J Gynecol Oncol.  2019 May;30(3):e37. 10.3802/jgo.2019.30.e37.

Incidence and costs of cervical intraepithelial neoplasia in the Korean population

• Chang HK
• Seo SS
• Myong JP
• Yu YL
• Byun SW

• KMID: 2440506
• DOI: http://doi.org/10.3802/jgo.2019.30.e37

Abstract

OBJECTIVE
The purpose of this study was to assess the incidence rate of cervical intraepithelial neoplasia (CIN) and cervical cancer, and their costs according to age.
METHODS
We collected data on annual incidence and medical costs of CIN and cervical cancer from 2010 until the end of 2014 from the Health Insurance Review and Assessment (HIRA) service. The CIN was classified into CIN3 (high-grade) requiring conization and CIN1/2 (low-grade) requiring observation.
RESULTS
Incidence rates of CIN3 and cervical cancer are reducing over time, whereas CIN1/2 is increasing significantly (p for trend: < 0.001). The peak ages of incidence were 25-29, 30-34, and 70-74 years old for CIN1/2, CIN3, and cervical cancer, respectively. The crude incidence of CIN1/2 increased by approximately 30% in 2014 compared to 5 years ago and demonstrated an increasing trend in all age groups. The CIN3 showed a significantly increasing trend in the age group of 30-39 years old, the cervical cancer was significantly reduced in all ages, except the 35-39 years old. The treatment for cervical cancer costs $3,342 per year, whereas the treatment for CIN3 and CIN1/2 cost $467 and $83, respectively.
CONCLUSION
The crude incidence rate of cervical cancer is currently decreasing among Korean women, but the incidence rates and medical costs of CIN and cervical cancer are increasing in women in their 30s in Korea. These findings suggest that different strategies by age will be required for prevention of cervical cancer in Korea.

Keyword

Incidence; Cost; Cervical intraepithelial neoplasia; Cervical cancer

MeSH Terms

Cervical Intraepithelial Neoplasia*
Conization
Female
Humans
Incidence*
Insurance, Health
Korea
Uterine Cervical Neoplasms