- The Role of Cytokines in Allergy
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Lee CH
- KMID: 2131694
- J Rhinol.
- 1998 May;5(1):5-10.
Several pathophysiologic features of allergic inflammation, such as T(H) differentiation, the regulation of IgE, eosinophilia, mast cell proliferation, and cellular recruitment, are regulated by various cytokines. It has been of... -
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- Role of IL-23 and Th17 Cells in Airway Inflammation in Asthma
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Nakajima H, Hirose K
- KMID: 1456191
- Immune Netw.
- 2010 Feb;10(1):1-4.
- doi: 10.4110/in.2010.10.1.1
Asthma is characterized by chronic airway inflammation with intense eosinophil and lymphocyte infiltration, mucus hyperproduction, and airway hyperresponsiveness. Accumulating evidence indicates that antigen-specific Th2 cells and their cytokines such as... -
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- The Role of Type 2 Innate Lymphoid Cells in Allergic Diseases
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- KMID: 2299449
- Korean J Asthma Allergy Clin Immunol.
- 2012 Dec;32(4):207-212.
Innate lymphoid cells have recently been identified to be a cell population that has morphology typical of lymphocytes but lacks rearranged antigen receptors. It can be classified into RORgammat innate... -
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- mRNA Expression of Cytokines and Release of Metalloproteinases around Loose Cemented Total Hip Arthroplasty
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Kim SY, Kyung HS, Shin HI, Choi JY, Kim MK, Kim JC
- KMID: 2105448
- J Korean Orthop Assoc.
- 1998 Nov;33(6):1537-1545.
The aim of the present study was to investigate the mRNA expression of several cytokines which were not reported previously from interface tissues around loose cemented acetabulum to obtain better... -
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- Differential Expressions of IL-3 and FcepsilonRI in the Peripheral Blood Mononuclear Cells and Lesional Skin of Patients with Extrinsic Atopic Dermatitis and Intrinsic Atopic Dermatitis
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Jin S, Noh S, Bae BG, Park CO, Lee KH
- KMID: 1451617
- Korean J Dermatol.
- 2011 Jun;49(6):491-498.
BACKGROUND: A small subgroup of atopic dermatitis (AD) patients show low total and allergen-specific immunoglobulin (IgE) levels. This subgroup has been termed 'intrinsic' AD (IAD) as compared to its counterpart... -
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- Differential diagnosis of ovarian cancer and benign ovarian diseases using cytokine levels in the peritoneal fluids
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Yang SM, Song KE, Suh JS, Cho YL
- KMID: 2225973
- Korean J Clin Pathol.
- 2000 Dec;20(6):527-533.
BACKGROUND: Cytokines play a key role in the regulation of cells of the immune system and also have been implicated in the pathogenesis of malignant disease. Usually malignant cells secreted... -
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- A Study of the Expression of Cytokines and p53 in Nasal Polyps
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Ju MS, Kim CN, Hong YS
- KMID: 2131739
- J Rhinol.
- 1999 Nov;6(2):91-98.
BACKGROUND AND OBJECTIVES: Nasal polyps are a condition of uncertain etiology. Cytokines are thought to play a role in nasal polyps in vitro, but in vivo studies on the patterns... -
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- Activity of Cytokines and Expression of CD62L in Patients with Bronchial Asthma
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Song KS, Lee WY, Hong AR, Kim HS, Yong SJ, Shin KC
- KMID: 2114498
- Tuberc Respir Dis.
- 1998 Feb;45(1):90-98.
- doi: 10.4046/trd.1998.45.1.90
BACKGROUND: The CD4+ T-helper cells comprise functionally distinct subsets of Th1 and Th2 cells that are distinguished on the basis of differential cytokines production. Th1 cells secrete interferon-gamma, lymphotoxin, interleukin-2.... -
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- Sinensetin Inhibits Interleukin-6 in Human Mast Cell - 1 Via Signal Transducers and Activators of the Transcription 3 (STAT3) and Nuclear Factor Kappa B (NF-κB) Pathways
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Chae HS, Kim YM, Chin YW
- KMID: 2376491
- Nat Prod Sci.
- 2017 Mar;23(1):1-4.
- doi: 10.20307/nps.2017.23.1.1
Sinensetin, a pentamethoxyflavone, is known to exert various pharmacological activities including anti-angiogenesis, anti-diabetic and anti-inflammatory activities. However, its effects on the human mast cell - 1 (HMC-1) mediated inflammatory mechanism... -
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- Production of Interleukin-5, Interleukin-13 and Interferon-gamma in Peripheral Blood CD8+T Cells from Children with Wheezing
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Lee MH, Moon S, Jang JH, Chung MS, Kim E, Yoon JS, Kim HH, Lee JS
- KMID: 2314888
- Pediatr Allergy Respir Dis.
- 2008 Sep;18(3):228-235.
PURPOSE: Our objective was to investigate the role of CD8+T cells in pathogenesis of wheezing in children with atopic nature. METHODS: Twelve atopic wheezers, 8 nonatopic wheezers, 8 disease controls and... -
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- Eosinophil Cationic Protein in HSP and in IgA Nephropathy
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Namgoong M, Kim JS
- KMID: 2254997
- Korean J Nephrol.
- 1997 Mar;16(1):21-27.
Interleukin-5 (IL-5), which is known to be an activator of human eosinophil, increases in IgA nephropathy. In order to find out the relationship between activated eosinophil function and the pathogenesis... -
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- Effect of interleukin-12 on airway inflammation in mouse model of bronchial asthma
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Lee SY, Song JS
- KMID: 2286080
- J Asthma Allergy Clin Immunol.
- 1999 Feb;19(1):79-90.
BACKGROUND: Th2-like cells are thought to play a crucial role in the recruitment and activation of eosinophil in bronchial asthma. In contrast to Th2 cytokine, Thl cytokine IFN-y decreases eosinophil recruitment. Previous... -
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- Characterization of Th2 Cytokines, IL-5, IL-10 and IL-13, in Otitis Media with Effusion: Comparison of Allergy and Non Allergy
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Jung MK, Lee CH, Kim SW, Chang KH, Yeo SW
- KMID: 2276009
- Korean J Otolaryngol-Head Neck Surg.
- 2003 Jun;46(6):459-463.
BACKGROUND AND OBJECTIVES: While it has been reasonably well demonstrated that allergy is a risk factor for patients of otitis media with effusion (OME), the causal mechanism is not well... -
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- Effects of VitabridC¹² on Skin Inflammation
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Lee JH, Jeon YJ, Choi JH, Kim HY, Kim TY
- KMID: 2388905
- Ann Dermatol.
- 2017 Oct;29(5):548-558.
- doi: 10.5021/ad.2017.29.5.548
BACKGROUND: VitabridC¹² is newly developed and composed of vitamin C and Vitabrid (lamellar, hydrated zinc oxide). OBJECTIVE: In this study, we aimed to investigate the effects of VitabridC¹² on psoriasis and... -
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- Identification of cytokines inhibiting eosinophil activation and the inhibitory mechanism
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Park CS, Choi EN, Lee YM, Park SW, Jang AS, Lee JH, Choi YS, Chung IY
- KMID: 2178415
- J Asthma Allergy Clin Immunol.
- 2003 Dec;23(4):759-772.
No abstract available. -
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- Emerging Endotypes of Chronic Rhinosinusitis and Its Application to Precision Medicine
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Kim DW, Cho SH
- KMID: 2378192
- Allergy Asthma Immunol Res.
- 2017 Jul;9(4):299-306.
- doi: 10.4168/aair.2017.9.4.299
Chronic rhinosinusitis (CRS) is a heterogeneous inflammatory disease with various underlying pathophysiologic mechanisms which translate to endotypes, in contrast to clinical phenotypes or histological subtypes. Defining endotypes can help clinicians... -
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- Comparison of cytokine expression profiles in infants with a rhinovirus induced lower respiratory tract infection with or without wheezing: a comparison with respiratory syncytial virus
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Roh DE, Park SH, Choi HJ, Kim YH
- KMID: 2390498
- Korean J Pediatr.
- 2017 Sep;60(9):296-301.
- doi: 10.3345/kjp.2017.60.9.296
PURPOSE: The aim of this study was to evaluate whether infants with rhinovirus (RV) infection-induced wheezing and those with respiratory syncytial virus (RSV) infection-induced wheezing have different cytokine profiles in... -
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- The relationship between eosinophilia and serum cytokine concentrations in maintenance hemodialysis patients
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Park EM, Kim H, Jung SS, Yun JW, Koo ES, Lee KB, Keum DK
- KMID: 2252797
- Korean J Med.
- 2003 May;64(5):561-566.
BACKGROUND: Eosinophilia in hemodialysis (HD) patients has been associated with allergic reactions to dialyzers and exaggerated activation of complement during HD. Complement activation can lead to cytokine production. The... -
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- The Effect of Interleukin-12 on the Immune Response in Allergic Rhinitis Mouse Model
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Kang SM, Ryu HY, Lee JH
- KMID: 2314241
- Pediatr Allergy Respir Dis.
- 2001 Sep;11(3):213-223.
PURPOSE: Interleukin-12, produced by tissue macrophages and B lymphocytes, stimulates proliferation of Th1-type cells, while inhibiting the generation of Th2- type cytokines and IgE production. The mice were sensitized and... -
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- The Effect of Bacterial Lipopolysaccharide on the Lymphokine Production of the T Lymphocytes
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Moon HB, Yun KJ, Han WC, Lim CW, Kwon HN, Park YS
- KMID: 1725230
- Korean J Pathol.
- 1997 Mar;31(3):244-251.
It is well known that the murine T helper cell clones are divided by their lymphokine secretory activities. One is the Th-1 cell, producing IL-2 and IFN after... -
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