- Treatment Strategy of Growth Hormone Secreting Pituitary Adenoma
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Lew GU, Ha Y, Kim SH
- KMID: 1955475
- J Korean Neurosurg Soc.
- 1998 Dec;27(12):1682-1686.
The goals of the pituitary tumor surgery are restoration of the normal pituitary function and relieving the mass effect on the adjacent normal brain structures. The main purpose of this... -
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- Ectopic Growth Hormone-Secreting Pituitary Adenoma of the Clivus
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Choi JH, Park MK, Choi SS, Kim KU
- KMID: 2189075
- J Korean Neurosurg Soc.
- 2006 Apr;39(4):306-309.
Ectopic pituitary adenoma, occurring outside the sella turcica without any continuity with intrasellar pituitary gland is very rare. So far, less than 90 such cases have been reported in the... -
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- Endocrine Outcome of Endoscopic Endonasal Transsphenoidal Surgery in Functioning Pituitary Adenomas
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Choe JH, Lee KS, Jeun SS, Cho JH, Hong YK
- KMID: 2067345
- J Korean Neurosurg Soc.
- 2008 Sep;44(3):151-155.
- doi: 10.3340/jkns.2008.44.3.151
OBJECTIVE: Microscopic and endoscopic transsphenoidal approach (TSA) are major surgical techniques in the treatment of pituitary adenoma. Endoscopic endonasal transsphenoidal approach (EETSA) has been increasingly used for pituitary adenomas, however,... -
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- A Case of Secondary Amenorrhea Associated with Pituitary Tumor
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Nam YS, Lee SH, Kwak IP, Yoon TK, Cha KY
- KMID: 2269585
- Korean J Obstet Gynecol.
- 1998 Jun;41(6):1734-1737.
Secondary amenorrhea is usually defined as the absence of menses for at least 6 months in a woman who previously had been having regular menses, or the absence of menses... -
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- Gigantism caused by growth hormone secreting pituitary adenoma
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Rhee N, Jeong K, Yang EM, Kim CJ
- KMID: 1803861
- Ann Pediatr Endocrinol Metab.
- 2014 Jun;19(2):96-99.
- doi: 10.6065/apem.2014.19.2.96
Gigantism indicates excessive secretion of growth hormones (GH) during childhood when open epiphyseal growth plates allow for excessive linear growth. Case one involved a 14.7-year-old boy presented with extreme tall... -
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- Surgical Results of Growth Hormone-Secreting Pituitary Adenoma
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Kim MS, Jang HD, Kim OL
- KMID: 1495115
- J Korean Neurosurg Soc.
- 2009 May;45(5):271-274.
- doi: 10.3340/jkns.2009.45.5.271
OBJECTIVE: We retrospectively analyzed the surgical outcomes of 42 patients with growth hormone (GH)-secreting pituitary adenoma to evaluate the clinical manifestations and to determine which preoperative factors that significantly influence... -
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- Gamma Knife Radiosurgery for Growth Hormone-secreting Pituitary Adenoma following Trans-sphenoidal Approach
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Jun JK, Lim YJ, Koh JS, Rhee BA, Kim GK, Kim TS
- KMID: 1588436
- J Korean Neurosurg Soc.
- 2004 Oct;36(4):275-280.
OBJECTIVE: The results of gamma knife radiosurgery(GKRS) for growth hormone(GH)-secreting pituitary adenoma are investigated to identify the role of adjuvant GKRS for remnant or recurrent tumor following transsphenoidal approach(TSA). METHODS:... -
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- Growth Hormone-Secreting Pituitary Adenoma: Clinical and MR Imaging Findings
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Park HS, Chang KH, Han MH, Sim JS, Lee SH, Song JU, Yoo IK, Jung HW, Yeon KM
- KMID: 2346816
- J Korean Radiol Soc.
- 1996 Oct;35(4):441-446.
PURPOSE: To describe clinical and MRI findings of growth hormone-secreting pituitary adenoma, to determine ifthere are any characteristic MRI findings different from those of other pituitary adenomas, to evaluate the... -
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- Multiple Myeloma in a Patient with Acromegaly
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Kang YM, Choi JH, Lee MJ, Ahn A, Park CJ, Chang K, Seo S, Hong SI, Kim MS
- KMID: 2407113
- Endocrinol Metab.
- 2015 Mar;30(1):110-115.
- doi: 10.3803/EnM.2015.30.1.110
Acromegaly is a slowly progressing condition resulting from excess growth hormone (GH), generally caused by a GH-secreting pituitary adenoma. Cancer is the third most common cause of mortality in patients... -
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- Treatment Outcome of Gamma Knife Radiosurgery for GH-Secreting Pituitary Tumors
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Lim YJ, Choi YH, Leem W, Lee KT, Koh JS, Kim TS, Kim GK, Rhee BA
- KMID: 1904690
- J Korean Neurosurg Soc.
- 2001 May;30(5):567-574.
OBJECTIVE: As for growth hormone(GH) secreting pituitary adenoma, it's remission should be declared on the basis of satisfactory controlling of the tumor, normalization of hormonal level, and symptomatic improvement of... -
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- Expression of TRH Receptor Gene in GH-Secreting Piruitary Adenomas
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Yang IM, Park SJ, Ryu JW, Chung JH, Ryu MS, Woo JT, Kim SW, Kim JW, Kim YS, Choi YK
- KMID: 1999280
- J Korean Soc Endocrinol.
- 1997 Sep;12(3):349-356.
Background: To test the hypothesis that Galphas gene mutation may suppress the expression of TRH-R gene, we investigated whether hTRH-R gene expression is lower in human GH-secreting pituitary adenomas with... -
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- Correlation between serum prolactin levels and immunocytochemical findings of pituitary adenomas in patients with acromegaly
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Kang BH, Jeong IK, Cho DS, Kang HW, Kim HH, Kim BJ, Min TH, Son JS, Hong SN, Lee CY, Lee BW, Noh JH, Chung JH, Min YK, Lee MS, Lee MK, Kim KW, Suh YL
- KMID: 2306071
- Korean J Med.
- 2003 Feb;64(2):197-203.
BACKGROUND: Acromegaly occurs by excessive secretion of growth hormone and more than 99% of cases are caused by a growth hormone-secreting pituitary adenoma. Pituitary adenomas expressing multiple immunoreactivities are common.... -
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- A case of two consecutive deliveries in a woman with acromegaly
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Choi H, Lee Y, Chung IH, Koh JH, Kim MJ, Shin YG, Chung CH
- KMID: 2252525
- Korean J Med.
- 2004 Dec;67(6):662-666.
Acromegaly is a rare pituitary disorder and usually results from GH hypersecretion by a somatotroph adenoma. Disturbed pituitary function might lead to infertility or early pregnancy termination. Pregnancy in acromegaly... -
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- Therapeutic Effect of a Novel Chimeric Molecule Targeting Both Somatostatin and Dopamine Receptors on Growth Hormone-Secreting Pituitary Adenomas
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Kim J, Oh JH, Harlem H, Culler MD, Ku CR, Lee EJ
- KMID: 2471734
- Endocrinol Metab.
- 2020 Mar;35(1):177-187.
- doi: 10.3803/EnM.2020.35.1.177
BACKGROUND: Acromegaly is a rare disease primarily caused by growth hormone (GH)-secreting pituitary adenomas, and its treatment is costly. Moreover, some patients are unresponsive to treatment. Hence, there are increasing... -
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- Characteristics of gsp-Positive Growth Hormone-secreting Pituitary Tumors
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Park BJ, Kim GK, Lim YJ, Kim TS, Rhee BA, Leem W, Yang IM, Choi YK
- KMID: 2339587
- J Korean Neurosurg Soc.
- 1997 Aug;26(8):1059-1064.
A subset of human growth hormone(GH)-secreting pituitary tumors contains the gsp oncogene that encodes an activation mutation of the alpha subunit of Gsalpha, a stimulatory GTP-binding protein. The purpose of... -
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- A Case of Isolated Familial Somatotropinoma
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Park HR, Kim EA, Jiang MH, Jang CS, Lee KW, Hong SB, Kim EY, Lim MK, Nam MS, Kim YS
- KMID: 2200527
- J Korean Soc Endocrinol.
- 2004 Aug;19(4):398-405.
The familial occurrence of a pituitary adenoma associated with multiple endocrine neoplasia (MEN) type 1 or Carney complex is a well-recognized entity. However, an isolated familial somatotropinoma is a rare... -
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- Outcome of Surgery and Radiotherapy in Acromegaly
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Shin CS, Yim CH, Jung HW, Han DH, Park DJ, Kim HJ, Lee YY, Park KS, Kim IH, Kim SY, Lee HG
- KMID: 2142202
- J Korean Soc Endocrinol.
- 1998 Jun;13(2):156-166.
BACKGROUND: The primary goal of therapy for acmmegaly is to reduce excess growth hormone (GH) secretion through surgical excision of pituitary adenoma and, in patients with large tumors, to debulk... -
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- Acromegaly with Diabetes Insipidus after Pituitary Tumor Removal: Successful Pregnancy and Delivery
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Kim SH, Kim JI, Park YM, Won IS, Shin KC, Jo Y, Lee S, Kim YS, Lee KY, Park IB
- KMID: 2177862
- J Korean Endocr Soc.
- 2010 Mar;25(1):56-60.
- doi: 10.3803/jkes.2010.25.1.56
A 33-year-old woman visited our hospital because of oligomenorrhea. Acromegaly was diagnosed based on elevated insulin like growth factor-I (IGF-I) and paradoxical growth hormone (GH) rise in oral glucose tolerance... -
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- Using Growth Hormone Levels to Detect Macroadenoma in Patients with Acromegaly
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Park JY, Kim JH, Kim SW, Chung JH, Min YK, Lee MS, Lee MK, Kim KW
- KMID: 2384241
- Endocrinol Metab.
- 2014 Dec;29(4):450-456.
- doi: 10.3803/EnM.2014.29.4.450
BACKGROUND: The aim of this study was to assess the clinical differences between acromegalic patients with microadenoma and patients with macroadenoma, and to evaluate the predictive value of growth hormone... -
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- Gene Expression of Somatostatin Receptor (Subtype 2 & 5), Gi2 alpha and Pit-1 in GH-secreting Pituitary Adenomas
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Ryu MS, Yang IM, Park CY, Woo JT, Kim SW, Kim JW, Kim YS, Choi YK, Kim EH, Park SJ, Kim KG
- KMID: 2199901
- J Korean Soc Endocrinol.
- 2002 Apr;17(2):158-169.
BACKGROUND: Mutation of Gs protein subunit (gsp oncogene), detected in about 30~40% of growth hormone (GH)-secreting pituitary tumors, is associated with an increased long-acting somatostatin analog octreotide sensitivity. However, the... -
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