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Calcium/Calmodulin-Dependent Protein Kinase is Involved in the Release of High Mobility Group Box 1 Via the Interferon-beta Signaling Pathway

Ma L, Kim SJ, Oh KI

  • KMID: 2424209
  • Immune Netw.
  • 2012 Aug;12(4):148-154.
Previously, we have reported that high mobility group box 1 (HMGB1), a proinflammatory mediator in sepsis, is released via the IFN-beta-mediated JAK/STAT pathway. However, detailed mechanisms are still unclear. In...
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Genetic characterization of bovine viral diarrhea virus strains in Beijing, China and innate immune responses of peripheral blood mononuclear cells in persistently infected dairy cattle

Weng XG, Song QJ, Wu Q, Liu MC, Wang ML, Wang JF

To acquire epidemiological data on the bovine viral diarrhea virus (BVDV) and identify cattle persistently infected (PI) with this virus, 4,327 samples from Holstein dairy cows were screened over a...
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Ribosomal Protein L19 and L22 Modulate TLR3 Signaling

Yang EJ, Seo JW, Choi IH

BACKGROUND: Toll-like receptor 3 (TLR3) recognizes double-stranded RNA (dsRNA) and induces inflammation. In this study we attempted to ascertain if there are endogenous host molecules controlling the production of cytokines...
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Interferon-Stimulated Genes Response in Endothelial Cells Following Hantaan Virus Infection

Kim IW, Hwang JY, Kim SK, Kim JK, Park HS

The regulation mechanism of interferon (IFN) and IFN-stimulated genes is a very complex procedure and is dependent on cell types and virus species. We observed molecular changes related to anti-viral...
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