- Differentiation characteristics of cholesteatoma epithelium determined by expression of transglutaminase isoenzymes
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Chang CS, Jun BH, Song KY, Kim IG
- KMID: 646044
- J Korean Med Sci.
- 1999 Dec;14(6):665-670.
- doi: 10.3346/jkms.1999.14.6.665
Transglutaminase (TGase) isoenzymes are involved in the process of the differentiation and cornification of keratinocytes in the epidermis. This study investigates the presence and localization of three TGase isoenzymes to... -
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- Isozyme electrophoresis patterns of the liver fluke, Clonorchis sinensis from Kimhae, Korea and from Shenyang, China
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Park GM, Yong TS, Im K, Lee KJ
- KMID: 1040998
- Korean J Parasitol.
- 2000 Mar;38(1):45-48.
- doi: 10.3347/kjp.2000.38.1.45
An enzyme analysis of the liver fluke, Clonorchis sinensis from Kimhae, Korea and from Shenyang, China was conducted using a horizontal starch gel electrophoresis in order to elucidate their genetic... -
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- A mutation in QRDR in the ParC subunit of topoisomerase IV was responsible for fluoroquinolone resistance in clinical isolates of Streptococcus pneumoniae
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Choi H, Lee HJ, Lee Y
- KMID: 711596
- Yonsei Med J.
- 1998 Dec;39(6):541-545.
- doi: 10.3349/ymj.1998.39.6.541
Forty-one strains of Streptococcus pneumoniae were isolated at Seoul National University Children's Hospital from 1991 to 1997. Isolates were divided into six groups based on MICs of three quinolones, ciprofloxacin,... -
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- Hypermethylation of Tumor-related Genes in Genitourinary Cancer Cell Lines
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Chung WB, Hong SH, Kim JA, Sohn YK, Kim BW, Kim JW
- KMID: 648358
- J Korean Med Sci.
- 2001 Dec;16(6):756-761.
- doi: 10.3346/jkms.2001.16.6.756
Hypermethylation of CpG island is a common mechanism for the inactivation of tumor-related genes. In the present study, we analyzed 13 genitourinary cancer cell lines for aberrant DNA methylation of... -
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- Decreased nitric oxide synthesis in rats with chronic renal failure
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Kim SW, Lee JU, Paek YW, Kang DG, Choi KC
- KMID: 1730639
- J Korean Med Sci.
- 2000 Aug;15(4):425-430.
- doi: 10.3346/jkms.2000.15.4.425
The present study was aimed at investigating whether an altered role of nitric oxide (NO) is involved in chronic renal failure (CRF). Rats were subjected to 5/6 nephrectomy and kept... -
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- Inhibitory effects of osteoprotegerin on osteoclast formation and function under serum-free conditions
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Fu YX, Gu JH, Zhang YR, Tong XS, Zhao HY, Yuan Y, Liu XZ, Bian JC, Liu ZP
- KMID: 1712306
- J Vet Sci.
- 2013 Dec;14(4):405-412.
- doi: 10.4142/jvs.2013.14.4.405
The purpose of this study was to determine whether osteoprotegerin (OPG) could affect osteoclat differentiation and activation under serum-free conditions. Both duck embryo bone marrow cells and RAW264.7 cells were... -
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- Rebamipide-induced downregulation of phospholipase D inhibits inflammation and proliferation in gastric cancer cells
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Kang DW, Min G, Park DY, Hong KW, Min DS
- KMID: 1104382
- Exp Mol Med.
- 2010 Aug;42(8):555-564.
- doi: 10.3858/emm.2010.42.8.056
Rebamipide a gastroprotective drug, is clinically used for the treatment of gastric ulcers and gastritis, but its actions on gastric cancer are not clearly understood. Phospholipase D (PLD) is overexpressed... -
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- Expression of integrins, cyclooxygenases and matrix metalloproteinases in three-dimensional human endometrial cell culture system
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Yang H, Han S, Kim H, Choi YM, Hwang KJ, Kwon HC, Kim SK, Cho DJ
- KMID: 1093601
- Exp Mol Med.
- 2002 Mar;34(1):75-82.
The objective of this investigation was to establish a three-dimensionally cultured human endometrium which could be used as a tissue model for the mechanism study of implantation in vitro. By... -
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- DNA Hypermethylation of Tumor-Related Genes in Gastric Carcinoma
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Hong SH, Kim HG, Chung WB, Kim EY, Lee JY, Yoon SM, Kwon JG, Sohn YK, Kwak EK, Kim JW
- KMID: 1095197
- J Korean Med Sci.
- 2005 Apr;20(2):236-241.
- doi: 10.3346/jkms.2005.20.2.236
The hypermethylation of the CpG islands is a common mechanism for the inactivation of tumor-related genes. In the present study, we analyzed the methylation status of genes for cell repair... -
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- Simvastatin inhibits osteoclast differentiation by scavenging reactive oxygen species
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Moon HJ, Kim SE, Yun YP, Hwang YS, Bang JB, Park JH, Kwon IK
- KMID: 1025163
- Exp Mol Med.
- 2011 Nov;43(11):605-612.
- doi: 10.3858/emm.2011.43.11.067
Osteoclasts, together with osteoblasts, control the amount of bone tissue and regulate bone remodeling. Osteoclast differentiation is an important factor related to the pathogenesis of bone-loss related diseases. Reactive oxygen... -
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- Multi-facet expressions of adenylate cyclase isoforms in B16-F10 melanoma cells differentiated by forskolin treatment
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Cho DH, Bae CD, Juhnn YS
- KMID: 755106
- Exp Mol Med.
- 2000 Dec;32(4):235-242.
The terminal differentiation of malignant melanoma cells is known to be induced by activating cAMP signaling pathway with alpha-MSH or cAMP analogues. However, sustained activation of cAMP signaling... -
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- Methyl-beta-cyclodextrin inhibits cell growth and cell cycle arrest via a prostaglandin E(2) independent pathway
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Choi YA, Chin BR, Rhee DH, Choi HG, Chang HW, Kim JH, Baek SH
- KMID: 755669
- Exp Mol Med.
- 2004 Feb;36(1):78-84.
Methyl-beta-cyclodextrin, a cyclic oligosaccharide known for its interaction with the plasma membrane induces several events in cells including cell growth and anti-tumor activity. In this study, we have investigated the... -
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- Regulation of glutamate level in rat brain through activation of glutamate dehydrogenase by Corydalis ternata
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Lee KH, Huh JW, Choi MM, Yoon SY, Yang SJ, Hong HN, Cho SW
- KMID: 1093472
- Exp Mol Med.
- 2005 Aug;37(4):371-377.
When treated with protopine and alkalized extracts of the tuber of Corydalis ternata for one year, significant decrease in glutamate level and increase in glutamate dehydrogenase (GDH) activity was observed... -
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