- Single Cell RNA-Sequencing for the Study of Atherosclerosis
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Hajkarim M, Won KJ
- KMID: 2458380
- J Lipid Atheroscler.
- 2019 Sep;8(2):152-161.
- doi: 10.12997/jla.2019.8.2.152
Atherosclerosis is a major cause of coronary artery disease and stroke. A massive and new type of data has finally arrived in the field of atherosclerosis: single cell RNA sequencing... -
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- Should We Intensify Statin Management in ACS Patients with Very Low LDL Cholesterol Levels?
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Han KH
- KMID: 2458385
- J Lipid Atheroscler.
- 2019 Sep;8(2):204-207.
- doi: 10.12997/jla.2019.8.2.204
No abstract available. -
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- Nutritional Therapy for Asian Patients at Risk for Atherosclerotic Cardiovascular Disease
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Lim H, Kim J, Kim DY
- KMID: 2458384
- J Lipid Atheroscler.
- 2019 Sep;8(2):192-203.
- doi: 10.12997/jla.2019.8.2.192
The burden of atherosclerotic cardiovascular disease (ASCVD) remains high worldwide, and its prevalence has increased in Asian countries over the last two decades. The increase in ASCVD may arise from... -
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- Genetically Mediated Lipid Metabolism and Risk of Insulin Resistance: Insights from Mendelian Randomization Studies
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Bu SY
- KMID: 2458378
- J Lipid Atheroscler.
- 2019 Sep;8(2):132-143.
- doi: 10.12997/jla.2019.8.2.132
Dysregulated lipid metabolism, characterized by higher levels of circulating triglycerides, higher levels of small, low density lipoprotein, and accumulation of intracellular lipids, is linked to insulin resistance and related complications... -
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- Analysis of ¹â¸F-Fluorodeoxyglucose and ¹â¸F-Fluoride Positron Emission Tomography in Korean Stroke Patients with Carotid Atherosclerosis
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Kim JM, Lee ES, Park KY, Seok JW, Kwon OS
- KMID: 2458388
- J Lipid Atheroscler.
- 2019 Sep;8(2):232-241.
- doi: 10.12997/jla.2019.8.2.232
OBJECTIVE: The objective of this study was to analyze uptake patterns and intensity of ¹â¸F-fluorodeoxyglucose (FDG) and ¹â¸F-sodium fluoride (NaF) radioligands in carotid atheroma among stroke patients according to carotid... -
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- Diabetes-related Amylin Dyshomeostasis: a Contributing Factor to Cerebrovascular Pathology and Dementia
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Ly H, Despa F
- KMID: 2458379
- J Lipid Atheroscler.
- 2019 Sep;8(2):144-151.
- doi: 10.12997/jla.2019.8.2.144
Type 2 diabetes (T2D) increases the risk for cerebrovascular disease (CVD) and dementia. The underlying molecular mechanisms remain elusive, which hampers the development of treatment or/and effective prevention strategies. Recent... -
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- Anti-malarial Drugs Reduce Vascular Smooth Muscle Cell Proliferation via Activation of AMPK and Inhibition of Smad3 Signaling
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Lee H, Han JH, Kim S, Kim S, Cho DH, Woo CH
- KMID: 2458392
- J Lipid Atheroscler.
- 2019 Sep;8(2):267-276.
- doi: 10.12997/jla.2019.8.2.267
OBJECTIVE: The aim of this study was to investigate the effects of 2 anti-malarial drugs, chloroquine (CQ) and hydroxychloroquine (HCQ), on inhibition of vascular smooth muscle cell (VSMC) proliferation both... -
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- Aspirin for Primary Prevention of Cardiovascular Disease
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Kim JH, Shim MJ, Lee SY, Oh J, Kim SH
- KMID: 2458381
- J Lipid Atheroscler.
- 2019 Sep;8(2):162-172.
- doi: 10.12997/jla.2019.8.2.162
Aspirin has been used for decades for the primary and secondary prevention of cardiovascular disease (CVD). The effect of aspirin in secondary prevention is well-known but is still debatable for... -
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- Mendelian Randomization Analysis in Observational Epidemiology
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Lee K, Lim CY
- KMID: 2458376
- J Lipid Atheroscler.
- 2019 Sep;8(2):67-77.
- doi: 10.12997/jla.2019.8.2.67
Mendelian randomization (MR) in epidemiology is the use of genetic variants as instrumental variables (IVs) in non-experimental design to make causality of a modifiable exposure on an outcome or disease.... -
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- Pharmacological Strategies beyond Statins: Ezetimibe and PCSK9 Inhibitors
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Choi JY, Na JO
- KMID: 2458383
- J Lipid Atheroscler.
- 2019 Sep;8(2):183-191.
- doi: 10.12997/jla.2019.8.2.183
Dyslipidemia, highly elevated, low-density lipoprotein (LDL) cholesterol, is a major cardiovascular risk factor. Statins have been proven to effectively reduce the risk of atherosclerotic cardiovascular disease (ASCVD) and are recommended... -
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- The Potential Role of Biomarkers Associated with ASCVD Risk: Risk-Enhancing Biomarkers
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Choi S
- KMID: 2458382
- J Lipid Atheroscler.
- 2019 Sep;8(2):173-182.
- doi: 10.12997/jla.2019.8.2.173
Serum cholesterol is major risk factor and contributor to atherosclerotic cardiovascular disease (ASCVD). Therapeutic cholesterol-lowering drugs, especially statin, revealed that reduction in low-density lipoprotein cholesterol (LDL-C) produces marked reduction of... -
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- Dyslipidemia and Rate of Under-Target Low-Density Lipoprotein-Cholesterol in Patients with Coronary Artery Disease in Korea
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Lee SH, Song WH, Jeong MH, Hur SH, Jeon DW, Jeung W, Gitt AK, Horack M, Vyas A, Lautsch D, Ambegaonkar B, Brudi P, Jang Y
- KMID: 2458389
- J Lipid Atheroscler.
- 2019 Sep;8(2):242-251.
- doi: 10.12997/jla.2019.8.2.242
OBJECTIVE: The aim of this study was to evaluate under target rates of low-density lipoprotein-cholesterol (LDL-C) in Korean patients with stable coronary artery disease (CAD) or an acute coronary syndrome... -
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- 2018 Guidelines for the Management of Dyslipidemia in Korea
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Rhee EJ, Kim HC, Kim JH, Lee EY, Kim BJ, Kim EM, Song Y, Lim JH, Kim HJ, Choi S, Moon MK, Na JO, Park KY, Oh MS, Han SY, Noh J, Yi KH, Lee SH, Hong SC, Jeong IK, On behalf of the Committee of Clinical Practice Guideline of Korean Society of Lipid and Atherosclerosis
- KMID: 2458377
- J Lipid Atheroscler.
- 2019 Sep;8(2):78-131.
- doi: 10.12997/jla.2019.8.2.78
No abstract available. -
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- Effects of Obesity and Family History of Diabetes on the Association of CETP rs6499861 with HDL-C Level in Korean Populations
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Sull JW, Kim S, Jee SH
- KMID: 2458390
- J Lipid Atheroscler.
- 2019 Sep;8(2):252-257.
- doi: 10.12997/jla.2019.8.2.252
OBJECTIVES: The aim of this study was to examine the associations of cholesterol ester transfer protein (CETP) rs6499861 and rs12708980 with high-density lipoprotein cholesterol (HDL-C) considering obesity and family history... -
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- Efficacy and Safety of Prescription Omega-3 Fatty Acids Added to Stable Statin Therapy in Korean Patients with Type 2 Diabetes and Hypertriglyceridemia: a Randomized Controlled Trial
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Son JW, Kim CH, Nam MS, Park IB, Yoo SJ
- KMID: 2458387
- J Lipid Atheroscler.
- 2019 Sep;8(2):221-231.
- doi: 10.12997/jla.2019.8.2.221
OBJECTIVE: The aim of this study was to investigate the effects of omega-3 fatty acids added to statin monotherapy in Korean patients with type 2 diabetes who have persistent hypertriglyceridemia... -
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- Differing Associations between Fatty Liver and Dyslipidemia According to the Degree of Hepatic Steatosis in Korea
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Han JM, Kim HI, Lee YJ, Lee JW, Kim KM, Bae JC
- KMID: 2458391
- J Lipid Atheroscler.
- 2019 Sep;8(2):258-266.
- doi: 10.12997/jla.2019.8.2.258
OBJECTIVE: Fatty liver is associated with insulin resistance-related diseases, such as dyslipidemia, obesity, and type 2 diabetes. The aim of this study was to evaluate the association of dyslipidemia with... -
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- Intensity of Statin Treatment in Korean Patients with Acute Myocardial Infarction and Very Low LDL Cholesterol
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Sim DS, Jeong MH, Kim HS, Gwon HC, Seung KB, Rha SW, Chae SC, Kim CJ, Cha KS, Park JS, Yoon JH, Chae JK, Joo SJ, Choi DJ, Hur SH, Seong IW, Cho MC, Kim DI, Oh SK, Ahn TH, Hwang JY, on behalf of the Korea Acute Myocardial Infarction Registry-National Institutes of Health (KAMIR-NIH) registry investigators
- KMID: 2458386
- J Lipid Atheroscler.
- 2019 Sep;8(2):208-220.
- doi: 10.12997/jla.2019.8.2.208
OBJECTIVE: Data on the intensity of statin therapy for patients with acute myocardial infarction (MI) and very low baseline low-density lipoprotein (LDL) cholesterol level are lacking. We sought to assess... -
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