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Effect of Hyperglycemia on Myocardial Perfusion in Diabetic Porcine Models and Humans

Park JJ, Kim SH, Kim MA, Chae IH, Choi DJ, Yoon CH

BACKGROUND: Diabetes mellitus (DM) causes macro- and microvasculopathy, but data on cardiac microvascular changes in large animals are scarce. We sought to determine the effect of DM on macro- and...
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Management of Hyperglycemia in Type 2 Diabetes: A Summary of New Consensus Report from the American Diabetes Association and the European Association for the Study of Diabetes in 2018

Kim JM, Kim SS

In 2018, the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD) published a consensus recommendation on management of hyperglycemia. This consensus report emphasized the...
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Hyperglycemia in pediatric age: could it be maturity onset diabetes of the young? Case reports and review of the literature

Cascais M, Pereira E, Vieira A, Venâncio , Ramos L, Moleiro P

Maturity Onset Diabetes of the Young (MODY) includes a clinically and genetically heterogeneous group of diabetes subtypes with MODY-2 being the second most prevalent form. We report 2 cases of...
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The Clinical Presentations and Prognosis of Non-Ketotic Hyperglycemia Induced Seizure

Lee MK, Kim JE, Jang W, Jo KD, Kim WJ, Song JS

BACKGROUND: Seizure can be triggered by the non-ketotic hyperglycemia (NKH). Recently we analysed 18 cases of NKH induced seizure to identify the causes for NKH, seizure types, prognosis, and the...
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Comparison of sevoflurane and propofol anesthesia on the incidence of hyperglycemia in patients with type 2 diabetes undergoing lung surgery

Kim H, Han J, Jung SM, Park SJ, Kwon NK

BACKGROUND: The type and regimen of anesthesia may affect perioperative hyperglycemia following major surgical stress. This study compared the effects of sevoflurane and propofol on the incidence of hyperglycemia and...
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Low Handgrip Strength Is Not Associated with Type 2 Diabetes Mellitus and Hyperglycemia: a Population-Based Study

Giglio BM, Mota JF, Wall BT, Pimentel G

Type 2 diabetes mellitus (DM) is commonly linked to muscle weakness and metabolic abnormalities which increase healthcare costs. The study was undertaken to investigate if low handgrip strength, as a...
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Hyperglycemia aggravates decrease in alpha-synuclein expression in a middle cerebral artery occlusion model

Kang JB, Kim DK, Park DJ, Shah MA, Kim MO, Jung EJ, Lee HS, Koh PO

Hyperglycemia is one of the major risk factors for stroke. Hyperglycemia can lead to a more extensive infarct volume, aggravate neuronal damage after cerebral ischemia. α-Synuclein is especially abundant in...
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A Journey to Understand Glucose Homeostasis: Starting from Rat Glucose Transporter Type 2 Promoter Cloning to Hyperglycemia

Ahn YH

My professional journey to understand the glucose homeostasis began in the 1990s, starting from cloning of the promoter region of glucose transporter type 2 (GLUT2) gene that led us to...
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Coating rice with mulberry leaves rich in deoxynojirimycin ameliorates hyperglycemia and dyslipidemia in C57BL/KsJ db/db mice

Lee J, Lee HJ, Lee JJ

BACKGROUND/OBJECTIVES: Mulberry leaf (ML) has been shown to have an inhibitory effect on α-glucosidase, and suppresses postprandial hyperglycemia, which may be related to its deoxynojirimycin (DNJ) content. This study was...
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The importance of treating mild hyperglycemia in pregnant women with diabetes

Kim KS

No abstract available.
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Hyperglycemia exacerbates downregulation of dynamin-like protein 1 in ischemic cerebral injury

Park DJ, Kim MO, Koh PO

Ischemic stroke is one of the leading causes of adult disability and death. Hyperglycemia is associated with an increased risk of stroke and poor outcomes after brain injury. Dynamin-like protein...
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Icodextrin and spurious hyperglycemia in peritoneal dialysis patients: a hospital-wide attempt to prevent such errors

Asakura Y, Kimura K

No abstract available.
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Effects of Homocysteine and Hyperglycemia on the Proliferation of Aortic Vascular Smooth Muscle Cells of Obese Type 2 Diabetes Rat

Yoo HJ, Yu SH, Cho YJ, Nam HW, Kang DH

BACKGROUND: The aim of this study was to investigate the role of homocysteine on the proliferation of rat aortic vascular smooth muscle cells (VSMCs) by measuring mitogen-activated protein (MAP) kinase...
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Hyperglycemia decreases preoxiredoxin-2 expression in a middle cerebral artery occlusion model

Koh PO

Diabetes is a major risk factor for stroke and is also associated with worsened outcomes following a stroke. Peroxiredoxin-2 exerts potent neuroprotective effects against oxidative stress. In the present study,...
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Hemichorea-Hemiballismus Associated with Hyperglycemia: A Case Report

Heo YJ, Jeong HW

Hemichorea-hemiballism (HCHB) associated with nonketotic hyperglycemia is the most common cause of unilateral chorea in patients with type 2 diabetes mellitus. T1-weighted MRI characteristically demonstrates hyperintensity in the contralateral corpus...
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Acute Hyperglycemia Associated with Anti-Cancer Medication

Hwangbo Y, Lee EK

Hyperglycemia during chemotherapy occurs in approximately 10% to 30% of patients. Glucocorticoids and L-asparaginase are well known to cause acute hyperglycemia during chemotherapy. Long-term hyperglycemia is also frequently observed, especially...
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Effects of metformin on hyperglycemia in an experimental model of tacrolimus- and sirolimus-induced diabetic rats

Jin J, Lim SW, Jin L, Yu JH, Kim HS, Chung BH, Yang CW

BACKGROUND/AIMS: Metformin (MET) is a first-line drug for type 2 diabetes mellitus (DM); its effect on new-onset diabetes after transplantation caused by immunosuppressant therapy is unclear. We compared the effects...
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The Relationship between Hyperglycemia and Retinopathy of Prematurity in Very Low Birth Weight Infants

Kim SK, An JW, Lee SH, Oh YK

OBJECTIVE: We aimed to investigate if hyperglycemia is a risk factor of retinopathy of prematurity (ROP) in very low birth weight (VLBW) infants. METHODS: One hundred forty-seven VLBW infants during the...
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A Case of Acute Hyperglycemia Induced by Jerusalem Artichoke in a Patient with Type 2 Diabetes Mellitus

Jang SJ, Kim JM, Bang JH, Jung YG, Jin SJ, Jeong YJ, Kim BK, Kang MY

Jerusalem artichoke (JA) mainly consists of inulin. In many experimental studies, inulin has been shown to be beneficial for decreasing glucose level. Therefore, JA is lately attracting wide attention as...
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Management of Steroid-induced Hyperglycemia

Suh S, Park MK

Steroids are widely used as potent anti-inflammatory and immunosuppressive drugs to treat a wide range of diseases. However, they are also associated with a number of side effects including new-onset...
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