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Role of Cyclic GMP-AMP Synthase in Sensing Human Immunodeficiency Virus

Park YS, Kim IH, Koh YS

Cyclic guanosine monophosphate adenosine monophosphate (cGAMP) synthase (cGAS) detects human immunodeficiency virus (HIV) and produces cGAMP to induce cytokines. Reverse transcribed DNA of HIV is critical for triggering innate immune...
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Performance Comparison of Benchtop Next-generation Sequencing Systems

Na HS

With fast development and wide applications of next generation sequencing (NGS), genomic sequence information is within reach to various research fields. Three benchtop NGS instruments are now available. The 454...
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Mechanism of Action of Antimicrobial Peptides Against Bacterial Membrane

Lee JK, Park Y

Resistance to antibiotics is becoming a very serious problem, with so-called superbugs exhibiting resistance to nearly all conventional antibiotic drugs. Consequently, these organisms often cause severe illness and even death....
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Microbial Profile of the Stomach: Comparison between Normal Mucosa and Cancer Tissue in the Same Patient

Seo I, Jha BK, Suh SI, Suh MH, Baek WK

Gastric cancer is the third most common cancer and the third most frequent cause of cancer mortality in Asia. It is predicted that gastric cancer will remain an important cause...
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Aspergillus oryzae S-03 Produces Gingipain Inhibitors as a Virulence Factor for Porphyromonas gingivalis

Danshiitsoodol N, Yamashita , Noda M, Kumagai T, Matoba Y, Sugiyama M

Oral infection with Porphyromonas (P.) gingivalis causes periodontitis that is manifested by the destruction of gingival connective tissues. Although a few types of antibiotics are effective against the infection, its...
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Genome Size Constraint in Replication and Packaging of Turnip Yellow Mosaic Virus

Kim HB, Chae KH, Cho TJ

Turnip yellow mosaic virus (TYMV) is a spherical plant virus that has a single 6.3 kb positive strand RNA as a genome. Previously, we have made the recombinant TYMV construct...
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Molecular Epidemiology of Clostridium perfringens Isolated from Food Poisoning in Seoul, 2013

Jin Y, Jung J, Jeon S, Choi S, Kim Y, Oh Y, Choi S, Jung K

Clostridium perfringens food poisoning ranks among the most common gastrointestinal diseases in developed countries. In Korea, C. perfringens food poisoning gradually increases. Using PCR, 72 strains of C. perfringens isolated...
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Proteome Analysis of a Catalase-deficient Isogenic Mutant of Helicobacter pylori 26695

Kang HL, Lee SG, Park JS, Song JY, Cho MJ, Baik SC, Youn HS, Seo JH, Rhee KH, Lee WK

Helicobacter pylori, a gram-negative bacterium, is a causative agent of gastroduodenal diseases of human. Human immune system produces harmful reactive oxygen species to kill this bacterium that locates the microaerophilic...
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Host Immune Responses Against Type A Influenza Viruses

Cho H, Kang H

The influenza viruses are divided into 3 different types, A, B and C, all of them are known as human pathogens. However, only type A influenza viruses cause both epidemic...
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The in vivo and in vitro Roles of Epithelial Pattern Recognition Receptors in Pneumococcal Infections

Shin SG, Koh SH, Lim JH

Streptococcus pneumoniae, also called pneumococcus, is a major cause of infectious disease in human. Pneumococcus resides in the nasopharynx as an upper respiratory commensal, and most of pneumococcal colonizations are...
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The Molecular Epidemiology of Circulating Group A Rotavirus in Gwangju Metropolitan City, Korea: 2008~2012

Kee HY, Kim MJ, Kim SH, Ha DR, Kim ES, Jeong HS, Chung JK, Lee BJ

Group A rotaviruses are a major cause of acute gastroenteritis in young children worldwide. For the proper management of rotavirus infections, knowledge of the distribution of G and P genotypes...
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