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Morphological Features of the Most Advanced Intra-Tumor Component in Multistep Progression

Yatabe Y

Advances in basic life science during the past decade have exponentially increased our understanding of the molecular bases of lung cancers and this improved insight has had great effects on...
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Inhibitory Effect of Epidermal Growth Factor on the Proliferation of Lung Cancer Cell Lines

Lee SH, Wu HG

PURPOSE: Epidermal growth factor (EGF) is known to cause cellular proliferation, differentiation and survival. However, there are a few articles that have reported on the cell killing effect of EGF....
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Mutational and Expressional Analysis of ATG5 Gene in Non-Small Cell Lung Cancers

Kim MS, Yoo NJ, Lee SH

PURPOSE: Several lines of evidence have indicated that perturbations of autophagy are involved in the development of many human diseases, including cancer. The autophagy-related genes (ATG) encode proteins that play...
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Female Lung Cancer: Re-Analysis of National Survey of Lung Cancer in Korea, 2005

Jang TW, Kim YC, Kwon YS, Oh IJ, Kim KS, Kim SY, Ryu JS, Yum HK, Lee KH, Yong SJ, Lee CG, Lee SY, Lee SY, Jeong ET, In KH, Jung MH

PURPOSE: Female lung cancers have different clinical features and therapeutic results as compared to those of male lung cancers. The aim of this study was to analyze the differences of...
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Tumor Lysis Syndrome Induced by Radiotherapy in Non-Small Cell Lung Cancer

Noh DH, Hwang KE, Shin JH, Kim D, Cho KH, Choi KH, Park SH, Jeong ET, Kim HR

Tumor lysis syndrome (TLS) is an oncologic emergency that is characterized by numerous metabolic abnormalities, including hyperuricemic nephropathy, hyperphosphatemia, hypocalcemia, hyperkalemia and increased serum creatinine. This syndrome is common for...
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IgG4-Related Lung Disease Presenting as a Consolidative Mass: A Case Report

Park HY, Han J, Kang G, Yi CA, Chung MP

Immunoglobulin G4 (IgG4)-related sclerosing disease involving the lung is a rare condition, and this is characterized by an elevated serum IgG4 level, fibrotic inflammation with numerous IgG4-positive plasma cells and...
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Combination Therapy of Bortezomib (PS-341) and SAHA (Vorinostat) in Non-Small Cell Lung Cancer Cell Lines

Park MY, Kim DR, Park JS, Cho YJ, Lee SW, Yoon HI, Lee JH, Lee CT

PURPOSE: The recent introduction of targeted therapy for non-small cell lung cancer (NSCLC) has changed the paradigm of lung cancer chemotherapy. However, only a small portion of NSCLC patients received...
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Pulmonary Metastasectomy for Colorectal Carcinoma

Choi KH, Lee YH, Park KT, Han IY, Yoon YC, Cho KH

PURPOSE: Surgical resection is an important curative treatment for pulmonary metastases from colorectal adenocarcinoma. We analyzed the outcomes and the prognostic factors related to the post operative mortality after surgical...
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High-Dose Involved Field Radiotherapy and Concurrent Chemotherapy for Limited-Disease Small Cell Lung Cancer

Jang NY, Kim JS, Lee JS, Song CH

PURPOSE: We wanted to evaluate the effect of high dose involved field radiotherapy and concurrent chemotherapy for treating patients with limited disease, small cell lung cancer. MATERIALS AND METHODS: We reviewed...
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Serum Carcinoembryonic Antigen as an Index of the Therapeutic Effect of EGFR-TKIs in Patients with Advanced Non-Small Cell Lung Cancer

Park JH, Kim SB, Nam SJ, Jeong SH, Oak CH, Jang TW, Jung MH

PURPOSE: For treating advanced non-small cell lung cancer (NSCLC), epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) are known to be very effective in nonsmokers, women, Asian and person with...
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