- Transient Myocardial Ischemia during General Anesthesia with Isoflurane: Case report
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Kim HJ, Park KH, Choi HY, Jhun JY
- KMID: 2154498
- Korean J Anesthesiol.
- 1997 Nov;33(5):974-978.
- doi: 10.4097/kjae.1997.33.5.974
Myocardial ischemia occurs when myocardial oxygen availability is inadequate to meet metabolic requirements. The common cause of myocardial ischemia is atherosclerotic epicardial coronary arteries. Isoflurane is a potent small vessel-type... -
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- Identification and comparison of functional microbiomes affecting immune homeostasis in long-term stable and tolerant patients after liver transplantation
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Lee SK, Jhun JY, Cho ML, Choi HJ, You YK, Sung PS, Jang JW, Yoon SK, Choi JY
- KMID: 2535649
- Korean J Transplant.
- 2022 Nov;36(Supple 1):S133.
- doi: 10.4285/ATW2022.F-2532
Background: In this study, we aimed to identify the gut microbial balance and functional microbiomes affecting immune homeostasis in the long-term post-liver transplant (LT) and tolerant patients. Methods: A total of... -
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- Metformin ameliorates experimental-obesity-associated autoimmune arthritis by inducing FGF21 expression and brown adipocyte differentiation
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Kim EK, Lee SH, Lee SY, Kim JK, Jhun JY, Na HS, Kim SY, Choi JY, Yang CW, Park SH, Cho ML
- KMID: 2438362
- Exp Mol Med.
- 2018 Jan;50(1):e432.
- doi: 10.1038/emm.2017.245
Rheumatoid arthritis (RA) is a systemic autoimmune disease involving excessive inflammation. Recently, RA associated with a metabolic disorder was revealed to be non-responsive to RA medications. Metformin has been reported... -
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- The Marginal Zone B Cells have an Increased Antibody Expression in Mice with Collagen-induced Arthritis
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Woo YJ, Min JK, Cho ML, Kim YJ, Jhun JY, Park MJ, Moon YM, Park MK, Kim HY
- KMID: 2202137
- J Korean Rheum Assoc.
- 2009 Mar;16(1):23-32.
- doi: 10.4078/jkra.2009.16.1.23
OBJECTIVE: Mature B cells in the spleen of mouse can be divide into two main subsets: the follicular (FO) B cells and the marginal zone (MZ) B cells. In this... -
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- Anti-CD3 Antibody Induces IL-10-producing CD4+CD25+ Regulatory T Cells, Which Suppress T Cell Response in Rheumatoid Arthritis Patients
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Yoon BY, Cho ML, Hong YS, Jhun JY, Park MK, Park KS, Park SH, Kim HY
- KMID: 1513198
- Immune Netw.
- 2007 Sep;7(3):124-132.
- doi: 10.4110/in.2007.7.3.124
BACKGROUND: Regulatory T cells (Tregs) have been investigated intensively for some decades. These cells regulate the immune system, prevent overactivated immune responses and can be used therapeutically. For rheumatoid arthritis... -
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- Characterization of FSC(high) Memory B Cells from Patients with Active Systemic Lupus Erythematosus
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Jhun JY, Kim YJ, Ju JH, Park SH, Chang SH, Kim HY
- KMID: 2202170
- J Korean Rheum Assoc.
- 2007 Sep;14(3):219-226.
- doi: 10.4078/jkra.2007.14.3.219
OBJECTIVE: To determine phenotypic and functional characteristics of memory B cells in patients with systemic lupus erythematosus (SLE). METHODS: The percentage of memory B cell subsets in peripheral blood mononuclear... -
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- Ursodeoxycholic Acid Ameliorates Pain Severity and Cartilage Degeneration in Monosodium Iodoacetate-Induced Osteoarthritis in Rats
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Moon SJ, Jeong JH, Jhun JY, Yang EJ, Min JK, Choi JY, Cho ML
- KMID: 1508828
- Immune Netw.
- 2014 Feb;14(1):45-53.
- doi: 10.4110/in.2014.14.1.45
Osteoarthritis (OA) is a degenerative joint disease characterized by a progressive loss of cartilage. And, increased oxidative stress plays a relevant role in the pathogenesis of OA. Ursodeoxycholic acid (UDCA)... -
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- Interleukin-17 Enhances Germinal Center Formation and Immunoglobulin G1 Production in Mice
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Lee J, Lee SY, Kang CM, Jhun JY, Kim JH, Cho ML, Park SH, Kim HY, Kwok SK
- KMID: 2394342
- J Rheum Dis.
- 2017 Oct;24(5):271-278.
- doi: 10.4078/jrd.2017.24.5.271
OBJECTIVE: Interleukin (IL)-17 is a pro-inflammatory cytokine that has pleiotropic effects on multiple target cells and thereby contributes to the development of immune-mediated inflammatory disorders. However, the role of IL-17... -
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- Regulation of B cell activating factor (BAFF) receptor expression by NF-kappaB signaling in rheumatoid arthritis B cells
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Woo YJ, Yoon BY, Jhun JY, Oh HJ, Min S, Cho ML, Park SH, Kim HY, Min JK
- KMID: 1107376
- Exp Mol Med.
- 2011 Jun;43(6):350-357.
- doi: 10.3858/emm.2011.43.6.038
B cells play an important role in the pathogenesis of rheumatoid arthritis (RA). High levels of B cell activating factor (BAFF) are detected in autoimmune diseases. BAFF and BAFF receptor... -
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- Obesity aggravates the joint inflammation in a collagen-induced arthritis model through deviation to Th17 differentiation
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Jhun JY, Yoon BY, Park MK, Oh HJ, Byun JK, Lee SY, Min JK, Park SH, Kim HY, Cho ML
- KMID: 1397446
- Exp Mol Med.
- 2012 Jul;44(7):424-431.
White fat cells secrete adipokines that induce inflammation and obesity has been reported to be characterized by high serum levels of inflammatory cytokines such as IL-6 and TNF-alpha. Rheumatoid arthritis... -
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- Expression of CCR2A, an isoform of MCP-1 receptor, is increased by MCP-1, CD40 ligand and TGF-beta in fibroblast like synoviocytes of patients with RA
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Cho ML, Yoon BY, Ju JH, Jung YO, Jhun JY, Park MK, Park SH, Cho CS, Kim HY
- KMID: 756073
- Exp Mol Med.
- 2007 Aug;39(4):499-507.
Cytokine and chemokine receptors play a key role in inflammation caused by rheumatoid arthritis (RA). Two isoforms of human CC chemokine receptor R2 (CCR2), the receptor of monocyte chemoattractant protein... -
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- Grape seed proanthocyanidin extract ameliorates monosodium iodoacetate-induced osteoarthritis
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Woo YJ, Joo YB, Jung YO, Ju JH, Cho ML, Oh HJ, Jhun JY, Park MK, Park JS, Kang CM, Sung MS, Park SH, Kim HY, Min JK
- KMID: 1123368
- Exp Mol Med.
- 2011 Oct;43(10):561-570.
- doi: 10.3858/emm.2011.43.10.062
Osteoarthritis (OA) is an age-related joint disease that is characterized by degeneration of articular cartilage and chronic pain. Oxidative stress is considered one of the pathophysiological factors in the progression... -
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