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Does the adoption of sentinel node mapping allow to design a new trial testing the value of retroperitoneal staging in endometrial cancer?

Bogani G, Raspagliesi F

No abstract available.
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Immunotherapy in endometrial cancer: new scenarios on the horizon

Di Tucci C, Capone C, Galati G, Iacobelli , Schiavi MC, Di Donato , Muzii L, Panici PB

This extensive review summarizes clinical evidence on immunotherapy and targeted therapy currently available for endometrial cancer (EC) and reports the results of the clinical trials and ongoing studies. The research...
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Dietary inflammatory index and risk of gynecological cancers: a systematic review and meta-analysis of observational studies

Liu ZY, Gao XP, Zhu S, Liu YH, Wang LJ, Jing CX, Zeng FF

OBJECTIVE: There has been growing body of literatures showing that chronic inflammation might play an important role in cancer development. This meta-analysis aimed to assess the association between the dietary...
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Sentinel lymph node mapping in endometrial and cervical cancer: a survey of practices and attitudes in gynecologic oncologists

Chambers L, Vargas R, Michener C

OBJECTIVE: To determine patterns among gynecologic oncologists in sentinel lymph node mapping (SLNM) for endometrial cancer (EC) and cervical cancer (CC). METHODS: A online survey assessing the practice of SLNM, including...
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Prospective study of the efficacy and utility of TP53 mutations in circulating tumor DNA as a non-invasive biomarker of treatment response monitoring in patients with high-grade serous ovarian carcinoma

Kim YM, Lee SW, Lee YJ, Lee HY, Lee JE, Choi EK

OBJECTIVE: Somatic TP53 mutation (TP53mut ) is a characteristic finding in high-grade serous ovarian cancer (HGSOC). The aim of this study was to assess the clinical efficacy and utility of TP53mut circulating...
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Combined estrogen-progestin pill is a safe and effective option for endometrial hyperplasia without atypia: a three-year single center experience

Wang Y, Nisenblat , Tao L, Zhang X, Li H, Ma C

OBJECTIVE: To evaluate the effectiveness of oral contraceptive pill (OCP) as therapy for endometrial hyperplasia (EH) without atypia in reproductive-aged women compared with oral progestin. METHODS: A retrospective cohort study was...
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Survival outcomes of adjuvant radiotherapy and chemotherapy in women with stage I serous papillary and clear cell carcinoma of the endometrium: a Korean multicenter study

Kim M, Kwon BS, Chang HK, Lee S, Chang SJ, Choi JY, Park SY, Lee M, Ryu HS, Kim YB

OBJECTIVE: To compare the survival outcomes of adjuvant radiotherapy and chemotherapy in women with uterine-confined endometrial cancer with uterine papillary serous carcinoma (UPSC) or clear cell carcinoma (CCC). METHODS: Medical records...
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A multi-institutional analysis of sequential versus ‘sandwich’ adjuvant chemotherapy and radiotherapy for stage IIIC endometrial carcinoma

Onal C, Sari SY, Yildirim B, Yavas G, Gultekin M, Guler OC, Akyurek S, Yildiz F

OBJECTIVE: To analyze the outcomes of sequential or sandwich chemotherapy (ChT) and radiotherapy (RT) in patients with node-positive endometrial cancer (EC). METHODS: Data from 4 centers were collected retrospectively for 179...
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Feasibility and outcome of total laparoscopic radical hysterectomy with no-look no-touch technique for FIGO IB1 cervical cancer

Kanao H, Matsuo K, Aoki Y, Tanigawa T, Nomura H, Okamoto S, Takeshima

OBJECTIVES: Intraoperative tumor manipulation and dissemination may possibly compromise survival of women with early-stage cervical cancer who undergo minimally-invasive radical hysterectomy (RH). The objective of the study was to examine...
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Risk of cervical dysplasia among human papillomavirus-infected women in Korea: a multicenter prospective study

Park Y, Kim TJ, Hwang CS, Cho CH, Jeong DH, Seong SJ, Lee JK, Hur S, Kee MK, Seong J, Ki M

OBJECTIVE: Human papillomavirus (HPV) infection is the most important risk factor for cervical cancer, which progresses from precursor lesions with no symptom if left untreated. We compared the risk of...
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Reproductive counseling and pregnancy outcomes after radical trachelectomy for early stage cervical cancer

Shah JS, Jooya ND, Woodard TL, Ramirez PT, Fleming ND, Frumovitz

OBJECTIVE: To evaluate patient perceptions of preoperative reproductive counseling and to evaluate complications and pregnancy outcomes in women who had radical trachelectomy (RT) for early stage cervical cancer. METHODS: Patients who...
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A randomized trial comparing limited-excision conisation to Large Loop Excision of the Transformation Zone (LLETZ) in cervical dysplasia patients

Kolben TM, Etzel LT, Bergauer F, Hagemann I, Hillemanns P, Repper M, Kaufmann A, Sotlar K, Kolben T, Helms HJ, Gallwas J, Mahner S, Dannecker

OBJECTIVE: To show noninferiority of a limited-excision (resection of the dysplastic lesion only) vs. classical Large Loop Excision of the Transformation Zone (LLETZ). METHODS: In this prospective, randomized, multicenter trial, women...
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Preoperative chemoradiation followed by hysterectomy for cervical cancer: patterns of care and survival in a large, hospital database

Albert A, Allbright , Lee A, Vijayakumar S

OBJECTIVE: Adjuvant hysterectomy following chemoradiation (CRT) is a treatment option used worldwide for early-stage cervical cancer but the benefit of hysterectomy in this setting is unclear. An analysis of the...
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Incidence and costs of cervical intraepithelial neoplasia in the Korean population

Chang HK, Seo SS, Myong JP, Yu YL, Byun SW

OBJECTIVE: The purpose of this study was to assess the incidence rate of cervical intraepithelial neoplasia (CIN) and cervical cancer, and their costs according to age. METHODS: We collected data on...
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Perioperative morbidity of radical trachelectomy with lymphadenectomy in early-stage cervical cancer: a French prospective multicentric cohort

Balaya V, Lécuru F, Magaud L, Ngô C, Huchon C, Bats AS, Mathevet P

OBJECTIVE: The aim of this study was to determine the predictive factors of postoperative morbidity of patients who have undergone a radical trachelectomy (RT) for early-stage cervical cancer and to...
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PCR-reverse dot blot human papillomavirus genotyping as a primary screening test for cervical cancer in a hospital-based cohort

Kang Y, Sun P, Mao X, Dong B, Ruan G, Chen L

OBJECTIVE: To evaluate the polymerase chain reaction (PCR)-reverse-dot-blot (RDB) human papillomavirus (HPV) genotyping test as a feasible assay for the cervical cancer primary screening. METHODS: In a hospital-based cohort, a total...
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Improving pregnancy outcomes in fertility preserved cervical cancer patients: big challenge after radical trachelectomy

Li J

No abstract available.
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Adjuvant hysterectomy in patients with locally advanced cervical cancer treated with concurrent chemoradiotherapy

Shim SH

No abstract available.
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