- Modulation of Osteogenic Differentiation of Adipose-Derived Stromal Cells by Co-Treatment with 3, 4’-Dihydroxyflavone, U0126, and N-Acetyl Cysteine
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Song K, Yang GM, Han J, Gil M, Dayem AA, Kim K, Lim KM, Kang GH, Kim S, Jang SB, Vellingiri B, Cho SG
- KMID: 2532407
- Int J Stem Cells.
- 2022 Aug;15(3):334-345.
- doi: 10.15283/ijsc22044
Background and Objectives: Flavonoids form the largest group of plant phenols and have various biological and pharma-cological activities. In this study, we investigated the effect of a flavonoid, 3, 4’-dihydroxyflavone... -
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- Immunomodulatory Effect of Epidermal Growth Factor Secreted by Human Umbilical Cord Blood-Derived Mesenchymal Stem Cells on Atopic Dermatitis
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Jung N, Kong T, Yu Y, Park H, Lee E, Yoo S, Baek S, Lee S, Kang KS
- KMID: 2532405
- Int J Stem Cells.
- 2022 Aug;15(3):311-323.
- doi: 10.15283/ijsc21173
Background and Objectives: Human mesenchymal stem cells (MSCs) are emerging as a treatment for atopic dermatitis (AD), a chronic inflammatory skin disorder that affects a large number of people across... -
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- YBX1 Promotes the Inclusion of RUNX2 Alternative Exon 5 in Dental Pulp Stem Cells
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Shen J, She W, Zhang F, Guo J, Jia R
- KMID: 2532404
- Int J Stem Cells.
- 2022 Aug;15(3):301-310.
- doi: 10.15283/ijsc21035
Background and Objectives: RUNX2 plays an essential role during the odontoblast differentiation of dental pulp stem cells (DPSCs). RUNX2 Exon 5 is an alternative exon and essential for RUNX2 transcriptional... -
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- The Biphasic Effect of Retinoic Acid Signaling Pathway on the Biased Differentiation of Atrial-like and Sinoatrial Node-like Cells from hiPSC
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Liu F, Long D, Huang W, Peng W, Lan H, Zhou Y, Dang X, Zhou R
- KMID: 2532399
- Int J Stem Cells.
- 2022 Aug;15(3):247-257.
- doi: 10.15283/ijsc21148
Background and Objectives: Although human-induced pluripotent stem cells (hiPSC) can be efficiently differentiated into cardiomyocytes (CMs), the heterogeneity of the hiPSC-CMs hampers their applications in research and regenerative medicine. Retinoic... -
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- Lupus Heart Disease Modeling with Combination of Induced Pluripotent Stem Cell-Derived Cardiomyocytes and Lupus Patient Serum
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Park N, Rim YA, Jung H, Nam Y, Ju JH
- KMID: 2532398
- Int J Stem Cells.
- 2022 Aug;15(3):233-246.
- doi: 10.15283/ijsc21158
Background and Objectives: Systemic lupus erythematosus (SLE) is a chronic autoimmune disease mainly affecting young women of childbearing age. SLE affects the skin, joints, muscles, kidneys, lungs, and heart. Cardiovascular... -
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- Abnormal Development of Neural Stem Cell Niche in the Dentate Gyrus of Menkes Disease
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Cho Sk, Gwon S, Kim HA, Kim J, Cho SY, Kim DE, Chae JH, Park DH, Hwang YK
- KMID: 2532401
- Int J Stem Cells.
- 2022 Aug;15(3):270-282.
- doi: 10.15283/ijsc21088
Background and Objectives: Menkes disease (MNK) is a rare X-linked recessive disease, caused by mutations in the copper transporting ATP7A gene that is required for copper homeostasis. MNK patients experience... -
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- Development of a High-Yield Isolation Protocol Optimized for the Retrieval of Active Muscle Satellite Cells from Mouse Skeletal Muscle Tissue
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Lee H, Han NR, Kim SJ, Yun JI, Lee ST
- KMID: 2532403
- Int J Stem Cells.
- 2022 Aug;15(3):283-290.
- doi: 10.15283/ijsc21179
Background and Objectives: Difficulties often encountered in separating and purifying active muscle satellite cells (MSCs) from skeletal muscle tissues have limited the supply of cells for muscle therapy and artificial... -
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- MiR-29a-3p Inhibits Proliferation and Osteogenic Differentiation of Human Bone Marrow Mesenchymal Stem Cells via Targeting FOXO3 and Repressing Wnt/β-Catenin Signaling in Steroid-Associated Osteonecrosis
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Wang C, Zhu M, Yang D, Hu X, Wen X, Liu A
- KMID: 2532406
- Int J Stem Cells.
- 2022 Aug;15(3):324-333.
- doi: 10.15283/ijsc21147
Background and Objectives: This study was to investigate the role of microRNA-29a-3p (miR-29a-3p) in human bone marrow mesenchymal stem cells (hBMSCs), and its relationship with steroid-associated osteonecrosis. Methods and Results: The... -
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- Xenogeneic Humoral Immune Responses to Human Mesenchymal Stem Cells in Mice
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Hong JM, Kim JH, Kim GH, Shin HM, Hwang Yi
- KMID: 2532402
- Int J Stem Cells.
- 2022 Aug;15(3):291-300.
- doi: 10.15283/ijsc21116
Background and Objectives: Many preclinical studies have been conducted using animal disease models to determine the effectiveness of human mesenchymal stem cells (hMSCs) for treating immune and inflammatory diseases based... -
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- Establishment of Neurotoxicity Assessment Using Microelectrode Array (MEA) with hiPSC-Derived Neurons and Evaluation of New Psychoactive Substances (NPS)
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Kang Kr, Kim CY, Kim J, Ryu B, Lee SG, Baek J, Kim YJ, Lee JM, Lee Y, Choi SO, Woo DH, Park IH, Chung HM
- KMID: 2532400
- Int J Stem Cells.
- 2022 Aug;15(3):258-269.
- doi: 10.15283/ijsc21217
Background and Objectives: Currently, safety pharmacological tests for the central nervous system depend on animal behavioral analysis. However, due to the subjectivity of behavioral analysis and differences between species, there... -
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