J Lipid Atheroscler.  2019 Sep;8(2):204-207. 10.12997/jla.2019.8.2.204.

Should We Intensify Statin Management in ACS Patients with Very Low LDL Cholesterol Levels?

• Han KH

• KMID: 2458385
• DOI: http://doi.org/10.12997/jla.2019.8.2.204

Abstract

No abstract available.

MeSH Terms

Cholesterol, LDL*
Humans
Hydroxymethylglutaryl-CoA Reductase Inhibitors*
Cholesterol, LDL

Reference

1. Catapano AL, Graham I, De Backer G, Wiklund O, Chapman MJ, Drexel H, et al. 2016 ESC/EAS guidelines for the management of dyslipidaemias. Eur Heart J. 2016; 37:2999–3058.

2. Wilson PW, Polonsky TS, Miedema MD, Khera A, Kosinski AS, Kuvin JT. Systematic review for the 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA guideline on the management of blood cholesterol: a report of the American College of Cardiology/American Heart Association task force on clinical practice guidelines. Circulation. 2019; 139:e1144–e1161.

3. Cannon CP, Blazing MA, Giugliano RP, McCagg A, White JA, Theroux P, et al. Ezetimibe added to statin therapy after acute coronary syndromes. N Engl J Med. 2015; 372:2387–2397.

4. Sim DS, Jeong MH, Kim HS, Gwon HC, Seung KB, Rha SW, et al. Intensity of statin treatment in Korean patients with acute myocardial infarction and very low LDL cholesterol. J Lipid Atheroscler. 2019; 8:208–220.

5. Sabatine MS, Giugliano RP, Keech AC, Honarpour N, Wiviott SD, Murphy SA, et al. Evolocumab and clinical outcomes in patients with cardiovascular disease. N Engl J Med. 2017; 376:1713–1722.

6. Schwartz GG, Steg PG, Szarek M, Bhatt DL, Bittner VA, Diaz R, et al. Alirocumab and cardiovascular outcomes after acute coronary syndrome. N Engl J Med. 2018; 379:2097–2107.

7. Rallidis LS, Kiouri E, Katsimardos A, Kotakos C. Extreme-risk category: high prevalence among stable coronary patients and an emerging widening treatment gap in achieving LDL-cholesterol less than 55 mg/dL. Atherosclerosis. 2018; 275:262–264.

8. Grundy SM, Stone NJ, Bailey AL, Beam C, Birtcher KK, Blumenthal RS, et al. 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA guideline on the management of blood cholesterol: executive summary: a report of the American College of Cardiology/American Heart Association task force on clinical practice guidelines. Circulation. 2019; 139:e1046–e1081.

9. Grundy SM, Stone NJ, Bailey AL, Beam C, Birtcher KK, Blumenthal RS, et al. 2018 AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA guideline on the management of blood cholesterol: a report of the American College of Cardiology/American Heart Association task force on clinical practice guidelines. Circulation. 2019; 139:e1082–e1143.

10. Cho KH, Jeong MH, Ahn Y, Kim YJ, Chae SC, Hong TJ, et al. Low-density lipoprotein cholesterol level in patients with acute myocardial infarction having percutaneous coronary intervention (the cholesterol paradox). Am J Cardiol. 2010; 106:1061–1068.

11. McKinney JS, Kostis WJ. Statin therapy and the risk of intracerebral hemorrhage: a meta-analysis of 31 randomized controlled trials. Stroke. 2012; 43:2149–2156.

12. Chun KH, Im E, Kim BK, Shin DH, Kim JS, Ko YG, et al. Incidence, predictors, and clinical outcomes of new-onset diabetes mellitus after percutaneous coronary intervention with drug-eluting stent. J Korean Med Sci. 2017; 32:1603–1609.