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Is platelet-rich plasma improves the anastomotic healing in hyperthermic intraperitoneal chemotherapy with oxaliplatin: an experimental rat study

Buk OF, Ocak S, Genc B, Avcı B, Uzuner HO

PURPOSE: Hyperthermic intraperitoneal chemotherapy (HIPEC) is a novel treatment option for peritoneal surface malignancies. Due to cytotoxic effects of chemotherapeutic agents, anastomosis healing can be impaired and lead to leakage...
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Expression of Muscarinic Receptors and the Effect of Tiotropium Bromide in Aged Mouse Model of Chronic Asthma

Kang JY, Kim IK, Hur J, Kim SC, Lee SY, Kwon SS, Kim YK

BACKGROUND: Efficacy and safety of tiotropium bromide, a muscarinic receptor antagonist, in treatment of asthma have been reported. However, its effect on airway remodeling in chronic asthma of the elderly...
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Prolonged low-dose cyclophosphamide treatment after pulse therapy attenuates lung injury in rats with paraquat intoxication

Gao J, Feng S, Li Y

BACKGROUND/AIMS: This study tested the hypothesis that prolonged low-dose cyclophosphamide (CTX) treatment after pulse therapy attenuate paraquat (PQ)-induced lung injury in rats. METHODS: PQ (25 mg/kg) was administered intraperitoneally to induce...
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Anti-fibrotic effects of Orostachys japonicus A. Berger (Crassulaceae) on hepatic stellate cells and thioacetamide-induced fibrosis in rats

Koppula S, Yum MJ, Kim JS, Shin GM, Chae YJ, Yoon T, Chun CS, Lee JD, Song M

BACKGROUND/OBJECTIVE: Orostachys japonicus A. Berger (Crassulaceae) has been used in traditional herbal medicines in Korea and other Asian countries to treat various diseases, including liver disorders. In the present study,...
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Effect of Rifaximin on Hepatic Fibrosis in Bile Duct-ligated Rat Model

Shin SK, Kwon OS, Lee JJ, Park YH, Choi CS, Jeong SH, Choi DJ, Kim YS, Kim JH

BACKGROUND/AIMS: The translocation of bacteria and their lipopolysaccharides from the gut can promote fibrosis in cirrhotic patients. The aim of this study was to investigate the effects of rifaximin on...
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Sustained-released mixture of vascular endothelial growth factor 165 and fibrin glue strengthens healing of ileal anastomoses in a rabbit model with intraperitoneal infection

Li Z, Wang W, Wang X, Jiang L, Wang F, Liu Q

PURPOSE: To investigate the effects of a sustained-released mixture of vascular endothelial growth factor 165 (VEGF165) and fibrin glue (FG) local administration on postoperative rabbit ileal anastomoses. METHODS: One hundred twenty-eight...
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Comparison of effects of the tacrolimus and cyclosporine A on the colon anastomosis recovery of rats

Uysal E, Dokur M

PURPOSE: This study aims to examine and compare the effects of immunosuppressant cyclosporine A (CsA) and tacrolimus (TAC) on colon anastomosis recovery. METHODS: Forty rats were randomly divided into 4 groups....
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Histological and biochemical study of the superficial abdominal fascia and its implication in obesity

Pandey AK, Kumar P, Aithal SK, Kotian SR, Thittamaranahalli H, Bangera H, Prasad K, Souza AD

The advancement of liposculpturing and fascial flaps in reconstructive surgery has renewed interest in the superficial fascia of abdomen. Its histological and biochemical composition may play a vital role in...
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Decreased Prolidase Activity in Patients with Posttraumatic Stress Disorder

Demir S, Bulut M, Atli A, Kaplan I, Kaya MC, Bez Y, Özdemir P, Sır A

OBJECTIVE: Many neurochemical systems have been implicated in the development of Posttraumatic Stress Disorder (PTSD). The prolidase enzyme is a cytosolic exopeptidase that detaches proline or hydroxyproline from the carboxyl...
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The effects of scalpel, harmonic scalpel and monopolar electrocautery on the healing of colonic anastomosis after colonic resection

Karaca G, Pekcici MR, Altunkaya , Fidanci V, Kilinc A, Ozer H, Tekeli A, Aydinuraz , Guler O

PURPOSE: In our study, the effects of harmonic scalpel, scalpel, and monopolar electrocautery usage on the health and healing of colon anastomosis after resection was investigated. METHODS: In this study, 120...
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Effects of a Glutamine Enema on Anastomotic Healing in an Animal Colon Anastomosis Model

Habibi M, Oner OZ, Oruc MT, Bulbuller , Ozdem S, Ozdemir S, Alikanooglu AS, Karakoyun , Dogan U, Ongen A, Koc U

PURPOSE: Anastomotic leakage in colorectal surgery is a very important issue. Although many studies have shown the positive effects of enteral glutamine (Gln) on anastomotic healing, none has assessed the...
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The effects of ventilation with high density oxygen on the strength of gastrointestinal anastomosis

Eker T, Genc V, Sevim Y, Cumaogullari O, Ozcelik M, Kocaay AF, Ensari CO, Pasaoglu O

PURPOSE: The aim of our study is to evaluate the effects of administration of perioperative supplemental oxygen on anastomoses. METHODS: Forty male Wistar albino rats were used in the study and...
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Passive Skeletal Muscle Excursion after Tendon Rupture Correlates with Increased Collagen Content in Muscle

Koh IH, Kang HJ, Jeon SW, Park JH, Choi YR

PURPOSE: This study was designed to measure time-dependent changes in muscle excursion and collagen content after tenotomy, and to analyze the correlation between muscle excursion and collagen content in a...
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Transforming Growth Factor-beta Type I Receptor Inhibitor Induces Functional and Morphologic Recovery in a Rat Model of Erectile Dysfunction and Cavernous Fibrosis

Ryu JK, Oh SM, Jin HR, Song KM, Kwon MH, Kim DK, Suh JK

PURPOSE: To examine the effectiveness of small-molecule inhibitor of transforming growth factor-beta (TGF-beta) type I receptor, an activin receptor-like kinase 5 (ALK5), on erectile dysfunction (ED) in a rat model...
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Incidence of hypocalcemia and its changes of biochemical parameters in periparturient cows

Shu S, Xia C, Xu C, Zhang H, Wu L

  • KMID: 1435801
  • Korean J Vet Res.
  • 2012 Mar;52(1):57-59.
In this study, we investigate the status of calcium (Ca) homeostasis at parturition in three dairy farms (I, II, and III), Heilongjiang, China. Twenty multiparous Holstein cows from each farm...
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The Antifibrotic Effects of alpha-Tocotrienols in Primary Cultured Orbital Fibroblasts from Thyroid-Associated Ophthalmopathy Patients

Kim SJ, Kang HK, Kang SM

  • KMID: 2338050
  • J Korean Ophthalmol Soc.
  • 2012 Feb;53(2):323-332.
PURPOSE: To evaluate the antiproliferative and antifibrotic effects of alpha-tocotrienols in primary cultured orbital fibroblasts from thyroid-associated ophthalmopathy (TAO) patients. METHODS: Orbital fibroblasts were cultured (5 eyes from TAO patients, 5...
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Antifibrotic activity a fermentation filtrate of Ganoderma lucidum

Kwon SC, Kim YB

The effects of a fermentation filtrate of Ganoderma lucidum (FGL) on carbon tetrachloride (CCl4)-induced hepatic fibrosis were investigated in rats. Male Sprague-Dawley rats were orally administered with FGL (20 or...
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Statistical Approach to Test Construct Validity and Obtain Weights for the Children's Dietary Life Recognition and Practice Index

Kwon S, Kim HY, Lee JS, Kwak TK, Chung HR, Choi YS, Kang MH

Constructs with seven latent evaluation indicators and 18 observable survey questions were developed by food and nutrition experts to calculate a food safety recognition and practice index for children. The...
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Relationship Between Depression Anxiety Stress Scale (DASS) and Urinary Hydroxyproline and Proline Concentrations in Hospital Workers

Lee KW, Kim SJ, Park JB, Lee KJ

OBJECTIVES: Although increased reactive oxygen species (ROS) is caused by stress accelerates collagen degradation, there was no data on the relationship between stress and urinary hydroxyproline (Hyp) and proline (Pro),...
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Effect of dietary supplementation of grape skin and seeds on liver fibrosis induced by dimethylnitrosamine in rats

Shin MO, Moon JO

  • KMID: 2313468
  • Nutr Res Pract.
  • 2010 Oct;4(5):369-374.
Grape is one of the most popular and widely cultivated fruits in the world. Although grape skin and seeds are waste product of the winery and grape juice industry, these...
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