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Isoginkgetin Inhibits Insulin-Like Growth Factor-1-Induced Sebum Production in Cultured Human Sebocytes

Hwang YL, Lee MH, Oh HI, Kim HJ, Lim CA, Lee JH, Kim CD

No abstract available.
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Potential Role of Cytosolic RNA Sensor MDA5 as an Inhibitor for Keratinocyte Differentiation in the Pathogenesis of Psoriasis

Hong DK, Choi MR, Hwang YL, Lee JK, Lee Y, Seo YJ, Kim S, Lee YH, Kim CD, Lee JH

Background: Psoriasis is a chronic inflammatory skin disease. The etiology of psoriasis is not fully understood, but the genetic background is considered to be the most important factor. To date,...
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Cedrol Enhances Extracellular Matrix Production in Dermal Fibroblasts in a MAPK-Dependent Manner

Jin MH, Park SG, Hwang YL, Lee MH, Jeong NJ, Roh SS, Lee Y, Kim CD, Lee JH

BACKGROUND: The extracellular matrix (ECM) produced by dermal fibroblasts supports skin structure, and degradation and/or reduced production of ECM are the main causes of wrinkle formation. OBJECTIVE: The aim of this...
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Novel Mechanism of Action of Dutasteride for Inducing Hair Growth in Patients with Female-Pattern Hair Loss

Kim S, Hwang YL, Yim SH, Hong D, Choi CW, Jung KE, Seo YJ, Kim CD, Shin J, Lee Y

  • KMID: 2502820
  • Korean J Dermatol.
  • 2020 May;58(4):231-238.
Background: Female-pattern hair loss (FPHL) is a common hair loss disorder in women. The various treatments include topical minoxidil and 17α-estradiol, as well as oral anti-androgens. However, the clinical efficacy...
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A Novel Compound Rasatiol Isolated from Raphanus sativus Has a Potential to Enhance Extracellular Matrix Synthesis in Dermal Fibroblasts

Roh SS, Park SB, Park SM, Choi BW, Lee MH, Hwang YL, Kim CH, Jeong HA, Kim CD, Lee JH

BACKGROUND: The fibrous proteins of extracellular matrix (ECM) produced by dermal fibroblast contributes to the maintenance of connective tissue integrity. OBJECTIVE: This study is carried out to identify the bioactive ingredient...
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Stimulation of the Extracellular Matrix Production in Dermal Fibroblasts by Velvet Antler Extract

Roh SS, Lee MH, Hwang YL, Song HH, Jin MH, Park SG, Lee CK, Kim CD, Yoon TJ, Lee JH

BACKGROUND: Fibroblasts produce many components of the extracellular matrix (ECM) and so they contribute to the maintenance of connective tissue integrity. OBJECTIVE: The aim of this study is to evaluate the...
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Inhibition of Insulin-Like Growth Factor-1–Induced Sebum Production by Bilobetin in Cultured Human Sebocytes

Wang C, Hwang YL, Li XM, Kim SJ, Zhu MJ, Lee JH, Jiang RH, Kim CD

BACKGROUND: Sebocytes are the major cells of sebaceous gland. The essential role of sebocytes is the production of sebum, a specific lipid mixture, that covers the body surface and provides...
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