- Lineage-specific Expression of miR-200 Family in Human Embryonic Stem Cells during In Vitro Differentiation
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Kim Y, Kim N, Park SW, Kim H, Park HJ, Han YM
- KMID: 2384599
- Int J Stem Cells.
- 2017 May;10(1):28-37.
- doi: 10.15283/ijsc17013
Although microRNAs have emerged as key regulators in diverse cellular processes, the roles of microRNAs are poorly understood in human embryonic stem cells (hESCs) during differentiation into specialized cell types.... -
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- Maintenance of hPSCs under Xeno-Free and Chemically Defined Culture Conditions
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Lim JJ, Kim HJ, Rhie BH, Lee MR, Choi MJ, Hong SH, Kim KS
- KMID: 2465889
- Int J Stem Cells.
- 2019 Nov;12(3):484-496.
- doi: 10.15283/ijsc19090
Previously, the majority of human embryonic stem cells and human induced pluripotent stem cells have been derived on feeder layers and chemically undefined medium. Those media components related to feeder... -
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- Human Embryonic Stem Cell Derived from Early Stage Fertilized Ovum: Non Immunogenic and Universal, Neuronal and Non-neuronal Cell Lines
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Shroff G, Srivastav , Shroff R
- KMID: 2413506
- Int J Stem Cells.
- 2018 Jun;11(1):105-110.
- doi: 10.15283/ijsc17064
BACKGROUND: Human embryonic stem cells (hESCs) have the potential to treat various human disorders currently labeled as incurable and/or terminal illness. However, the fear that the patients' immune system would... -
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- Generation of hematopoietic stem cells from human embryonic stem cells using a defined, stepwise, serum-free, and serum replacement-free monolayer culture method
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Kim SJ, Jung JW, Ha HY, Koo SK, Kim EG, Kim JH
- KMID: 2375202
- Blood Res.
- 2017 Mar;52(1):37-43.
- doi: 10.5045/br.2017.52.1.37
BACKGROUND: Embryonic stem cells (ESCs) can be expanded infinitely in vitro and have the potential to differentiate into hematopoietic stem cells (HSCs); thus, they are considered a useful source of... -
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- Functional Comparison of Human Embryonic Stem Cells and Induced Pluripotent Stem Cells as Sources of Hepatocyte-Like Cells
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Jeong J, Kim KN, Chung MS, Kim HJ
- KMID: 2360886
- Tissue Eng Regen Med.
- 2016 Dec;13(6):740-749.
- doi: 10.1007/s13770-016-0094-y
Pluripotent stem cells can differentiate into many cell types including mature hepatocytes, and can be used in the development of new drugs, treatment of diseases, and in basic research. In... -
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- Clean-Up Human Embryonic Stem Cell Lines Using Humanized Culture Condition
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Baek JA, Seol HW, Jung J, Kim HS, Oh SK, Choi YM
- KMID: 2394979
- Tissue Eng Regen Med.
- 2017 Aug;14(4):453-464.
- doi: 10.1007/s13770-017-0053-2
Human embryonic stem cell (hESC) culture system has been changing culture conditions from conventional to xeno-free for therapeutic cell applications, and N-glycolylneuraminic acid (Neu5Gc) could be a useful indicator of... -
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- Production of Transfusable Red Blood Cells from Stem Cells
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Kim HO
- KMID: 2368783
- Korean J Blood Transfus.
- 2016 Dec;27(3):209-219.
- doi: 10.17945/kjbt.2016.27.3.209
Blood transfusion is a well-established cell therapy. However, blood available for transfusion is a limited resource and is available only through donations by healthy volunteers. Moreover, the perpetual and widespread... -
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- Improved Transfection Efficiency and Metabolic Activity in Human Embryonic Stem Cell Using Non-Enzymatic Method
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Kim CY, Hwang IK, Kang C, Chung EB, Jung CR, Oh H, Jeong YH, Moon SH, Kim JS, Hong KS, Park JH, Chung HM
- KMID: 2429547
- Int J Stem Cells.
- 2018 Nov;11(2):149-156.
- doi: 10.15283/ijsc18037
Human embryonic stem cells (hESCs) are pluripotent cells widely used in conventional and regenerative medicine due to their ability to self-renew, proliferate and differentiate. Recently, genetic modification of stem cells... -
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- In vivo Evaluation of Human Embryonic Stem Cells Isolated by 57-C11 Monoclonal Antibody
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Kim WT, Lee HM, Kim MK, Choi HS, Ryu CJ
- KMID: 2362520
- Int J Stem Cells.
- 2016 Nov;9(2):264-270.
- doi: 10.15283/ijsc16052
BACKGROUND: The normal cells derived from human embryonic stem cells (hESCs) are regarded as substitutes for damaged or dysfunctional adult cells. However, tumorigenicity of hESCs remains a major challenge in... -
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- Differential MicroRNA Expression Profile of Human Embryonic Stem Cell-Derived Cardiac Lineage Cells
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Kim YY, Min H, Kim H, Choi YM, Liu HC, Ku SY
- KMID: 2377346
- Tissue Eng Regen Med.
- 2017 Apr;14(2):163-169.
- doi: 10.1007/s13770-017-0051-4
MicroRNAs (miRNAs) are small non-coding RNA molecules that participate in transcriptional and post-transcriptional regulation of gene expression. miRNAs have numerous roles in cellular function including embryonic development. Human embryonic stem... -
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- Directing Human Embryonic Stem Cells towards Functional Endothelial Cells Easily and without Purification
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Gil CH, Ki BS, Seo J, Choi JJ, Kim H, Kim IG, Jung AR, Lee WY, Choi Y, Park K, Moon SH, Chung HM
- KMID: 2361012
- Tissue Eng Regen Med.
- 2016 Jun;13(3):274-283.
- doi: 10.1007/s13770-016-9076-3
Hemangioblasts or blood islands only arise in early development thereby the sources to obtain these bi-potential cells are limited. While previous studies have isolated both lineages in vitro through the... -
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- Two Fronts of Future Medicine
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Kim JW
- KMID: 2431874
- Int Neurourol J.
- 2018 Jul;22(Suppl 2):S63-S64.
- doi: 10.5213/inj.1820edi.004
No abstract available. -
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- The Therapeutic Effect of Human Embryonic Stem Cell-Derived Multipotent Mesenchymal Stem Cells on Chemical-Induced Cystitis in Rats
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Lee SW, Ryu CM, Shin JH, Choi D, Kim A, Yu HY, Han JY, Lee HY, Lim J, Kim YH, Heo J, Lee S, Ju H, Kim S, Hong KS, Han JY, Song M, Chung HM, Kim JK, Shin DM, Choo MS
- KMID: 2405270
- Int Neurourol J.
- 2018 Jan;22(Suppl 1):S34-S45.
- doi: 10.5213/inj.1836014.007
PURPOSE: To evaluate the therapeutic effect of human embryonic stem cell (hESC)-derived multipotent mesenchymal stem cells (M-MSCs) on ketamine-induced cystitis (KC) in rats. METHODS: To induce KC, 10-week-old female rats were... -
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- Functional Recovery Following the Transplantation of Olfactory Ensheathing Cells in Rat Spinal Cord Injury Model
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Muniswami , Tharion G
- KMID: 2430632
- Asian Spine J.
- 2018 Dec;12(6):998-1009.
- doi: 10.31616/asj.2018.12.6.998
STUDY DESIGN: Olfactory ensheathing cells (OECs) from rat olfactory mucosa were cultured, characterized, and transplanted into a rat model of spinal cord injury (SCI). PURPOSE: To evaluate different doses of OECs... -
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