- Histone Acetylation Level and Histone Acetyltransferase/Deacetylase Activity in Ejaculated Sperm from Normozoospermic Men
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Kim JH, Jee BC, Lee JM, Suh CS, Kim SH
- KMID: 1799499
- Yonsei Med J.
- 2014 Sep;55(5):1333-1340.
- doi: 10.3349/ymj.2014.55.5.1333
PURPOSE: The aim of this work was to evaluate nuclear histone acetylation level and total histone acetyltransferase (HAT) and deacetylase (HDAC) activity in ejaculated sperm and their relevance to conventional... -
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- Epigenetic Cross-Talk between DNA Methylation and Histone Modifications in Human Cancers
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Kondo Y
- KMID: 1758603
- Yonsei Med J.
- 2009 Aug;50(4):455-463.
- doi: 10.3349/ymj.2009.50.4.455
DNA methylation, histone modifications, and the chromatin structure are profoundly altered in human cancers. The silencing of cancer-related genes by these epigenetic regulators is recognized as a key mechanism in... -
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- Histone Deacetylases and Their Regulatory MicroRNAs in Hepatocarcinogenesis
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Kim HS, Shen Q, Nam SW
- KMID: 2344168
- J Korean Med Sci.
- 2015 Oct;30(10):1375-1380.
- doi: 10.3346/jkms.2015.30.10.1375
A growing body of evidence suggests that epigenetic modifications are promising potential mechanisms in cancer research. Among the molecules that mediate epigenetic mechanisms, histone deacetylases (HDACs) are critical regulators of... -
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- CpG Array Analysis of Histone H3 Lysine 4 Trimethylation by Chromatin Immunoprecipitation Linked to Microarrays Analysis in Peripheral Blood Mononuclear Cells of IgA Nephropathy Patients
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Qi S, Sui W, Yang M, Chen J, Dai Y
- KMID: 1120206
- Yonsei Med J.
- 2012 Mar;53(2):377-385.
- doi: 10.3349/ymj.2012.53.2.377
PURPOSE: The purpose of the present study was to investigate the aberrance of histone H3 lysine 4 trimethylation (H3K4me3) in patients with IgA Nephropathy (IgAN). MATERIALS AND METHODS: In this study,... -
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- Repression of TNF-alpha-induced IL-8 expression by the glucocorticoid receptor-beta involves inhibition of histone H4 acetylation
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Kim SH, Kim DH, Lavender P, Seo JH, Kim YS, Park JS, Kwak SJ, Jee YK
- KMID: 1123803
- Exp Mol Med.
- 2009 May;41(5):297-306.
- doi: 10.3858/emm.2009.41.5.033
Increased expression of a number of proinflammatory genes, including IL-8, is associated with inflammatory conditions such as asthma. Glucocorticoid receptor (GR)beta, one of the GR isoforms, has been suggested to... -
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- Cytosolic accumulation of gammaH2AX is associated with tropomyosin-related kinase A-induced cell death in U2OS cells
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Jung EJ, Kim CW, Kim DR
- KMID: 756329
- Exp Mol Med.
- 2008 Jun;40(3):276-285.
- doi: 10.3858/emm.2008.40.3.276
Tropomyosin-related kinase A (TrkA) plays an important role in cell survival, differentiation, and apoptosis in various neuronal and nonneuronal cell types. Here we show that TrkA overexpression by the Tet-On... -
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- Coordinated change of a ratio of methylated H3-Iysine 4 or acetylated H3 to acetylated H4 and DNA methylation is associated with tissue-specific gene expression in cloned pig
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Kang JK, Park KW, Chung YG, You JS, Kim YK, Lee SH, Hong SP, Choi KM, Heo KN, Seol JG, Lee JH, Jin DI, Park CS, Seo JS, Lee HW, Han JW
- KMID: 1103684
- Exp Mol Med.
- 2007 Feb;39(1):84-96.
Various cell types in higher multicellular organisms are genetically homogenous, but are functionally and morphologically heterogeneous due to the differential expression of genes during development, which appears to be controlled... -
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