- Identification of a putative transactivation domain in human Nanog
-
Oh JH, Do HJ, Yang HM, Moon SY, Cha KY, Chung HM, Kim JH
- KMID: 1056238
- Exp Mol Med.
- 2005 Jun;37(3):250-254.
Nanog is a newly identified divergent homeodomain protein that directs the infinite propagation and sustains the pluripotency of embryonic stem cells. It has been reported that murine Nanog has two... -
- CITED
-
- Close
- SHARE
-
- Close
- B-cell translocation gene 2 positively regulates GLP-1-stimulated insulin secretion via induction of PDX-1 in pancreatic beta-cells
-
Hwang SL, Kwon O, Kim SG, Lee IK, Kim YD
- KMID: 2154244
- Exp Mol Med.
- 2013 May;45(5):e25.
Glucagon-like peptide-1 (GLP-1) is a potent glucoincretin hormone and an important agent for the treatment of type 2 diabetes. Here we demonstrate that B-cell translocation gene 2 (BTG2) is a... -
- CITED
-
- Close
- SHARE
-
- Close
- A Family with Axenfeld-Rieger Syndrome: Report of the Clinical and Genetic Findings
-
Yang HJ, Lee YK, Joo CK, Moon JI, Mok JW, Park MH
- KMID: 2363769
- Korean J Ophthalmol.
- 2015 Aug;29(4):249-255.
- doi: 10.3341/kjo.2015.29.4.249
PURPOSE: To describe clinical findings in a Korean family with Axenfeld-Rieger syndrome. METHODS: A retrospective review of clinical data about patients with diagnosed Axenfeld-Rieger syndrome. Five affected members of the family... -
- CITED
-
- Close
- SHARE
-
- Close
- Transcriptional regulation of Zic3 by heterodimeric AP-1(c-Jun/c-Fos) during Xenopus development
-
Lee SY, Lee HS, Moon JS, Kim JI, Park JB, Lee JY, Park MJ, Kim J
- KMID: 1123768
- Exp Mol Med.
- 2004 Oct;36(5):468-475.
The heterodimeric c-Jun/c-Fos, an activator protein-1 (AP-1) has been implicated in mesoderm induction (Dong et al., 1996; Kim et al., 1998) whereas the homodimer of c-Jun was reported to be... -
- CITED
-
- Close
- SHARE
-
- Close
- A Case of Congenital Central Hypoventilation Syndrome with PHOX2B Gene Mutation in a Korean Neonate
-
Kwon KA, Park SE, Byun SY, Kim SY, Hwang SH
- KMID: 1714051
- J Korean Med Sci.
- 2010 Aug;25(8):1237-1240.
- doi: 10.3346/jkms.2010.25.8.1237
Congenital central hypoventilation syndrome (CCHS) is a life-threatening disorder with apnea and cyanosis during sleep requiring immediate endotracheal intubation during the first day of life. The PHOX2B gene has been... -
- CITED
-
- Close
- SHARE
-
- Close
- Haddad Syndrome with PHOX2B Gene Mutation in a Korean Infant
-
Lee CW, Lee JH, Jung EY, Choi SO, Kim CS, Lee SL, Kim DK
- KMID: 1782126
- J Korean Med Sci.
- 2011 Feb;26(2):312-315.
- doi: 10.3346/jkms.2011.26.2.312
Congenital central hypoventilation syndrome with Hirschsprung's disease, also known as Haddad syndrome, is an extremely rare disorder with variable symptoms. Recent studies described that congenital central hypoventilation syndrome had deep... -
- CITED
-
- Close
- SHARE
-
- Close
- Circadian regulation of low density lipoprotein receptor promoter activity by CLOCK/BMAL1, Hes1 and Hes6
-
Lee YJ, Han DH, Pak YK, Cho S
- KMID: 1401756
- Exp Mol Med.
- 2012 Nov;44(11):642-652.
Low density lipoprotein receptor (LDLR) plays an important role in the cholesterol homeostasis. We examined the possible circadian regulation of LDLR and mechanism(s) underlying it. In mice, blood glucose and... -
- CITED
-
- Close
- SHARE
-
- Close
- A Synonymous Genetic Alteration of LMX1B in a Family with Nail-Patella Syndrome
-
Ham JH, Shin SJ, Joo KR, Park SM, Sung HY, Kim JS, Choi JS, Choi YJ, Song HC, Choi EJ
- KMID: 1717953
- Korean J Intern Med.
- 2009 Sep;24(3):274-278.
- doi: 10.3904/kjim.2009.24.3.274
The gene responsible for nail-patella syndrome, LMX1B, has recently been identified on chromosome 9q. Here we present a patient with nail-patella syndrome and an autosomal dominant pattern of inheritance. A... -
- CITED
-
- Close
- SHARE
-
- Close
- Expression of Cdx-2 Homeobox Gene in Intestinal Metaplasia and Gastric Adenocarcinoma
-
Paik CH, Han DS, Lee SH, Chung YW, Kim JP, Sohn JH, Hahm JS, Oh YH, Park YU
- KMID: 1113418
- Korean J Gastroenterol.
- 2004 Oct;44(4):186-192.
BACKGROUND/AIMS: The Cdx-1 and Cdx-2 genes are intestinal transcription factors that may be involved in the regulation of proliferation and differentiation of intestinal epithelial cells. The Cdx-1 and Cdx-2... -
- CITED
-
- Close
- SHARE
-
- Close
- Point Mutation of Hoxd12 in Mice
-
Cho KW, Kim JY, Cho JW, Cho KH, Song CW, Jung HS
- KMID: 1782945
- Yonsei Med J.
- 2008 Dec;49(6):965-972.
- doi: 10.3349/ymj.2008.49.6.965
PURPOSE: Genes of the HoxD cluster play a major role in vertebrate limb development, and changes that modify the Hoxd12 locus affect other genes also, suggesting that HoxD function is... -
- CITED
-
- Close
- SHARE
-
- Close
- Clinico-Genetic Study of Nail-Patella Syndrome
-
Lee BH, Cho TJ, Choi HJ, Kang HK, Lim IS, Park YH, Ha IS, Choi Y, Cheong HI
- KMID: 1778145
- J Korean Med Sci.
- 2009 Jan;24(Suppl 1):S82-S86.
- doi: 10.3346/jkms.2009.24.S1.S82
Nail-patella syndrome (NPS) is an autosomal dominant disease that typically involves the nails, knees, elbows and the presence of iliac horns. In addition, some patients develop glomerulopathy or adult-onset glaucoma.... -
- CITED
-
- Close
- SHARE
-
- Close
- CDX1 and CDX2 Expression in Intestinal Metaplasia, Dysplasia and Gastric Cancer
-
Kang JM, Lee BH, Kim N, Lee HS, Lee HE, Park JH, Kim JS, Jung HC, Song IS
- KMID: 1777864
- J Korean Med Sci.
- 2011 May;26(5):647-653.
- doi: 10.3346/jkms.2011.26.5.647
Intestinal metaplasia (IM) has been regarded as a premalignant condition. However, the pathogenesis of IM is not fully understood. The aim of this study was to evaluate the role of... -
- CITED
-
- Close
- SHARE
-
- Close
- Level of HOXA5 Hypermethylation in Acute Myeloid Leukemia is Associated with Short-term Outcome
-
Kim SY, Hwang SH, Song EJ, Shin HJ, Jung JS, Lee EY
- KMID: 1022036
- Korean J Lab Med.
- 2010 Oct;30(5):469-473.
- doi: 10.3343/kjlm.2010.30.5.469
Hypermethylation of the homeobox (HOX) gene promoter leads to decreased expression of the gene during tumor development and is thought to be correlated with the clinical outcome in leukemia. In... -
- CITED
-
- Close
- SHARE
-
- Close
