- Immunohistochemical Localization of Guanine Aminohydrolase, a Protein Identical with Novel Protein p51-nedasin, and SAP 102 in the Rat Retina
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Kim YH, Lee HY
- KMID: 2030745
- Korean J Anat.
- 2002 Apr;35(2):99-104.
Guanine aminohydrolase (GAH), one of purine metabolizing enzymes rich in the nervous system was proved to have identical amino acid sequence to a recently identified novel protein p51-nedasin, NE-dlg/SAP102-associated protein.... -
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- Localization of Guanine Aminohydrolase in the Postnatl Developing Rat Retina
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Lee HY
- KMID: 1558432
- Korean J Anat.
- 2001 Apr;34(2):161-167.
Guanine aminohydrolase (GAH; Guanine deaminase, EC 3.5.4.3) is an enzyme that has a role in purine catabolism. Most of the enzymes involved in purine catabolism have been studied for their... -
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- Purification and Characterization of Guanine Aminohydrolase from Rat Cerebrum
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Cha HJ, Jung HW, Koh YC, Sim BS, Park JB, Kim SW
- KMID: 1953539
- J Korean Neurosurg Soc.
- 1984 Dec;13(4):611-625.
Guanine aminohydrolase(GAH;EC 3. 5. 4. 3.) was partially purified 122-fold from rat cerebrum to a specific activity of 7.22 in its per mg protein with a recovery of 7.47% by... -
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- Lamivudine: fading into the mists of time
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Choi J, Lim YS
- KMID: 2406039
- Clin Mol Hepatol.
- 2017 Dec;23(4):314-315.
- doi: 10.3350/cmh.2017.0110
No abstract available. -
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- Antiviral Effect of Entecavir Switching Therapy in Chronic Hepatitis B Patients with Clevudine-associated Myopathy
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Tak WY
- KMID: 1775779
- Korean J Gastroenterol.
- 2013 Jan;61(1):1-2.
- doi: 10.4166/kjg.2013.61.1.1
No abstract available. -
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- Comparative Effectiveness of Lamivudine versus Entecavir in Patients with Hepatocellular Carcinoma: Watch out for Confounders!
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Kim HY
- KMID: 2412089
- Gut Liver.
- 2016 Nov;10(6):869-870.
- doi: 10.5009/gnl16476
No abstract available. -
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- A Mitochondrial Mutation in Leber's Hereditary Optic Neuropathy
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Hwang JM, Park HW
- KMID: 2205183
- J Korean Ophthalmol Soc.
- 1995 Dec;36(12):2218-2224.
Leber's hereditary optic neuropathy is caused by a single nucleotide change in the mitochondrial deoxynucleic acid(mtDNA). We identified a single guanine to adenine transition mutation in the mitochondrial DNA at... -
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- SLC26A4 Mutations in Korean Population
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Kim BG
- KMID: 1963750
- Korean J Otorhinolaryngol-Head Neck Surg.
- 2014 Nov;57(11):733-737.
- doi: 10.3342/kjorl-hns.2014.57.11.733
SLC26A4 mutations are common cause of congenital hearing loss in East Asia. The carrier frequency of SLC26A4 mutations is 1 in 75 in Korean populations. The SLC26A4 mutation spectrum varies... -
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- System-Wide Expression and Function of Olfactory Receptors in Mammals
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Oh SJ
- KMID: 2413245
- Genomics Inform.
- 2018 Mar;16(1):2-9.
- doi: 10.5808/GI.2018.16.1.2
Olfactory receptors (ORs) in mammals are generally considered to function as chemosensors in the olfactory organs of animals. They are membrane proteins that traverse the cytoplasmic membrane seven times and... -
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- A Case of Leber's Hereditary Optic Nouropathy Showing 11778 Point Mutation of Mitochondrial DNA
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Jung YS, Park SK, Lee SY, Hah JS, Park MY, Lee SJ, Lee J
- KMID: 1969409
- Yeungnam Univ J Med.
- 1999 Jun;16(1):114-118.
- doi: 10.12701/yujm.1999.16.1.114
Leber's hereditary optic neuropathy(LHON) is an optic nerve disease that causes blindness and is associated with maternally inherited mitochondrial DNA(mt DNA) mutations. The most common mitochondrial DNA mutation among LHON... -
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- Two Cases of Generalized Pustular Psoriasis Improved with Combination Treatment of Mycophenolate Mofetil
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Jang YH, Lee WC, Na GY, Lee SJ, Kim DW
- KMID: 1977859
- Korean J Dermatol.
- 2003 Dec;41(12):1644-1649.
Mycophenolate mofetil(MMF) is a new immunosuppressant which non-competitively and reversibly blocks the de novo synthesis of guanine nucleotides required for DNA and RNA synthesis during lymphocyte proliferation. So MMF selectively... -
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- R1467H Variants of Rho Guanine Nucleotide Exchange Factor 11 (ARHGEF11) are Associated with Type 2 Diabetes Mellitus in Koreans
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Jin QS, Kim SH, Piao SJ, Lim HA, Lee SY, Hong SB, Kim YS, Lee HJ, Nam M
- KMID: 2222364
- Korean Diabetes J.
- 2010 Dec;34(6):368-373.
- doi: 10.4093/kdj.2010.34.6.368
BACKGROUND: The human Rho guanine nucleotide exchange factor 11 (ARHGEF11) functions as an activator of Rho GTPases and is thought to influence insulin signaling. The R1467H variant of ARHGEF11 has... -
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- MELAS Syndrome Confirmed by Mitochondrial DNA Analysis in Siblings
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Rah YG, Chae SA, Lim IS, Lee DK, Yoo BH, Ko TS, Yoo HW
- KMID: 1946343
- J Korean Pediatr Soc.
- 1999 Mar;42(3):412-418.
MELAS(mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes) syndrome is a major subgroup of mitochondrial myopathy. Recent advances in molecular genetics revealed specific mutations in mitochondrial DNA which cause MELAS.... -
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- A Case of Infantile Alexander Disease
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Park GM, Ko JH, Min KS
- KMID: 2329431
- J Korean Child Neurol Soc.
- 2009 Nov;17(2):215-220.
Alexander disease(AD) is a rare fatal demyelinating disorder, caused by the mutation of glial fibrillary acidic protein(GFAP) gene. It is characterized by progressive demyelination of central nervous system, and the... -
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- Mineral trioxied aggregate and its substitutes
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Cho YB
- KMID: 2294340
- J Korean Acad Conserv Dent.
- 2010 May;35(3):149-151.
- doi: 10.5395/JKACD.2010.35.3.149
Since its introduction in 1993, Mineral Trioxide Aggregate (MTA) has been shown to be superior to others in sealing, biocompatibility, and many other aspects of clinical endodontics. MTA is primarily... -
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- Conserved Roles of MonA in Fungal Growth and Development in Aspergillus Species
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Son YE, Park HS
- KMID: 2470178
- Mycobiology.
- 2019 Dec;47(4):457-465.
- doi: 10.1080/12298093.2019.1677380
MonA is a subunit of a guanine nucleotide exchange factor that is important for vacuole passing and autophagy processes in eukaryotes. In this study, we characterized the function of MonA,... -
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- Expression of Guanine Deaminase in the Developing Rat Brain
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Lee KH, Choi JS, Lee HY, Shin DH, Kang TC, Kim HJ, Cho SS, Baik SH, Seong YS, Park JB
- KMID: 2224585
- Korean J Anat.
- 1999 Apr;32(2):245-252.
Guanine aminohydrolase (GAH; Guanine deaminase, EC 3.5.4.3) is an enzyme that has a role in purine catabolism. This enzyme produces xanthine and ammonia by hydrolysis of guanine, and xanthine is... -
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- Failure of orthograde MTA filling: MTA wash-out?
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Kim Y, Lee CY, Kim E, Jung IY
- KMID: 2176607
- J Korean Acad Conserv Dent.
- 2011 Nov;36(6):510-514.
- doi: 10.5395/JKACD.2011.36.6.510
Mineral trioxide aggregate (MTA), which was originally developed for repair of root perforations, is a biocompatible material with numerous clinical applications in endodontics. MTA must be allowed to set in... -
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- Aberrant CpG Islands Hypermethylation Profiles in Malignant Gliomas
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Kim KR, Kim E, Son EI
- KMID: 1734665
- Brain Tumor Res Treat.
- 2014 Apr;2(1):29-35.
- doi: 10.14791/btrt.2014.2.1.29
BACKGROUND: The authors analyzed whether the promoter hypermethylation of cancer-related genes was involved in the tumorigenesis of malignant gliomas. METHODS: A total of 29 patients received surgery and histologically confirmed to... -
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- Mon1 Is Essential for Fungal Virulence and Stress Survival in Cryptococcus neoformans
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Son YE, Jung WH, Oh SH, Kwak JH, Cardenas M, Park HS
- KMID: 2428809
- Mycobiology.
- 2018 Jun;46(2):114-121.
- doi: 10.1080/12298093.2018.1468053
Mon1 is a guanine nucleotide exchange factor subunit that activates the Ypt7 Rab GTPase and is essential for vacuole trafficking and autophagy in eukaryotic organisms. Here, we identified and characterized... -
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