- Modulation of gene expression dynamics by co-transcriptional histone methylations
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Woo H, Ha SD, Lee SB, Buratowski S, Kim T
- KMID: 2382717
- Exp Mol Med.
- 2017 Apr;49(4):e326.
- doi: 10.1038/emm.2017.19
Co-transcriptional methylations of histone H3 at lysines 4 and 36, highly conserved methyl marks from yeast to humans, have profound roles in regulation of histone acetylation. These modifications function to... -
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- Free fatty acid-induced histone acetyltransferase activity accelerates lipid accumulation in HepG2 cells
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Chung S, Hwang JT, Park JH, Choi HK
- KMID: 2453283
- Nutr Res Pract.
- 2019 Jun;13(3):196-204.
- doi: 10.4162/nrp.2019.13.3.196
BACKGROUND/OBJECTIVES: Non-alcoholic fatty liver disease (NAFLD) is a common metabolic disease triggered by epigenetic alterations, including lysine acetylation at histone or non-histone proteins, affecting the stability or transcription of lipogenic... -
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- The Histone Acetyltransferase hMOF is Overexpressed in Non-small Cell Lung Carcinoma
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Song JS, Chun SM, Lee JY, Kim DK, Kim YH, Jang SJ
- KMID: 2277503
- Korean J Pathol.
- 2011 Aug;45(4):386-396.
BACKGROUND: One of the histone acetyltransferases (HATs) family of proteins, human MOF (hMOF, MYST1), is involved in histone H4 acetylation, particularly at lysine 16 (H4K16Ac), an epigenetic mark of active... -
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- Histone Acetylation Level and Histone Acetyltransferase/Deacetylase Activity in Ejaculated Sperm from Normozoospermic Men
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Kim JH, Jee BC, Lee JM, Suh CS, Kim SH
- KMID: 1799499
- Yonsei Med J.
- 2014 Sep;55(5):1333-1340.
- doi: 10.3349/ymj.2014.55.5.1333
PURPOSE: The aim of this work was to evaluate nuclear histone acetylation level and total histone acetyltransferase (HAT) and deacetylase (HDAC) activity in ejaculated sperm and their relevance to conventional... -
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- Expression of HAT1 and HDAC1, 2, 3 in Diffuse Large B-Cell Lymphomas, Peripheral T-Cell Lymphomas, and NK/T-Cell Lymphomas
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Min SK, Koh YH, Park Y, Kim HJ, Seo J, Park HR, Cho SJ, Kim IS
- KMID: 2011982
- Korean J Pathol.
- 2012 Apr;46(2):142-150.
BACKGROUND: It has generally been proven that histone acetylation and deacetylation are involved in the malignant transformation. To date, however, this has rarely been studied in cases of malignant lymphoma. METHODS:... -
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- Identifying the KAT6B Mutation via Diagnostic Exome Sequencing to Diagnose Say-Barber-Biesecker-Young-Simpson Syndrome in Three Generations of a Family
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Kim YR, Park JB, Lee YJ, Hong MJ, Kim HT, Kim HJ
- KMID: 2389469
- Ann Rehabil Med.
- 2017 Jun;41(3):505-510.
- doi: 10.5535/arm.2017.41.3.505
Diagnostic exome sequencing (DES) is a powerful tool to analyze the pathogenic variants leading to development delay (DD) and intellectual disability (ID). Recently, heterozygous de novo mutation of the histone... -
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