- Irritable bowel syndrome-like symptoms associated with endoscopic activity predict ulcerative colitis relapse in patients with clinical remission
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Fukuba N, Ishihara S, Kawashima , Mishima Y, Oshima N, Kinoshita
- KMID: 2396407
- Intest Res.
- 2017 Oct;15(4):543-545.
- doi: 10.5217/ir.2017.15.4.543
No abstract available. -
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- Essential anatomy for lateral lymph node dissection
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Yokoyama Y, Nozawa H, Sasaki K, Murono K, Emoto S, Matsuzaki H, Abe S, Nagai Y, Yoshioka Y, Shinagawa T, Sonoda H, Hojo D, Ishihara S
- KMID: 2549559
- Ann Coloproctol.
- 2023 Dec;39(6):457-466.
- doi: 10.3393/ac.2023.00164.0023
In Western countries, the gold-standard therapeutic strategy for rectal cancer is preoperative chemoradiotherapy (CRT) following total mesorectal excision (TME), without lateral lymph node dissection (LLND). However, preoperative CRT has recently... -
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- Neuroendocrine carcinoma associated with chronic ulcerative colitis: a case report and review of the literature
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Yokota Y, Anzai H, Nagai Y, Sonoda H, Shinagawa T, Yoshioka Y, Abe S, Yokoyama Y, Matsuzaki H, Emoto S, Murono K, Sasaki K, Nozawa H, Ushiku T, Ishihara S
- KMID: 2556094
- Ann Coloproctol.
- 2024 May;40(Suppl 1):S32-S37.
- doi: 10.3393/ac.2022.00801.0114
Adenocarcinoma is a common histological type of ulcerative colitis-associated cancer (UCAC), whereas neuroendocrine carcinoma (NEC) is extremely rare. UCAC is generally diagnosed at an advanced stage, even with regular surveillance... -
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- Risk factors for non-reaching of ileal pouch to the anus in laparoscopic restorative proctocolectomy with handsewn anastomosis for ulcerative colitis
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Emoto S, Hata K, Nozawa H, Kawai K, Tanaka T, Nishikawa T, Shuno Y, Sasaki K, Kaneko M, Murono K, Iida Y, Ishii H, Yokoyama Y, Anzai H, Sonoda H, Ishihara S
- KMID: 2531985
- Intest Res.
- 2022 Jul;20(3):313-320.
- doi: 10.5217/ir.2020.00158
Background/Aims: Restorative proctocolectomy (RPC) with ileal pouch-anal anastomosis and handsewn anastomosis for ulcerative colitis requires pulling down of the ileal pouch into the pelvis, which can be technically challenging. We... -
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- Advantages and Disadvantages of Long-term Proton Pump Inhibitor Use
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Kinoshita , Ishimura N, Ishihara S
- KMID: 2413095
- J Neurogastroenterol Motil.
- 2018 Apr;24(2):182-196.
- doi: 10.5056/jnm18001
Proton pump inhibitors (PPIs) potently inhibit gastric acid secretion and are widely used for treatment of acid-related diseases including gastroesophageal reflux disease and secondary prevention of aspirin/NSAID-induced ulcers. Although clinically... -
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- Evaluations of Gastric Acid Pocket Using Novel Vertical 8-Channel pH Monitoring System and Effects of Acid Secretion Inhibitors
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Sumi S, Ishimura N, Mikami H, Okimoto E, Tamagawa Y, Mishiro T, Kinoshita Y, Ishihara S
- KMID: 2517531
- J Neurogastroenterol Motil.
- 2021 Jul;27(3):370-376.
- doi: 10.5056/jnm20115
Background/Aims The gastric acid pocket has an important role in gastroesophageal reflux disease development. In this study, we utilized a novel 8-channel pH monitoring system with sensor intervals of 1 cm... -
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- Acotiamide Has No Effects on Esophageal Motor Activity or Esophagogastric Junction Compliance
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Mikami H, Ishimura N, Okada M, Izumi D, Okimoto E, Ishihara S, Kinoshita
- KMID: 2413100
- J Neurogastroenterol Motil.
- 2018 Apr;24(2):241-247.
- doi: 10.5056/jnm16111
BACKGROUND/AIMS: The novel prokinetic drug acotiamide is used for treatment of functional dyspepsia. It is still unclear how acotiamide has effects on esophageal motor function. Esophageal peristalsis and esophagogastric junction... -
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- Perianal and Vulvar Extramammary Paget Disease: A Report of Six Cases and Mapping Biopsy of the Anal Canal
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Nagai Y, Kazama S, Yamada D, Miyagawa T, Murono K, Yasuda K, Nishikawa , Tanaka T, Kiyomatsu , Hata K, Kawai K, Masui Y, Nozawa H, Yamaguchi , Ishihara S, Kadono T, Watanabe T
- KMID: 2382888
- Ann Dermatol.
- 2016 Oct;28(5):624-628.
- doi: 10.5021/ad.2016.28.5.624
Treatment of perianal and vulvar extramammary Paget disease (EMPD), rare intraepithelial malignancies, is often challenging because of its potential to spread into the anal canal. However, there is still no... -
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- Effects of Metoclopramide on Esophageal Motor Activity and Esophagogastric Junction Compliance in Healthy Volunteers
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Mikami H, Ishimura N, Fukazawa K, Okada M, Izumi D, Shimura S, Okimoto E, Aimi M, Ishihara S, Kinoshita
- KMID: 2379710
- J Neurogastroenterol Motil.
- 2016 Jan;22(1):112-117.
- doi: 10.5056/jnm15130
BACKGROUND/AIMS: Prokinetic drugs such as metoclopramide are frequently used as second-line therapy for patients with gastroesophageal reflux disease. However, their beneficial effects remain unclear. Esophageal motor activities and compliance of... -
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- Distinction between Chronic Enteropathy Associated with the SLCO2A1 Gene and Crohn's Disease
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Yanai S, Yamaguchi , Nakamura S, Kawasaki K, Toya Y, Yamada N, Eizuka M, Uesugi N, Umeno J, Esaki M, Okimoto E, Ishihara S, Sugai T, Matsumoto
- KMID: 2434392
- Gut Liver.
- 2019 Jan;13(1):62-66.
- doi: 10.5009/gnl18261
BACKGROUND/AIMS: We recently identified recessive mutations in the solute carrier organic anion transporter family member 2A1 gene (SLCO2A1) as causative variants of chronic nonspecific multiple ulcers of the small intestine... -
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- Small Intestinal Bacterial Overgrowth in Patients with Refractory Functional Gastrointestinal Disorders
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Shimura S, Ishimura N, Mikami H, Okimoto E, Uno G, Tamagawa Y, Aimi M, Oshima N, Sato S, Ishihara S, Kinoshita
- KMID: 2379704
- J Neurogastroenterol Motil.
- 2016 Jan;22(1):60-68.
- doi: 10.5056/jnm15116
BACKGROUND/AIMS: Small intestinal bacterial overgrowth (SIBO) is considered to be involved in the pathogenesis of functional gastrointestinal disorders (FGID). However, the prevalence and clinical conditions of SIBO in patients with... -
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- Tissue factor expression is associated with recurrence in patients with non-metastatic colorectal cancer
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Jung HJ, Kim HJ, Kaneko K, Kazama Y, Kawai K, Ishihara S, Choi GS
- KMID: 2432611
- Korean J Clin Oncol.
- 2018 Dec;14(2):128-134.
- doi: 10.14216/kjco.18022
PURPOSE: Previous studies have addressed the role of the hypercoagulable state in the pathogenesis of cancer progression and metastasis. In this study, we investigated the association between coagulation factors, including... -
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- Metabolic Syndrome is a Predisposing Factor for Diffuse Idiopathic Skeletal Hyperostosis
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Okada E, Ishihara S, Azuma K, Michikawa T, Suzuki S, Tsuji O, Nori S, Nagoshi N, Yagi M, Takayama M, Tsuji T, Fujita N, Nakamura M, Matsumoto M, Watanabe K
- KMID: 2514293
- Neurospine.
- 2021 Mar;18(1):109-116.
- doi: 10.14245/ns.2040350.175
Objective: Diffuse idiopathic skeletal hyperostosis (DISH) causes spinal ankylosis, which can result in patients suffering specific spinal fractures that lead to a reduction in the activities of daily life in... -
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