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Deflazacort for Type-1 Autoimmune Hepatitis in a Korean Girl

Bae SH, Kim JS, Kim DH

Prednisone or prednisolone are the mainstay drug treatments for autoimmune hepatitis in children. However, long-term use of corticosteroid is associated with the risk of steroid-induced toxicities, and this situation requires...
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Giant Fibrovascular Polyp of the Hypopharynx: Surgical Treatment with the Biappoach

I H, Kim JS, Shim YM

Fibrovascular polyps of the esophagus and hypopharynx are benign tumors of the upper digestive tract. The majority of these polyps are located in the upper part of the esophagus but...
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Clinical Experiences of Fetal Ovarian Cyst: Diagnosis and Consequence

Kwak DW, Sohn YS, Kim SK, Kim IK, Park YW, Kim YH

Ovarian cysts are the most frequent, prenatally diagnosed intra-abdominal cysts. Fetal ovarian cyst often presents complication such as torsion and seems to be an indication for surgical intervention. In this...
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Vigabatrin and Visual Field Defects in Pediatric Epilepsy Patients

You SJ, Ahn HS, Ko TS

We studied the prevalence, type and severity of vigabatrin (VGB)-attributed visual field defects (VFDs), and used these data to assess the associated risk factors in pediatric patients. Medical records were...
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Clinical and Genetic Analysis of Korean Patients with Miyoshi Myopathy: Identification of Three Novel Mutations in the DYSF Gene

Cho HJ, Sung DH, Kim EJ, Yoon CH, Ki CS, Kim JW

Miyoshi myopathy (MM) is an autosomal recessive distal muscular dystrophy caused by mutations in the dysferlin gene (DYSF) on chromosome 2p13. Although MM patients and their mutations in the DYSF...
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Recurrent Juvenile Nasopharyngeal Angiofibroma Treated with Gamma Knife Surgery

Park CK, Kim DG, Paek SH, Chung HT, Jung HW

Radiosurgery has been rarely applied for juvenile nasopharyngeal angiofibroma (JNA) and cumulative reports are lacking. The authors report a case of successful treatment of recurred JNA with gamma knife surgery...
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Intradural Disc Herniation at L5-S1 Mimicking an Intradural Extramedullary Spinal Tumor: A Case Report

Lee JS, Suh KT

Intradural lumbar disc herniation is a rare pathological entity. The pathogenesis of intradural lumbar disc herniation is not known clearly. Intradural disc herniations usually occurred at the L4-L5 levels but...
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Peutz-Jeghers Syndrome with Multiple Genital Tract Tumors and Breast Cancer: A Case Report with a Review of Literatures

Song SH, Lee JK, Saw HS, Choi SY, Koo BH, Kim A, Yeom BW, Kim I

We report here on the multiple genital tract neoplasms in a 41-yr-old Korean woman with Peutz-Jeghers Syndrome (PJS). The patient presented with lower abdominal pain. Her previous medical history was...
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Primary Osteosarcoma in Patients Older than 40 Years of Age

Jeon DG, Lee SY, Cho WH, Song WS, Park JH

Among the 665 patients who registered at our hospital, we reviewed 39 cases of high grade primary osteosarcoma in patients who were older than 40 yr of age. The aim...
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Metabolic Syndrome Is Associated with Delayed Heart Rate Recovery after Exercise

Sung J, Choi YH, Park JB

Heart rate (HR) recovery after exercise is a function of vagal reactivation, and its impairment is a predictor of overall mortality and adverse cardiovascular events. While metabolic syndrome is associated...
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A Case of Hyperglycemic Hyperosmolar State Associated with Graves' Hyperthyroidism: A Case Report

Moon SW, Hahm JR, Lee GW, Kang MY, Jung JH, Jung TS, Lee KW, Jung KA, Ahn YJ, Kim S, Kim MA, Kim DR, Chung SI, Park MH

Hyperglycemic hyperosmolar state (HHS) is an acute complication mostly occurring in elderly type 2 diabetes mellitus (DM). Thyrotoxicosis causes dramatic increase of glycogen degradation and/or gluconeogenesis and enhances breakdown of...
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Drug Hypersensitivity to Previously Tolerated Phenytoin by Carbamazepine-induced DRESS Syndrome

Kim CW, Choi GS, Yun CH, Kim DI

Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome associated with anticonvulsant drugs is a rare but potentially life-threatening disease that occurs in response to arene oxide producing anticonvulsant such...
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Endoscopic Dacryocystorhinostomy: Creation of a Large Marsupialized Lacrimal Sac

Jin HR, Yeon JY, Choi MY

This retrospective study describes and evaluates the effectiveness of a modified technique of conventional endoscopic dacryocystorhinostomy (DCR) that minimizes the obstruction of a neo-ostium by creating an enlarged marsupialized lacrimal...
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Comparison of Serum Beta 2-Microglobulin and 24 hour Urinary Creatinine Clearance as a Prognostic Factor in Multiple Myeloma

Yun JP, Suh C, Lee E, Chang JW, Yang WS, Park JS, Park SK

A new staging system for multiple myeloma (MM) has utilized serum concentrations of beta 2-microglobulin (S beta2 M) and albumin as important prognostic factors for survival. Since S beta2 M...
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Myxedema Ascites: Case Report and Literature Review

Ji JS, Chae HS, Cho YS, Kim HK, Kim SS, Kim CW, Lee CD, Lee BI, Choi H, Lee KM, Lee HK, Choi KY

Myxedema ascites caused by hypothyroidism is rare, so its diagnosis is often delayed and patients frequently receive unnecessary procedures such as liver biopsies and exploratory laparotomies. We report a 71-yr-old...
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Clinical and Radiological Manifestations of Osteogenesis Imperfecta Type V

Lee DY, Cho TJ, Choi IH, Chung CY, Yoo WJ, Kim JH, Park YK

We reviewed clinical manifestation of 12 patients from three Korean families. They showed mild to moderate bone fragility, and suggested an autosomal dominant inheritance pattern. Significant intrafamilial phenotype variability was...
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Granulocyte Antibodies in Korean Neonates with Neutropenia

Han TH, Chey MJ, Han KS

Neonatal alloimmune neutropenia (NAN) is a disease that can cause severe and prolonged neutropenia in neonates. However, no report is available on the incidence of granulocyte antibody in neonates, the...
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Nonleukemic Granulocytic Sarcoma in the Bile Duct: A Case Report

Kim HW, Choi SJ, Lee JH, Lee JH, Kim TS, Kim YG, Kang JM, Huh J, Park KM, Lee KH

Granulocytic sarcoma (GS) is an extramedullary tumor composed of immature myeloid cells, typically occurring during the course of acute myelogenous leukemia. Non-leukemic GS, that is, GS with no evidence of...
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Antigen-binding Characteristics of Circulating IgG Autoantibodies to Cytokeratin 18 Protein in Patients with Nonallergic Asthma

Yim H, Kim JE, Shin JY, Ye YM, Park HS, Nahm DH

Cytokeratin 18 (CK18) protein was identified as an airway epithelial cell autoantigen associated with nonallergic asthma. Cleavage of CK18 protein by caspase-3 is a marker of early apoptosis in epithelial...
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MET Expression in Sporadic Renal Cell Carcinomas

Choi JS, Kim MK, Seo JW, Choi YL, Kim DH, Chun YK, Ko YH

Although germline mutations of met proto-oncogene on human chromosome 7q31-34 have been known as useful molecular markers of hereditary papillary renal cell carcinoma (RCC), the expression of MET, a product...
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