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Age-associated changes in pancreatic exocrine secretion of the isolated perfused rat pancreas

Jiang ZE, Jiang C, Chen B, Koh CS, Yong JH, Park DH, Won MH, Lee YL

Gut functions, such as gastrointestinal motility, gastric secretion and pancreatic secretion, were reduced with age. Glucose tolerance is impaired, and the release of insulin and beta-cell's sensitivity on glucose are...
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Successful salvage treatment of acute graft-versus-host disease after liver transplantation by withdrawal of immunosuppression: a case report

Qiu W, Lv GY, Jiang C, Zhang P, Sun XD, Shi XJ, Liu XY, Wang GY

Acute graft-versus-host disease (GVHD) following liver transplantation is a rare but fatal complication. The correct diagnosis and management of GVHD after liver transplantation are still major challenges. Herein, we reported...
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Investigation of morphological changes of HPS membrane caused by cecropin B through scanning electron microscopy and atomic force microscopy

Hu H, Jiang C, Zhang B, Guo N, Li Z, Guo X, Wang Y, Liu B, He Q

Background Antimicrobial peptides (AMPs) have been identified as promising compounds for consideration as novel antimicrobial agents. Objectives This study analyzed the efficacy of cecropin B against Haemophilus parasuis isolates through scanning electron microscopy...
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IL-34 Aggravates Steroid-Induced Osteonecrosis of the Femoral Head via Promoting Osteoclast Differentiation

Wang F, Min HS, Shan H, Yin F, Jiang C, Zong Y, Ma X, Lin Y, Zhou Z, Yu X

IL-34 can promote osteoclast differentiation and activation, which may contribute to steroidinduced osteonecrosis of the femoral head (ONFH). Animal model was constructed in both BALB/c and IL-34 deficient mice to...
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Exploring differentially expressed genes related to metabolism by RNASeq in porcine embryonic fibroblast after insulin treatment

Liang Y, Wang J, Li X, Wu S, Jiang C, Wang Y, Li X, Liu ZH, Mu Y

Background: Insulin regulates glucose homeostasis and has important effects on metabolism, cell growth, and differentiation. Depending on the cell type and physiological context, insulin signal has specific pathways and biological...
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Psychosocial Factors Associated With Irritable Bowel Syndrome Development in Chinese College Freshmen

Jiang C, Xu Y, Sharma S, Zhang L, Wang H, Song J, Qian W, Bai T, Hou X

  • KMID: 2449095
  • J Neurogastroenterol Motil.
  • 2019 Apr;25(2):233-240.
  • doi: 10.5056/jnm18028
BACKGROUND/AIMS: The role of psychosocial factors on irritable bowel syndrome (IBS) in adolescents is incompletely understood. The aim of this study is to investigate the association between the psychosocial factors...
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AITC induces MRP1 expression by protecting against CS/CSE-mediated DJ-1 protein degradation via activation of the DJ-1/Nrf2 axis

Xu L, Wu J, Li N, Jiang C, Guo Y, Cao P, Wang D

The present study aimed to examine the effect of allyl isothiocyanate (AITC) on chronic obstructive pulmonary disease and to investigate whether upregulation of multidrug resistance-associated protein 1 (MRP1) associated with...
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Accurate transfer of bimaxillary orthognathic surgical plans using computer-aided intraoperative navigation

Chen C, Sun N, Jiang C, Liu Y, Sun J

Objective: To examine the accuracy of computer-aided intraoperative navigation (Ci-Navi) in bimaxillary orthognathic surgery by comparing preoperative planning and postoperative outcome. Methods: The study comprised 45 patients with congenital dentomaxillofacial deformities...
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Isoperistaltic side-to-side anastomosis for the surgical treatment of Crohn disease

Chen W, Zhou J, Chen M, Jiang C, Qian Q, Ding Z

Purpose: Increasing evidence has shown an association of surgical technique, particularly anastomotic configuration, with postoperative recurrence of CD. This pilot study aimed to evaluate short-term outcomes of isoperistaltic side-to-side anastomosis...
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Ameliorative effects of atractylodin on intestinal inflammation and co-occurring dysmotility in both constipation and diarrhea prominent rats

Yu C, Xiong Y, Chen D, Li Y, Xu B, Lin Y, Tang Z, Jiang C, Wang L

Intestinal disorders often co-occur with inflammation and dysmotility. However, drugs which simultaneously improve intestinal inflammation and co-occurring dysmotility are rarely reported. Atractylodin, a widely used herbal medicine, is used to...
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Mutant IDH1 Enhances Temozolomide Sensitivity via Regulation of the ATM/CHK2 Pathway in Glioma

Lin L, Cai J, Tan Z, Meng X, Li R, Li Y, Jiang C

Purpose Isocitrate dehydrogenase 1 (IDH1) mutations are the most common genetic abnormalities in low-grade gliomas and secondary glioblastomas. Glioma patients with these mutations had better clinical outcomes. However, the effect of...
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The Physiological Occlusion of the Central Canal May Be a Prerequisite for Syringomyelia Formation

Jiang C, Wang X, Lu C, Li Q, Ma L, Li W, Cui S, Li K, Wang X, Feng Y, Jian F

Objective: Syringomyelia is a common central nervous system disease characterized by the dilation of the central canal (CC). Regarding the pathogenesis of syringomyelia, cerebrospinal fluid (CSF) circulation obstruction in the...
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Potential Biomarker of L-type Amino Acid Transporter 1 in Breast Cancer Progression

Liang Z, Cho HT, Williams L, Zhu A, Liang K, Huang K, Wu H, Jiang C, Hong S, Crowe R, Goodman MM, Shim H

  • KMID: 2313132
  • Nucl Med Mol Imaging.
  • 2011 Jun;45(2):93-102.
PURPOSE: L-type amino acid transporter 1 (LAT1) is essential for the transport of large neutral amino acids. However, its role in breast cancer growth remains largely unknown. The purpose of...
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Inhibition of microRNA-214 promotes epithelial–mesenchymal transition process and induces interstitial cystitis in postmenopausal women by upregulating Mfn2

Lv JW, Wen W, Jiang C, Fu QB, Gu YJ, Lv TT, Li ZD, Xue W

Our study aims to investigate the roles that microRNA-214 (miR-214) plays in the epithelial mesenchymal transition (EMT) process and the development of interstitial cystitis (IC) in postmenopausal women by targeting...
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