Jeong H, Song JH, Kim JP, Park JJ, Woo SH, Kang KM

PURPOSE: To compare the dose distribution between carotid sparing intensity modulated radiotherapy (IMRT) and opposed lateral field technique (LAFT), and to determine the effects of carotid sparing IMRT in early...
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A Study of Relationship of Atheroembolic Risk Factors with Postoperative Recovery in Renal Function after Partial Nephrectomy in Patients Staged T1-2 Renal Cell Carcinoma during Median 4-Year Follow-up

Kim SH, Kang KM, Yu A, Lee JH, Nam BH, Lee ES

PURPOSE: The objective of this study is to evaluate the relationship of atheroembolic risk factors with postoperative recovery of renal function after on-clamp partial nephrectomy (PN) with warm ischemia in...
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