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The First Case of Non-retrospective Clinical Identification of Severe Fever with Thrombocytopenia Syndrome Patient in 2013 in South Korea

Heo ST, Yoo JR, Lee KH, Ko KS

In this study, we report the first clinically identified case of severe fever with thrombocytopenia syndrome (SFTS) in a 73-year old man from Jeju Island, South Korea. Although his initial...
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Glycopeptide Antibiotics: Structure and Mechanisms of Action

Kang HK, Park Y

Glycopeptides of the clinically important antibiotic drugs are glycosylated cyclic or polycyclic nonribosomal peptides. Glycopeptides such as vancomycin and teicoplanin are often used for the treatment of gram-positive bacteria in...
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Carnobacterium Isolated from Caviar of Sturgeon (Acipenser ruthenus) Farmed in Korea

Kim D, Kang K, Cheon H, Im J, Park K

Sturgeon aqua-cultured in Korea is mainly Acipenser ruthenus and its culture began in the early 2000's. In this study, Carnobacterium sp. was isolated from unprocessed caviar of aqua-cultured Acipenser ruthenus....
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Reoviral Oncotropism Against c-Myc Overexpressing HS 68 Cells

Kim M

Naturally occurring reoviruses are live replication-proficient viruses specifically infecting human cancer cell while sparing normal counterpart. Since the discovery of reoviruses in 1950s, reoviruses have shown various degrees of safety...
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The Applications of Hepatitis C Virus (HCV) Replication System in Developing Anti-HCV Reagents

Cho H

Hepatitis C virus (HCV) is known to be a major cause of chronic hepatitis, liver cirrhosis and hepatocarcinoma. Therapeutic reagents are improving, but are still limited, and the protective vaccine...
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Contribution of Periodontal Disease in Atherosclerosis

Na HS, Chung J

Periodontitis is a disease that leads to destruction of the soft and hard tissues of periodontium, which can result in periodontal bone loss and tooth loss in severe cases. Atherosclerosis...
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Differential Regulation of NF-kappaB Signaling during Human Cytomegalovirus Infection

Kwon KM, Ahn JH

NF-kappaB transcription factors are key regulators of immune and stress responses, apoptosis, and differentiation. Human cytomegalovirus (HCMV) activates or represses NF-kappaB signaling at different times during infection. An initial increase...
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Seroreactive Mycobacterial Proteins and Lipid in Cattle with Bovine Tuberculosis

Jeon HS, Shin AR, Son YJ, Kim JM, Jang Y, Kim S, Lee KI, Choi CH, Park JK, Kim HJ

Bovine tuberculosis caused by Mycobacterium bovis is a major economic problem in several countries. Antibody responses are useful indicators of M. bovis infection of cattle. To overcome drawback of serological...
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Probiotics Used for Respiratory Diseases

Shin Y, Kim T, Kim K

Continuous increase of bacterial resistance to antibiotics causes many problems such as the advent of resistance to pathogenic bacteria, difficulty of microbial disease treatments, environmental pollution and others. It is...
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Molecular Epidemiology of Mumps Virus Circulated in Gwangju

Kim SH, Seo M, Park JW, Cho SJ, Ha YD, Ha DR, Kim ES, Kang HJ, Kim SS, Kim K, Chung JK

The recent mumps epidemic in South Korea has generated a large amount of public concern. This study has attempted to analyze molecular epidemiological changes of mumps virus circulating in Gwangju...
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Molecular Characterization of Community-Associated Methicillin-Resistant and Methicillin-Susceptible Staphylococcus aureus Isolates from Children with Skin Infections in Busan, Korea

Park SH, Kim KJ, Kim BK, Hwang SM

The prevalence and molecular characteristics of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) and methicillin-susceptible S. aureus (CA-MSSA) from children with skin infection were investigated by staphylocoagulase (SC) typing, multilocus sequence typing...
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Interleukin-1beta Participates in the Development of Pneumococcal Acute Lung Injury and Death by Promoting Alveolar Microvascular Leakage

Bong Y, Shin SG, Koh SH, Lim JH

Streptococcus pneumoniae (S. pneumoniae, also known as pneumococcus) infections are major causes of death worldwide. Despite the development and use of effective antibiotics, high, early mortality due to pneumococcal infections...
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CCL5 Inhibits Elevation of Blood Pressure and Expression of Hypertensive Mediators in Developing Hypertension State Spontaneously Hypertensive Rats

Kim HY, Cha HJ, Choi JH, Kang YJ, Park SY, Kim HS

CCL5, a proinflammatory chemokine, has been shown to attenuate angiotensin (Ang) II-induced expression of hypertensive mediators as well as Ang II-induced inhibition of anti-hypertensive mediator expression in vascular smooth muscle...
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