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The Role of Cytokines in Allergy

Lee CH

  • KMID: 2131694
  • J Rhinol.
  • 1998 May;5(1):5-10.
Several pathophysiologic features of allergic inflammation, such as T(H) differentiation, the regulation of IgE, eosinophilia, mast cell proliferation, and cellular recruitment, are regulated by various cytokines. It has been of...
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Parasite Infections and Allergy

Yong TS

There has been a negative association between certain parasite infections at an early age and allergic diseases based on the epidemiological data. Parasitic helminths excrete or secrete products/allergens which develop...
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Effects of Interleukin-9 Blockade on Chronic Airway Inflammation in Murine Asthma Models

Kim MS, Cho KA, Cho YJ, Woo SY

PURPOSE: Asthma is a chronic inflammatory disease of the airways associated with structural changes and airway remodeling. Interleukin (IL)-9 has pleiotropic effects on both inflammatory cells and airway structural cells,...
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Identification of UVB Effects on Gene Expressed by Normal Human Melanocytes

Kim HS, Park HH, Lee MH

  • KMID: 1977852
  • Korean J Dermatol.
  • 2003 Dec;41(12):1597-1602.
BACKGROUND: Irradiation of the skin with ultraviolet rays result in alterations of immune response as well as melanogenesis and melanocarcinogenensis. These effects are largely mediated by soluble mediators released from...
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Ectopically Expressed Membrane-bound Form of IL-9 Exerts Immune-stimulatory Effect on CT26 Colon Carcinoma Cells

Do Thi VA, Park SM, Lee H, Kim YS

IL-9 is a known T cell growth factor with pleiotropic immunological functions, especially in parasite infection and colitis. However, its role in tumor growth is controversial. In this study, we...
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Effect of Interleukin-9 on Cell Proliferation and Histamine Release of Cord Blood-derived Human Mast Cells

Ahn KM, Lee KS, Shin MY, Park HY, Ahn YH, Son DY, Lee SI

  • KMID: 2051388
  • Pediatr Allergy Respir Dis.
  • 2002 Dec;12(4):282-290.
PURPOSE: Interleukin-9(IL-9), one of Th2-type cytokines, might be important in the pathophysiology of allergic diseases. We investigated the effect of IL-9 on human mast cells by assessing cell proliferation and...
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Anti-Interleukin-9 Antibody Increases the Effect of Allergen-Specific Immunotherapy in Murine Allergic Rhinitis

Shin JH, Kim DH, Kim BY, Kim SW, Hwang SH, Lee J, Kim SW

PURPOSE: Interleukin (IL)-9 induces allergic responses; however, the roles of anti-IL-9 antibody in the induction of tolerance remain unclear. This study investigated the effects of anti-IL-9 antibody on oral tolerance...
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Innate lymphoid cells and cytokines of the novel subtypes of helper T cells in asthma

Sherkat R, Yazdani R, Ganjalikhani Hakemi M, Homayouni , Farahani R, Hosseini M, Rezaei A

BACKGROUND: In this study, the expression of interleukin-9 (IL-9), IL-17, IL-22, and IL-25 genes that might be the potential predisposing factors for asthma as well as count of innate lymphoid...
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Regulation of IgE-Mediated Food Allergy by IL-9 Producing Mucosal Mast Cells and Type 2 Innate Lymphoid Cells

Lee JB

Due to the increasing prevalence and number of life-threatening cases, food allergy has emerged as a major health concern. The classic immune response seen during food allergy is allergen-specific IgE...
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In-Depth, Proteomic Analysis of Nasal Secretions from Patients With Chronic Rhinosinusitis and Nasal Polyps

Kim YS, Han D, Kim J, Kim DW, Kim YM, Mo JH, Choi HG, Park JW, Shin HW

PURPOSE: Chronic rhinosinusitis (CRS) is a complex immunological condition, and novel experimental modalities are required to explore various clinical and pathophysiological endotypes; mere evaluation of nasal polyp (NP) status is...
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Differences in Genetic Variations Between Treatable and Recalcitrant Atopic Dermatitis in Korean

Jun M, Wang HY, Lee S, Choi E, Lee H, Choi EH

PURPOSE: Variations in barrier- or immune response-related genes are closely related to the development of atopic dermatitis (AD). This study was designed to identify genetic variations and clinical features to...
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