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The Factors Associated with Influenza Vaccination of Adolescents by School Level: Based on the 13th (2017) Korea Youth Risk Behavior Online Survey

Moon DW, Kim JK, Chung YT, Kim HY, Han JA, Kim JW

Background: Adolescents serve as reservoirs for influenza transmission within their communities. This study thus aimed to investigate the factors associated with influenza vaccination among adolescents based on their school level. Methods:...
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The Factors Associated with High-Sensitivity C-Reactive Protein in Postmenopausal Women: Based on Korea National Health and Nutrition Examination Survey 2016–2017

Kim JK, Moon DW, Chung YT, Kim HY, Han JA, Kim JW

Background: Postmenopausal status increases the risk of cardiovascular disease, and C-reactive protein (CRP) constitutes an independent cardiovascular risk factor. This study aimed to investigate the factors associated with increased high-sensitivity...
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Association between Abdominal Obesity and Cardiovascular Risk Factors in Adults with Normal Body Mass Index: Based on the Sixth Korea National Health and Nutrition Examination Survey

Kim HY, Kim JK, Shin GG, Han JA, Kim JW

BACKGROUND: Abdominal obesity predisposes individuals to cardiovascular disease, but the data in adults with normal body mass index (BMI) are relatively rare. This study aimed to evaluate the characteristics of...
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Influence of Family Communication and Family Function to their Body Mass Index among Medical Students

Moon SH, Park Y, Han JA, Shine BK, Ahn BW, Kang SH

BACKGROUND: Association between obesity and family communication was a controversial issue in previous studies. Previous studies were done on adolescents and adults in overall. This study was done to figure...
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Analysis of Gene Expression in Human Dermal Fibroblasts Treated with Senescence-Modulating COX Inhibitors

Han JA, Kim JI

We have previously reported that NS-398, a cyclooxygenase-2 (COX-2)–selective inhibitor, inhibited replicative cellular senescence in human dermal fibroblasts and skin aging in hairless mice. In contrast, celecoxib, another COX-2–selective inhibitor,...
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Estimation of Prognostic Marker Genes by Public Microarray Data in Patients with Ovarian Serous Cystadenocarcinoma

Yang SD, Jang SS, Han JA, Park HS, Kim JI

PURPOSE: Lymphatic invasion (LI) is regarded as a predictor of the aggressiveness of ovarian cancer (OC). However, LI is not always the major determinant of long-term patient survival. To establish...
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Factors affecting screening for diabetic complications in the community: a multilevel analysis

Han JA, Kim SJ, Kim G, Kim EJ, Lee SY

OBJECTIVES: The objective of the present study was to identify the factors that affect screening for diabetic complications by sex in the community. METHODS: This study used individual-level data from the...
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Test-retest reliability of health behavior items in the Community Health Survey in South Korea

Kim SJ, Han JA, Kim YH, Choi BY, Kim SY, Lee HJ, Oh IH, Cho SI, Lee J, Lee SY

OBJECTIVES: Responses to health-related items on the Community Health Survey (CHS) provide evidence that is used to develop community-based health policy. This study aimed to assess the test-retest reliability of...
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Community-Based Risk Communication Survey: Risk Prevention Behaviors in Communities during the H1N1 crisis, 2010

Kim SJ, Han JA, Lee TY, Hwang TY, Kwon KS, Park KS, Lee KJ, Kim MS, Lee SY

Objectives The present study aimed to investigate the prevalence of and factors associated with H1N1 preventive behaviors in a community-based population. Methods A cross-sectional study was conducted in three urban and two rural...
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Analysis of Gene Expression in Cyclooxygenase-2-Overexpressed Human Osteosarcoma Cell Lines

Han JA, Kim JY, Kim JI

Osteosarcoma is the most common primary bone tumor, generally affecting young people. While the etiology of osteosarcoma has been largely unknown, recent studies have suggested that cyclooxygenase-2 (COX-2) plays a...
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Cyclooxygenase-2 inhibitors modulate skin aging in a catalytic activity-independent manner

Lee ME, Kim SR, Lee S, Jung YJ, Choi SS, Kim WJ, Han JA

  • KMID: 1389733
  • Exp Mol Med.
  • 2012 Sep;44(9):536-544.
It has been proposed that the pro-inflammatory catalytic activity of cyclooxygenase-2 (COX-2) plays a key role in the aging process. However, it remains unclear whether the COX-2 activity is a...
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Analysis of Experimental Researches in Korea on the Effects of Aromatherapy to Relieve Pain

Park JS, Park JE, Yang JS, Kwak HW, Han JA

  • KMID: 2305347
  • Korean J Hosp Palliat Care.
  • 2011 Mar;14(1):8-19.
PURPOSE: This study identifies research trends and provides fundamental data related to curative power of aromatherapy to relieve pain in Korea. METHODS: The study analyzed 44 experimental studies on humans that...
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Transient downregulation of protein O-N-acetylglucosaminylation by treatment of high-dose nicotinamide in human cells

Lee HI, Cho HJ, Han JA, Jang SY, Wang KM, Kang HT, Hwang ES

Nicotinamide at millimolar concentrations affects cell survival in various conditions, and is being utilized therapeutically in many human diseases. However, the effect of an acute treatment of nicotinamide at such...
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Cyclooxygenase-2 promotes cell proliferation, migration and invasion in U2OS human osteosarcoma cells

Lee EJ, Choi EM, Kim SR, Park JH, Kim H, Ha KS, Kim YM, Kim SS, Choe M, Kim JI, Han JA

  • KMID: 756069
  • Exp Mol Med.
  • 2007 Aug;39(4):469-476.
Osteosarcoma is the most common primary bone tumor, but the pathogenesis is not well understood. While cyclooxygeanse-2 (COX-2) is known to be closely associated with tumor growth and metastasis in...
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The role of tonicity responsive enhancer sites in the transcriptional regulation of human hsp70-2 in response to hypertonic stress

Heo JI, Lee MS, Kim JH, Lee JS, Kim J, Park JB, Lee JY, Han JA, Kim JI

  • KMID: 1094155
  • Exp Mol Med.
  • 2006 Jun;38(3):295-301.
The inducible 70 kDa heat shock proteins (Hsp70) in mice are encoded by two almost identical genes, hsp70.1 and hsp70.3. Studies have found that only hsp70.1 is induced by hypertonic...
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DNA Microarray Analysis of Gene Expression Profiles in Aging process of Mouse Brain

Lee MS, Heo JI, Kim JB, Park JB, Lee JY, Han JA, Kim JI

  • KMID: 2166191
  • Genomics Inform.
  • 2006 Mar;4(1):23-32.
In order to investigate the molecular basis of the aging process in brain, we have employed high-density oligonucleotide microarrays providing data on 10,108 gene clusters to define transcriptional patterns in...
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beta-Carotene inhibits inflammatory gene expression in lipopolysaccharide-stimulated macro phages by suppressing redox-based NF-kappaB activation

Bai SK, Lee SJ, Na HJ, Ha KS, Han JA, Lee H, Kwon YG, Chung CK, Kim YM

  • KMID: 1093467
  • Exp Mol Med.
  • 2005 Aug;37(4):323-334.
beta-Carotene has shown antioxidant and antiinflammatory activities; however, its molecular mechanism has not been clearly defined. We examined in vitro and in vivo regulatory function of beta-carotene on the production...
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COX-2 inhibits anoikis by activation of the PI-3K/Akt pathway in human bladder cancer cells

Choi EM, Kwak SJ, Kim YM, Ha KS, Kim JI, Lee SW, Han JA

  • KMID: 1056232
  • Exp Mol Med.
  • 2005 Jun;37(3):199-203.
Cyclooxygenase-2 (COX-2) has been reported to be associated with tumor development and progression as well as to protect cells from apoptosis induced by various cellular stresses. Through a tetracycline-regulated COX-2...
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Prostaglandin E2 stimulates angiogenesis by activating the nitric oxide/cGMP pathway in human umbilical vein endothelial cells

Namkoong S, Lee SJ, Kim CK, Kim YM, Chung HT, Lee H, Han JA, Ha KS, Kwon YG, Kim YM

  • KMID: 1116204
  • Exp Mol Med.
  • 2005 Dec;37(6):588-600.
Prostaglandin E2(PGE2), a major product of cyclooxygenase, has been implicated in modulating angiogenesis, vascular function, and inflammatory processes, but the underlying mechanism is not clearly elucidated. We here investigated the...
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Protective Effect of Heat Shock Protein 70 Against Oxidative Stresses in Human Corneal Fibroblasts

Kim YS, Han JA, Cheong TB, Ryu JC, Kim JC

We evaluated DNA protection effect of heat shock protein (HSP) against cytotoxic effects of exogenous nitric oxide (NO) and reactive oxygen intermediate (ROI). Cultured human corneal fibroblasts were divided into...
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