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A Case of Gerstmann-Straussler-Scheinker Disease

Park MJ, Jo HY, Cheon SM, Choi SS, Kim YS, Kim JW

BACKGROUND: Gerstmann-Straussler-Scheinker disease (GSS) is a type of human transmissible spongiform encephalopathy (TSE) that is determined genetically. CASE REPORT: A 46-year-old woman presented with a slowly progressive ataxic gait and cognitive...
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Benign Oligemia Despite a Malignant MRI Profile in Acute Ischemic Stroke

Bang OY, Lee KH, Kim SJ, Liebeskind DS

BACKGROUND: It has recently been suggested that diffusion and perfusion MRI can identify subgroups likely to benefit or potentially be harmed by reperfusion therapies. CASE REPORT: We investigated serial MRI data...
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Early Dorsal Midbrain Syndrome Mimicking an Adie's Tonic Pupil

Han SW, Ryu JH, Baik JS, Kim JY, Hwang YS, Park JH

BACKGROUND: While tonic pupils have been attributed to various diseases, including syphilis, herpes zoster, orbital trauma, temporal arteritis, endometriosis, and paraneoplastic syndromes, obstructive hydrocephalus has not been implicated. CASE REPORT: A...
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Diagnostic Value of Cerebrospinal Fluid Level of Carcinoembryonic Antigen in Patients with Leptomeningeal Carcinomatous Metastasis

Kang SJ, Kim KS, Ha YS, Huh SY, Lee JH, Kim JK, Kim MJ

BACKGROUND AND PURPOSE: Multifocal seeding of the leptomeninges by malignant cells, which is usually referred to as leptomeningeal carcinomatous metastasis, produces substantial morbidity and mortality. The diagnosis of leptomeningeal metastasis...
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Frovatriptan is Effective and Well Tolerated in Korean Migraineurs: A Double-Blind, Randomized, Placebo-Controlled Trial

Moon HS, Chu MK, Park JW, Oh K, Chung JM, Cho YJ, Kim EG, Do JK, Jung HG, Kwon SU

BACKGROUND AND PURPOSE: Frovatriptan is a selective 5-HT1B/1D agonist with a long duration of action and a low incidence of side effects. Although several placebo-controlled trials have documented the clinical...
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Can Early Ischemic Lesion Recurrence on Diffusion-Weighted MRI Affect Functional Outcome after Acute Ischemic Stroke?

Kim WJ, Kim JH, Ko Y, Park JH, Yang MH, Jang MS, Han MK, Kim SY, Park SH, Bae HJ

BACKGROUND AND PURPOSE: Ischemic lesion recurrence on diffusion-weighted imaging (DWI-LR) is a frequently observed phenomenon after acute ischemic stroke. However, no study has elucidated the impact of DWI-LR on functional...
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Will Molecular Optical Imaging Have Clinically Important Roles in Stroke Management, and How?

Lee DK, Nahrendorf M, Schellingerhout D, Kim DE

Molecular imaging is a novel technology to visualize biological processes at the cellular and molecular levels, which is reshaping both biomedical research and clinical practice. By providing molecular information to...
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Cerebral Autosomal Dominant Arteriopathy with Subcortical Infarcts and Leukoencephalopathy: A Genetic Cause of Cerebral Small Vessel Disease

Choi JC

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a single-gene disorder of the cerebral small blood vessels caused by mutations in the Notch3 gene. The exact prevalence...
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