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Staphylococcus aureus Membrane Vesicles and Its Potential Role in Bacterial Pathogenesis

Lee JC

The production of extracellular vesicles is a ubiquitous process in both Gram-negative and Gram-positive bacteria. Gram-negative bacteria produce and secrete outer membrane vesicles during in vitro culture and in vivo...
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Endoplasmic Reticulum Stress Responses and Apoptosis

Song CH

The endoplasmic reticulum (ER) plays a crucial role in various cellular activities and cell survival. Almost all of the resident proteins usually enter the ER, and are modified with N-linked...
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Mitogen-activated Protein Kinases in Inflammation

Manzoor Z, Koh YS

Mitogen-activated protein kinases (MAPKs) play critical regulatory roles in the production of the pro-inflammatory cytokines and downstream signaling events which lead to inflammation. Inflammation is a primarily localized and protective...
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Toll-Like Receptor Ligands as Cancer Immunotherapeutics

Lee SE, Rhee JH

Toll-like receptors (TLRs) are pattern recognition receptors (PRRs) expressed in a wide spectrum of cell types that recognize distinctive ligands and subsequently activate adaptive immune responses. TLR ligands are considered...
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RNA Granules and Stress Granules in Virus Systems

Kim K

Viruses initiate a number of cellular stress responses and modulate gene regulation and compartmentalization of RNA upon infection to be successful parasites. Virus infections may induce or impair stress granule...
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Antibody Response in Korean Raccoon Dogs Inoculated with Inactivated Rabies Vaccines

Yang DK, Go TO, Nam YH, Kim HH, Cho SD, Lee KW, Choi SS, Song JY

Since sylvatic rabies was first identified in South Korea in 1993, over three million bait vaccine doses have been distributed to rabies risk regions in order to block transmission of...
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Epidemiological Study of Ground-waterborne Norovirus GI.3-associated Gastroenteritis Outbreaks in Gyeonggi Province of South Korea in May 2011

Lee MJ, Kim WH, Cho HG, Lee SS

In May 2011, five consecutive gastroenteritis outbreaks were reported at schools in Gyeonggi-do. Epidemiological inspection revealed that one food manufacture company provided 'Kimchi', a traditional Korean side-dish, to these five...
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Proteomic Analysis of Thiol-active Proteins of Helicobacter pylori 26695

Park JW, Song JY, Hwang HR, Park HJ, Youn HS, Seo JH, Kang HL, Lee KH, Baik SC, Lee WK, Cho MJ, Rhee KH

Helicobacter pylori are a capnophilic bacterium, which colonize gastric mucosa and are resistant to acidic and oxidative damage. Thiol-active proteins subserve redox functions in tolerating oxidative stress and environmental toxicants,...
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Adenovirus Expressing Human Interferon Inhibits Replication of Foot and Mouth Disease Virus and Reduces Fatal Rate in Mice

Chu JQ, Kim SM, Lee KN, Oem JK, Ko YJ, Lee HS, Kim YJ, Park JY, Kim KJ, Parida S, Oh Y, Paton DJ, Joo YS, Kim B, Park JH

Interferon is an important cytokine that plays a critical role in the initial host defense against viral infection. Recombinant human adenoviruses expressing human interferon-alpha (Ad-HIFNalpha) or pig interferon-beta fused with...
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Mutations in gyrA and parC Genes and Plasmid-Mediated Quinolone Resistance in Non-typhoid Salmonella Isolated from Pediatric Patients with Diarrhea in Seoul

Jin YH, Jung JH, Jeon SJ, Lee JK, Oh YH, Choi SM, Chae YZ

A total of 91 non-typhoid Salmonella isolated from pediatric patients with diarrhea in Seoul from 2003 to 2009 was tested for antimicrobial susceptibility of nalidixic acid (NA). Forty strains of...
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