- Adenosine Deaminase in Human Skin
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Kim YP, Kahng JB, Chon JY, Ihm CW
- KMID: 1678269
- Korean J Dermatol.
- 1981 Aug;19(4):385-389.
Adenosine deaminase (adenosine aminohydrolase, AL)A), which catalyzes the deamination of adenosine to yield inosine and amrnonia, was assayed in human penile foreskin. The skin tissue was separated into two layers;... -
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- Further Studies of Adenosine Deaminase in the Human Skin (II)
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Ihm CW, Kim YP, Choi YS
- KMID: 1678650
- Korean J Dermatol.
- 1983 Feb;21(1):71-75.
Adenosine deaminase (adenosine aminohydrolase, E.C.3. 5. 4. 4; ADA), which catalyzes the deamination of adenosine to yield inosine and ammonia, was characterized in the human penile foreskin. ADA was found... -
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- Diagnostic Value of Adenosine Deaminase Activity in Tuberculous Pericardial Effusion
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Park KS, Kim CH, Min BC, Choe KH
- KMID: 2229396
- Korean Circ J.
- 1990 Mar;20(1):141-147.
- doi: 10.4070/kcj.1990.20.1.141
Adenosine deaminase(ADA) is an enzyme capable of catalysing the pathway from adenosine to inosine. Previous studies have shown that this enzyme may be useful in recognition of a tubeculous etiology... -
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- Identification of Diverse Adenosine-to-Inosine RNA Editing Subtypes in Colorectal Cancer
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Lee SH, Kim HP, Kang JK, Song SH, Han SW, Kim TY
- KMID: 2394826
- Cancer Res Treat.
- 2017 Oct;49(4):1077-1087.
- doi: 10.4143/crt.2016.301
PURPOSE: RNA editing generates protein diversity by altering RNA sequences in coding regions without changing the overall DNA sequence. Adenosine-to-inosine (A-to-I) RNA editing events have recently been reported in some... -
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- Effects of Inosine Monophosphate Dehydrogenase Inhibition on Platelet-derived Growth Factor- Induced Fibronectin Secretion and Cellular Reactive Oxygen Species in Mouse Mesangial Cells
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Park J, Song JS, Huh KH, Ju MK, Chang HK, Ahn HJ, Kim MS, Kim YS
- KMID: 2201873
- J Korean Soc Transplant.
- 2007 Dec;21(2):210-215.
PURPOSE: Mesangial cell extracellular matrix (ECM) synthesis plays an important role in various renal diseases. Mycophenolic acid (MPA), which is an inhibitor of inosine monophosphate dehydrogenase (IMPDH), inhibits mesangial cell... -
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- Mycophenolic Acid Induced Apoptosis in Human Jurkat Cells viathe Generation of Reactive Oxygen Species
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Lee DK, Lee HK, Choi SJ, Chung SY
- KMID: 1476276
- J Korean Surg Soc.
- 2008 Sep;75(3):149-155.
PURPOSE: Mycophenolic acid (MPA) is the active agent of mycophenolate mofetil (MMF), which is an immunosuppressive drug. MPA is a selective inhibitor of inosine monophosphate dehydrogenase. The aim of this... -
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- Clinical Utility of Adenosine Deaminase Isoenzyme Determinations in Leukemia
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Shin DH, Cho HC, Kang SH, Park IG, Yoon KJ
- KMID: 2225847
- Korean J Clin Pathol.
- 1999 Apr;19(2):181-189.
BACKGROUND: Adenosine deaminase (ADA), an enzyme involved in purine metabolism, catalyzes the hydrolytic deamination of adenosine or 2-deoxyadenosine to inosine or 2-deoxyinosine. Human ADA consists of three molecular forms: ADA1,... -
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- Analysis of nucleotides and their derivatives in renal tissue of rat during ischemia by HPLC
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Kim SY, Kim JH
- KMID: 2377607
- Yeungnam Univ J Med.
- 1992 Jun;9(1):90-101.
- doi: 10.12701/yujm.1992.9.1.90
In rat kidney, the changes in concentrations of nucleotides and their derivatives during ischemia induced by renal artery ligation was measured quantitatively with high performance liquid chromatography (HPLC). After the ligation... -
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- Clinical Experience of Subacute Sclerosing Panencephalitis treated with Alpha-interferon and Ionsiplex
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Lee SC, Lee SH, Rho SK, Park KH, Kim SW
- KMID: 2342449
- J Korean Neurol Assoc.
- 1994 Sep;12(3):542-551.
Subacute sclerosing panencephalitis (SSPE) is a slowly progressing, chronic persistent fatal central nervous system disease, involving gray and white matter, especially white matter caused by measles virus that affecting children... -
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- Effects of Mycophenolate Mofetil on Acute Rejection of Allografted Kidney
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Kim HT, Cho WH, Park CH, Park SB, Kim HC
- KMID: 2144944
- J Korean Soc Transplant.
- 1998 Nov;12(2):253-260.
Mycophenolate mofetil (MMF) is a novel new immunosuppressant which suppress proliferation of T and B lymphocytes by inhibiting inosine monophosphate dehydrogenase. Even though the results we can get now are... -
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- Purification and Characterization of Guanine Aminohydrolase from Rat Cerebrum
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Cha HJ, Jung HW, Koh YC, Sim BS, Park JB, Kim SW
- KMID: 1953539
- J Korean Neurosurg Soc.
- 1984 Dec;13(4):611-625.
Guanine aminohydrolase(GAH;EC 3. 5. 4. 3.) was partially purified 122-fold from rat cerebrum to a specific activity of 7.22 in its per mg protein with a recovery of 7.47% by... -
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- Mizoribine Inhibits Production of Pro-inflammatory Cytokines and PGE2 in Macrophages
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Han S, Kim K, Kim H, Kwon J, Ha N, Lee CK, Kim K
- KMID: 2150625
- Immune Netw.
- 2007 Mar;7(1):31-38.
- doi: 10.4110/in.2007.7.1.31
BACKGROUND: Mizoribine (MZR) is an imidazole nucleoside isolated from Eupenicillium brefeldianum. MZR is currently in clinical use for patients who have undergone renal transplantation. Therapeutic efficacy of MZR has also... -
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- Mycophenolic Acid Induced Apoptotic Signal Transduction in Molt-4 T-cells
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Choi SJ, Chung SY, Kim SK
- KMID: 2004711
- J Korean Surg Soc.
- 2002 Jan;62(1):8-17.
PURPOSE: Mycophenolic acid (MPA), a selective inhibitor of inosine monophosphate dehydrogenase (IMPDH), is the active metabolite of the immunosuppressive drug, mycophenolate mofetil (MMF). MMF is used to prevent an immune-... -
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- In Vitro Perfusion Studies on Coronary Function of Cardiac Ischemia-Reperfusion in Spontaneously Hypertensive Rat Heart
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Kim EJ, Kang YH
- KMID: 2228957
- Korean Circ J.
- 1995 Feb;25(1):59-67.
- doi: 10.4070/kcj.1995.25.1.59
BACKGROUND: Myocardial ischemia in human hypertension and in various animal models of hypertension may be due to abnormal maximal coronary vasodilator reserve and disturbaces of coronary vasomotion. The vascular reactivity... -
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- Mizoribine-mediated Apoptosis Signaling in Jurkat T Cells
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Seo KW, Chung SH, Chung SY, Kim SK, Choi SN
- KMID: 1896293
- J Korean Surg Soc.
- 2004 Apr;66(4):259-270.
PURPOSE: Mizoribine (MZR), an inhibitor of Inosine monophosphate (IMP) dehydrogenase which depletes cellular GTP, is clinically used as an immunosuppressive drug. This study was designed to evaluate the mechanism by... -
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- Decision Factors on Mycophenolic Acid Dose after Renal Transplantation
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Kim SJ, Kim MS, Han DJ, Yang CW, Lee S, Yun IJ, Cho BS, Lee TW, Rim H, Kim MJ, Han DC, Shin GT, Oh CK, Do JY, Han SY, Choi SJ, Na KR
- KMID: 2097080
- J Korean Soc Transplant.
- 2009 Sep;23(2):135-140.
- doi: 10.4285/jkstn.2009.23.2.135
BACKGROUND: Triple immunosuppressant therapy including anti-metabolites is the representative immunosuppressive therapy after renal transplantation. This study is to evaluate the factors that influence Mycophenolate sodium (MPS, Myfortic, Novartis, Basel, Switzerland)... -
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- Changes in Serum Adenosine Deaminase Activity during Normal Pregnancy
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Lee SJ, Hwang HS, Kim BN, Kim MA, Lee JW, Park YW, Kim YH
- KMID: 1127093
- J Korean Med Sci.
- 2007 Aug;22(4):718-721.
- doi: 10.3346/jkms.2007.22.4.718
Adenosine deaminase (ADA), an enzyme essential for the differentiation of lymphoid cells, has been used for monitoring diseases with altered immunity. The purpose of this study was to investigate the... -
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