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Characterization of the Alteration of Cell Cycle Parameters Associated with v-Src Overexpression

Kwak SJ, Han JA, Seong YS

  • KMID: 2175240
  • J Korean Cancer Assoc.
  • 1999 Apr;31(2):418-428.
No abstract available.
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A Case of Amniotic Membrane Transplanation for Late Onset Bleb-Related Endophthalmitis

Han JA, Kim JC, Shyn KH

  • KMID: 2336984
  • J Korean Ophthalmol Soc.
  • 2001 Jan;42(1):212-216.
Endophthalmitis is a severe and unfortunate complication after glaucoma filtering surgery which may present months to years after the initial surgical intervention. Amniotic membrane is immunologically inert and has antiadhesive...
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Hydrogen peroxide mediates doxorubicin-induced transglutaminase 2 expression in PC-14 human lung cancer cell line

Han JA, Park SC

  • KMID: 1029936
  • Exp Mol Med.
  • 1999 Jun;31(2):83-88.
Increased expression of Transglutaminases 2 (TGase 2, TGase C) was observed in PC-14 human lung cancer cells in association with doxorubicin resistance and the reduction of the enzyme expression was correlated with...
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Portal Venous Gas after Insertion Umbilical Venous Catheter: A Case Report

Jun MJ, Han JA, Lee YY, Park YM, Bae SH, Park HW

Hepatic portal vein gas has known for a life-threatening radiologic sign associated with various under lying abdominal diseases. In neonates, air in the portal venous system is a rare finding....
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Vitreous Vascular Endothelial Growth Factor Concentration In Various Vitreoretinal Disorders

Han JA, Cho HK

  • KMID: 2125396
  • J Korean Ophthalmol Soc.
  • 2002 Jan;43(1):96-103.
PURPOSE: Vascular endothelial growth factor (VEGF) has been identified as an endothelial cell-specific angiogenic factor of intraocular neovascularization, a pathologic complication of many vitreoretinal disorders. We studied to evaluate clinical...
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Transient downregulation of protein O-N-acetylglucosaminylation by treatment of high-dose nicotinamide in human cells

Lee HI, Cho HJ, Han JA, Jang SY, Wang KM, Kang HT, Hwang ES

Nicotinamide at millimolar concentrations affects cell survival in various conditions, and is being utilized therapeutically in many human diseases. However, the effect of an acute treatment of nicotinamide at such...
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DNA Microarray Analysis of Gene Expression Profiles in Aging process of Mouse Brain

Lee MS, Heo JI, Kim JB, Park JB, Lee JY, Han JA, Kim JI

  • KMID: 2166191
  • Genomics Inform.
  • 2006 Mar;4(1):23-32.
In order to investigate the molecular basis of the aging process in brain, we have employed high-density oligonucleotide microarrays providing data on 10,108 gene clusters to define transcriptional patterns in...
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The Factors Associated with High-Sensitivity C-Reactive Protein in Postmenopausal Women: Based on Korea National Health and Nutrition Examination Survey 2016–2017

Kim JK, Moon DW, Chung YT, Kim HY, Han JA, Kim JW

Background: Postmenopausal status increases the risk of cardiovascular disease, and C-reactive protein (CRP) constitutes an independent cardiovascular risk factor. This study aimed to investigate the factors associated with increased high-sensitivity...
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The Factors Associated with Influenza Vaccination of Adolescents by School Level: Based on the 13th (2017) Korea Youth Risk Behavior Online Survey

Moon DW, Kim JK, Chung YT, Kim HY, Han JA, Kim JW

Background: Adolescents serve as reservoirs for influenza transmission within their communities. This study thus aimed to investigate the factors associated with influenza vaccination among adolescents based on their school level. Methods:...
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Analysis of Gene Expression in Cyclooxygenase-2-Overexpressed Human Osteosarcoma Cell Lines

Han JA, Kim JY, Kim JI

Osteosarcoma is the most common primary bone tumor, generally affecting young people. While the etiology of osteosarcoma has been largely unknown, recent studies have suggested that cyclooxygenase-2 (COX-2) plays a...
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Expression of Vascular Endothelial Growth Factor after Laser Induced Retinal Vein Occlusion in the Rat Eye

Kim YJ, Oh JH, Han JA, Cho HK

  • KMID: 2109301
  • J Korean Ophthalmol Soc.
  • 2002 Mar;43(3):589-598.
PURPOSE: To examine the effects of retinal vein occlusion (RVO) on VEGF expression and the ultrastructural change of the various ocular tissues in the rat. METHODS: Sprauge Dawley rats were grouped...
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Factors affecting screening for diabetic complications in the community: a multilevel analysis

Han JA, Kim SJ, Kim G, Kim EJ, Lee SY

OBJECTIVES: The objective of the present study was to identify the factors that affect screening for diabetic complications by sex in the community. METHODS: This study used individual-level data from the...
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COX-2 inhibits anoikis by activation of the PI-3K/Akt pathway in human bladder cancer cells

Choi EM, Kwak SJ, Kim YM, Ha KS, Kim JI, Lee SW, Han JA

  • KMID: 1056232
  • Exp Mol Med.
  • 2005 Jun;37(3):199-203.
Cyclooxygenase-2 (COX-2) has been reported to be associated with tumor development and progression as well as to protect cells from apoptosis induced by various cellular stresses. Through a tetracycline-regulated COX-2...
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Influence of Family Communication and Family Function to their Body Mass Index among Medical Students

Moon SH, Park Y, Han JA, Shine BK, Ahn BW, Kang SH

BACKGROUND: Association between obesity and family communication was a controversial issue in previous studies. Previous studies were done on adolescents and adults in overall. This study was done to figure...
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Ultrastructural Changes of Corneal Edema in Endotoxin-induced Uveitis Model

Han JA, Kwak IH, Kim JC

  • KMID: 2108778
  • J Korean Ophthalmol Soc.
  • 1999 Aug;40(8):2103-2110.
It has been well known that Nitrogen Oxide (NO)plays an important role in endotoxin-induced uveitis (EIU)model,but there has been few researches on development of corneal toxicity in this model. This...
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Analysis of Gene Expression in Human Dermal Fibroblasts Treated with Senescence-Modulating COX Inhibitors

Han JA, Kim JI

We have previously reported that NS-398, a cyclooxygenase-2 (COX-2)–selective inhibitor, inhibited replicative cellular senescence in human dermal fibroblasts and skin aging in hairless mice. In contrast, celecoxib, another COX-2–selective inhibitor,...
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Cyclooxygenase-2 promotes cell proliferation, migration and invasion in U2OS human osteosarcoma cells

Lee EJ, Choi EM, Kim SR, Park JH, Kim H, Ha KS, Kim YM, Kim SS, Choe M, Kim JI, Han JA

  • KMID: 756069
  • Exp Mol Med.
  • 2007 Aug;39(4):469-476.
Osteosarcoma is the most common primary bone tumor, but the pathogenesis is not well understood. While cyclooxygeanse-2 (COX-2) is known to be closely associated with tumor growth and metastasis in...
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Cyclooxygenase-2 inhibitors modulate skin aging in a catalytic activity-independent manner

Lee ME, Kim SR, Lee S, Jung YJ, Choi SS, Kim WJ, Han JA

  • KMID: 1389733
  • Exp Mol Med.
  • 2012 Sep;44(9):536-544.
It has been proposed that the pro-inflammatory catalytic activity of cyclooxygenase-2 (COX-2) plays a key role in the aging process. However, it remains unclear whether the COX-2 activity is a...
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Association between Abdominal Obesity and Cardiovascular Risk Factors in Adults with Normal Body Mass Index: Based on the Sixth Korea National Health and Nutrition Examination Survey

Kim HY, Kim JK, Shin GG, Han JA, Kim JW

BACKGROUND: Abdominal obesity predisposes individuals to cardiovascular disease, but the data in adults with normal body mass index (BMI) are relatively rare. This study aimed to evaluate the characteristics of...
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Estimation of Prognostic Marker Genes by Public Microarray Data in Patients with Ovarian Serous Cystadenocarcinoma

Yang SD, Jang SS, Han JA, Park HS, Kim JI

PURPOSE: Lymphatic invasion (LI) is regarded as a predictor of the aggressiveness of ovarian cancer (OC). However, LI is not always the major determinant of long-term patient survival. To establish...
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