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Recombinant proteins of spike protein of SARS-CoV-2 with the Omicron receptor-binding domain induce production of highly Omicron-specific neutralizing antibodies

Kang H, Kim D, Min K, Park M, Kim SH, Sohn EJ, Choi BH, Hwang I

Various vaccines have been developed to fight severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus responsible for the coronavirus disease 2019 pandemic. However, new variants of SARS-CoV-2 undermine the effort...
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Safety monitoring of COVID-19 vaccination among adolescents aged 12 to 17 years old in the Republic of Korea

Kim S, Hwang I, Ko M, Kwon Y, Lee YK

Objectives This study aimed to disseminate information on coronavirus disease 2019 (COVID-19) vaccine safety among adolescents aged 12 to 17 years in the Republic of Korea. Methods Two databases were used...
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Added Value of Contrast Leakage Information over the CBV Value of DSC Perfusion MRI to Differentiate between Pseudoprogression and True Progression after Concurrent Chemoradiotherapy in Glioblastoma Patients

Pak E, Choi SH, Park CK, Kim TM, Park SH, Won JK, Lee JH, Lee ST, Hwang I, Yoo RE, Kang KM, Yun TJ

Purpose: To evaluate whether the added value of contrast leakage information from dynamic susceptibility contrast magnetic resonance imaging (DSC MRI) is a better prognostic imaging biomarker than the cerebral blood...
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Myelin Content in Mild Traumatic Brain Injury Patients with Post-Concussion Syndrome: Quantitative Assessment with a Multidynamic Multiecho Sequence

Yoo RE, Choi SH, Youn SW, Hwang M, Kim E, Oh BM, Lee JY, Hwang I, Kang KM, Yun TJ, Kim Jh, Sohn CH

Objective: This study aimed to explore the myelin volume change in patients with mild traumatic brain injury (mTBI) with post-concussion syndrome (PCS) using a multidynamic multiecho (MDME) sequence and automatic...
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Computational modeling of atrial fibrillation

 Kwon O, Hwang I, Pak H

With the aging society, the prevalence of atrial fibrillation (AF) continues to increase. Nevertheless, there are still limitations in antiarrhythmic drugs (AAD) or catheter interventions for AF. If it is...
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Analysis  of  Research  Trends  in  the  Korean  Journal  of  Medical  Education and  Korean  Medical  Education  Review  Using  Keyword  Network  Analysis

Lee A, Kim SG, Hwang I

The aim of this study was to analyze the research trends in articles published in the Korean Journal of Medical Education (KJME) and Korean Medical Education Review (KMER) using keyword...
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Assessment of Mild Cognitive Impairment in Elderly Subjects Using a Fully Automated Brain Segmentation Software

Kwon C, Kang KM, Byun MS, Yi D, Song H, Lee JY, Hwang I, Yoo RE, Yun TJ, Choi SH, Kim Jh, Sohn CH, Lee DY, for the KBASE Research Group

Purpose: Mild cognitive impairment (MCI) is a prodromal stage of Alzheimer's disease (AD). Brain atrophy in this disease spectrum begins in the medial temporal lobe structure, which can be recognized...
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Metastatic leiomyosarcoma of the thyroid gland: cytologic findings and differential diagnosis

Lee J, Cho Y, Choi KH, Hwang I, Oh YL

Metastatic leiomyosarcoma to the thyroid is an extremely rare occurrence, and only 18 cases have been reported. Here, we report a case of a 37-year-old woman who presented with multiple...
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Prediction of Prognosis in Glioblastoma Using Radiomics Features of Dynamic Contrast-Enhanced MRI

Pak E, Choi KS, Choi SH, Park CK, Kim TM, Park SH, Lee JH, Lee ST, Hwang I, Yoo RE, Kang KM, Yun TJ, Kim JH, Sohn CH

Objective: To develop a radiomics risk score based on dynamic contrast-enhanced (DCE) MRI for prognosis prediction in patients with glioblastoma. Materials and Methods: One hundred and fifty patients (92 male [61.3%];...
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COVID-19 vaccine safety monitoring in the Republic of Korea: February 26, 2021 to April 30, 2021

Oh Hk, Kim EK, Hwang I, Kim TE, Lee Yk, Lee E, Lee YK

Objectives: On February 26, 2021, coronavirus disease 2019 (COVID-19) vaccination was started for high-priority groups based on the recommendation of the Advisory Committee on Immunization Practices with 2 available COVID-19...
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Enuresis as a Presenting Symptom of Graves’ Disease: A Case Report

Hwang I, Park E, Lee HJ

Enuresis is intermittent urinary incontinence during sleep at night in children aged 5 years or older. The main pathophysiology of enuresis involves nocturnal polyuria, abnormal sleep arousal, and low functional...
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Cerebrovascular Reservoir and Arterial Transit Time Changes Assessed by Acetazolamide-Challenged Multi-Phase Arterial Spin Labeling Perfusion MRI in Chronic Cerebrovascular Steno-Occlusive Disease

Hwang I, Sohn CH, Jung KH, Yeon EK, Lee JY, Yoo RE, Kang KM, Yun TJ, Choi SH, Kim Jh

Purpose: To explore cerebrovascular reservoir (CVR) and arterial transit time (ATT) changes using acetazolamide-challenged multi-phase arterial spin labeling (MP-ASL) perfusion-weighted MRI in chronic cerebrovascular steno-occlusive disease. Materials and Methods: This retrospective...
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Effects of Program to Promote Obesity Prevention Behaviors on Pre-Schoolers: Focused on Kindergartener in Korea

Hwang I, Bang KS

Purpose: This study aimed to develop a program to promote obesity prevention behaviors for pre-schoolers and to confirm the effectiveness of the program in Korea. Methods: The program comprised 8...
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Blood-Brain Barrier Disruption in Mild Traumatic Brain Injury Patients with Post-Concussion Syndrome: Evaluation with Region-Based Quantification of Dynamic Contrast-Enhanced MR Imaging Parameters Using Automatic Whole-Brain Segmentation

Yoen H, Yoo RE, Choi SH, Kim E, Oh BM, Yang D, Hwang I, Kang KM, Yun TJ, Kim Jh, Sohn CH

Objective: This study aimed to investigate the blood-brain barrier (BBB) disruption in mild traumatic brain injury (mTBI) patients with post-concussion syndrome (PCS) using dynamic contrast-enhanced (DCE) magnetic resonance (MR) imaging...
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Author's Reply to Heart Transplantation to Fulminant Myocarditis during COVID-19 Outbreak

Kim IC, Hwang I, Kim YS, Kim JB

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Salivary biomarkers in oral squamous cell carcinoma

Nguyen TTH, Sodnom-Ish B, Choi SW, Jung HI, Cho J, Hwang I, Kim SM

In disease diagnostics and health surveillance, the use of saliva has potential because its collection is convenient and noninvasive. Over the past two decades, the development of salivary utilization for...
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Accuracy and clinical feasibility of 3D‑myocardial thickness map measured by cardiac computed tomogram

Kwon O, Lee J, Lim S, Park J, Han H, Yang S, Hwang I, Yu H, Kim T, Uhm J, Joung B, Lee M, Pak H

Background: Although myocardial thickness is an important variable for therapeutic catheter ablation of cardiac arrhythmias, quantification of wall thickness has been overlooked. We developed a software (AMBER) that measures 3D-myocardial...
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Successful Heart Transplantation to a Fulminant Myocarditis Patient during COVID-19 Outbreak – Lessons Learned

Kim IC, Hwang I, Kim YS, Kim JB

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Clinical and genetic relationships between the QTc interval and risk of a stroke among atrial fibrillation patients undergoing catheter ablation

Hong M, Chun K, Hwang I, Yu H, Kim T, Uhm J, Joung B, Lee M, Pak H

Background and objectives: A prolonged QTc interval is associated with an increased risk of a stroke or atrial fibrillation (AF). However, its direct causal relationship with AF associated a stroke...
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Ultrasonographic Indeterminate Lymph Nodes inPreoperative Thyroid Cancer Patients: Malignancy Riskand Ultrasonographic Findings Predictive of Malignancy

Yoo RE, Kim Jh, Bae JM, Hwang I, Kang KM, Yun TJ, Choi SH, Sohn CH, Rhim JH, Park SW

Objective: Proper management of lymph nodes (LNs) with ultrasonographic (US) indeterminate features in thyroid cancer patients remains elusive. We aimed to evaluate the malignancy risk and US findings predictive of malignancy...
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