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Tips for Preservation of Parathyroid Gland During Thyroid Surgery

Kim JH

Failure to preserve parathyroid function in patients who have undergone total thyroidectomy is of major concern because hypocalcemia is difficult to prevent and remains a common postoperative complication. It is...
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Completion Thyroidectomy

Cheon Y, Shin SC, Lee BJ

Completion thyroidectomy is defined as surgical removal of the remnant thyroid tissue after resection of the thyroid gland. The frequency of completion thyroidectomy varies among researchers, but is estimated to...
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Persistent Hypokalemic Paralysis in a Patient with Graves’ Disease and Gitelman Syndrome

Jeong JW, Yu TY

Thyrotoxic periodic paralysis (TPP) is a potentially life-threatening condition. Graves’ disease accounts for the majority of cases of TPP. However, another diagnosis should be considered when repeated hypokalemic paralysis occurs...
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Current Status and Future Perspective of the Treatment for Radioiodine Refractory Differentiated Thyroid Cancer

Shong YK

Radioiodine refractory differentiated thyroid cancers are rare but they make a definite problem since they run relentlessly progressive course leading to death in a few years. Recent development of various...
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Neck Discomfort after Thyroidectomy

Kim B, Park JH

Thyroid and parathyroid surgery is commonly performed for diagnostic or therapeutic purposes for benign tumors as well as malignant tumors. Vocal cord paralysis and hypoparathyroidism are known as major complications....
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Thyroid and Gut Microbiome

Kwon SK, Kim N, Park YJ

The gut microbiome affects the enterohepatic recycling of thyroid hormone and the metabolism and absorption of micronutrients including iodine and selenium. Changes in thyroid function trigger changes in the neuro-muscular...
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Thyroid Lobectomy as an Initial Treatment Option on 1-4 cm Papillary Cancer

Cho JS

Recently, the early diagnosis and treatment of differentiated thyroid cancer has significantly increased the proportion of thyroid lobectomy rather than total thyroidectomy. Thyroid lobectomy is recommended for less than 1...
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Optimal Surgical Extent of Therapeutic Lateral Neck Dissection in Well-Differentiated Thyroid Carcinoma Patients with Clinical Lateral Lymph Node Metastasis

Won HR, Koo BS

Regional neck metastases in well-differentiated thyroid carcinoma (WDTC) are relatively frequent. The prognostic effects of lymph node (LN) metastases remain controversial. However, it is well known that lateral LN metastasis...
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Subacute Thyroiditis Developed While Waiting for Papillary Thyroid Cancer Surgery: Pathologically Proven Two Cases

Kim DH, Hong CM, Han MH, Lee J

Co-existence of subacute thyroiditis and papillary thyroid cancer (PTC) is rarely reported. We have recently experienced interesting cases of subacute thyroiditis, which developed while waiting for elective surgery of thyroid...
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Serum Carcinoembryonic Antigen as a Biomarker for Medullary Thyroid Cancer

Kim J, Park H, Choi MS, Park J, Jang HW, Kim TH, Kim SW, Chung JH

Background and Objectives: The lack of known elevated biomarkers in cancer surveillance is a challenge for diagnostics. However, few studies have assessed the proportion of patients with medullary thyroid cancer...
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A Newly Developed Pancreatic Adenocarcinoma in a Patient with Advanced Thyroid Cancer under Long-Term Sorafenib Use

Kim MJ, Baek HS, Lee SH, Lim DJ

Sorafenib, an oral multi-target tyrosine kinase inhibitor (MTKI) for treatment of radioiodine-refractory differentiated thyroid cancer can induce acute or chronic pancreatitis as an adverse event. However, there have been no...
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Treatment Effect of Combining Lenvatinib and Vemurafenib for BRAF Mutated Anaplastic Thyroid Cancer

Hong CM, Oh JM, Gangadaran P, Rajendran RL, Ahn BC

Background and Objectives: Even though most of the thyroid cancer shows good prognosis, de-differentiated thyroid cancer is still refractory to conventional treatments. Recently, kinase inhibitors including multi-kinase and BRAF inhibitors...
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Null Association between BRAF V600E Mutation and Tumor Recurrence in Patients with Papillary Thyroid Microcarcinoma in South Korea

Kim JY, Kim KJ, Bae JH, Kim JH, Kim NH, Kim HY, Kim HY, Baek SK, Kim SG, Jung KY, Kim KJ

Background and Objectives: The clinical implications of the BRAF V600E mutation in papillary thyroid microcarcinoma (PTMC), defined as ≤1.0 cm of tumor size, remain controversial. We investigated the association between...
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Cooperative Subtype Switch of Thyroid Hormone Receptor and Nuclear Receptor Corepressor Related Epithelial–Mesenchymal Transition in Papillary Thyroid Cancer

Jeong S, Lee SG, Kim H, Lee G, Park S, Kim IK, Lee J, Jo YS

Background and Objectives: Although thyroid hormones affect human cancer progression, the regulatory mechanism of thyroid hormone receptors in carcinogenesis has not been elucidated. This study aimed to evaluate the expression...
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