- Hygiene Hypothesis: Related with Sanitation Improvement and Autoimmune Diseases
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Kim KN
- KMID: 2440096
- Korean J Pediatr Infect Dis.
- 2003 May;10(1):37-40.
- doi: 10.14776/kjpid.2003.10.1.37
No abstract available. -
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- Interpretation of the hygiene and microflora hypothesis for allergic diseases through epigenetic epidemiology
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Bae JM
- KMID: 2438461
- Epidemiol Health.
- 2018;40:e2018006.
- doi: 10.4178/epih.e2018006
The hygiene hypothesis (HH) proposed by Strachan in 1989 was expanded to explain the inverse association between the occurrence of allergy disorders and the risk of infectious diseases and parasite... -
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- Immune Disorders and Its Correlation with Gut Microbiome
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Hwang JS, Im CR, Im SH
- KMID: 2424207
- Immune Netw.
- 2012 Aug;12(4):129-138.
Allergic disorders such as atopic dermatitis and asthma are common hyper-immune disorders in industrialized countries. Along with genetic association, environmental factors and gut microbiota have been suggested as major triggering... -
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- The Role of Suppressor T Cells in Mycobacterial Infection
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Ha TY
- KMID: 1482241
- Korean Lepr Bull.
- 2008 Jun;41(1):3-25.
Suppressor T cells (Ts cells) once became probably the most controversial topic in the field of immunology. However, recently the picture has changed dramatically. Suppressor T cells, now less provocatively... -
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- Clinical efficacy and mechanism of probiotics in allergic diseases
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Kim HJ, Kim HY, Lee SY, Seo JH, Lee E, Hong SJ
- KMID: 1493117
- Korean J Pediatr.
- 2013 Sep;56(9):369-376.
- doi: 10.3345/kjp.2013.56.9.369
A complex interplay between genetic and environmental factors partially contributes to the development of allergic diseases by affecting development during prenatal and early life. To explain the dramatic increase in... -
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- Epidemiology of childhood asthma in Asia
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Vichyanond P
- KMID: 2178411
- J Asthma Allergy Clin Immunol.
- 2003 Dec;23(4):725-737.
Asthma is the most common chronic disease in childhood. Over the past 30 years, prevalence of childhood asthma has increased several folds throughout the world. In Asia, such increase has... -
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- Is Mode of Delivery Associated with an Increased Risk for Childhood Asthma?
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Kim BS
- KMID: 2315150
- Pediatr Allergy Respir Dis.
- 2011 Dec;21(4):250-260.
Under the hygiene hypothesis, children born by cesarean section (CS) may consequently have an increased risk of asthma and other allergic diseases. CS has been shown to have a delayed... -
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- Scientific Hypotheses: Writing, Promoting, and Predicting Implications
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Gasparyan , Ayvazyan L, Mukanova U, Yessirkepov M, Kitas GD
- KMID: 2463686
- J Korean Med Sci.
- 2019 Nov;34(45):e300.
- doi: 10.3346/jkms.2019.34.e300
Scientific hypotheses are essential for progress in rapidly developing academic disciplines. Proposing new ideas and hypotheses require thorough analyses of evidence-based data and predictions of the implications. One of the... -
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- Relationship between total IgE and Epstein Barr virus infection during infancy and early childhood
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Lee MK, Cho GH, Kim KS, Jang Y, Yum HY, Han MY
- KMID: 2285863
- J Asthma Allergy Clin Immunol.
- 2002 Dec;22(4):679-684.
BACKGROUND: The 'hygiene hypothesis', the apparent inverse relationship between certain childhood infections and the subsequent development of asthma and atopy, has been gaining attention and is currently now considered one... -
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- Update in the Pathogenesis of Inflammatory Bowel Disease
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Jang BI, Lee SH
- KMID: 2101464
- J Korean Soc Coloproctol.
- 2008 Aug;24(4):302-309.
- doi: 10.3393/jksc.2008.24.4.302
Inflammatory bowel disease (IBD) is a multifactorial disease characterized by abnormal immunologic responses to intestinal antigen, and its causes have not yet been clarified. IBD is known to be due... -
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- The Influence of IgE on Cultured Human Mast Cells
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Frandsen P, Krohn IJ, Hoffmann H, Schiotz PO
- KMID: 2260286
- Allergy Asthma Immunol Res.
- 2013 Nov;5(6):409-414.
- doi: 10.4168/aair.2013.5.6.409
PURPOSE: The mast cell plays a pivotal role in the human immune response. Crosslinking of 2 IgE molecules bound to the high affinity IgE receptor (FcepsilonRI) on the surface of... -
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- IL-12 Production in Lipopolysaccharide- and Dermatophagoides pteronyssinus- Copulsed Monocyte-derived Dendritic Cells
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- KMID: 2234385
- Korean J Asthma Allergy Clin Immunol.
- 2006 Sep;26(3):200-205.
BACKGROUND: Epidemiological studies have provided indirect evidence that exposure to less invasive microbials enhances the development of allergic diseases. Nonetheless, our understanding of the mechanisms that underlie this apparent symbiosis... -
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- The Microbiome and Mental Health: Looking Back, Moving Forward with Lessons from Allergic Diseases
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Logan AC, Jacka FN, Craig JM, Prescott S
- KMID: 2170981
- Clin Psychopharmacol Neurosci.
- 2016 May;14(2):131-147.
- doi: 10.9758/cpn.2016.14.2.131
Relationships between gastrointestinal viscera and human emotions have been documented by virtually all medical traditions known to date. The focus on this relationship has waxed and waned through the centuries,... -
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- Novel Risk Factors for Allergic Rhinitis in Korean Elementary School Children: ARCO-kids Phase II in a Community
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Han DH, Ahn JC, Mun SJ, Park SK, Oh SY, Rhee CS
- KMID: 2260460
- Allergy Asthma Immunol Res.
- 2015 May;7(3):234-240.
- doi: 10.4168/aair.2015.7.3.234
PURPOSE: Allergic rhinitis (AR) is a multifactorial disease whose genetic and environmental risk factors have been studied for decades. Many pediatric studies have pointed out the familial history of allergy,... -
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