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11β-Hydroxysteroid Dehydrogenase Type 1 Inhibition Attenuates the Adverse Effects of Glucocorticoids on Dermal Papilla Cells

Lee SE, Lee EY, Kang SJ, Lee SH

PURPOSE: Glucocorticoids, stress-related hormones, inhibit hair growth. Intracellular glucocorticoid availability is regulated by 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1). 11β-HSD1 was recently detected in keratinocytes and fibroblasts. However, the expression of...
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Improvement of pregnancy rate by intrauterine administration of dexamethasone and recombinant human leukemia inhibitory factor at the time of embryo transfer in cattle

Roh S, Kim SW, Jung YG, Park JI

Bovine embryos (day 5) were cultured to day 10 with or without 100 ng/mL PGF2α in medium supplemented with control; 100 nM Dex; 1,000 U/mL recombinant human leukemia inhibitory factor...
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Comparison of the Effect of Vitamin K2 and Risedronate on Trabecular Bone in Glucocorticoid-Treated Rats: A Bone Histomorphometry Study

Iwamoto J, Matsumoto , Tadeda T, Sato Y, Yeh JK

  • KMID: 2396058
  • Yonsei Med J.
  • 2009 Apr;50(2):189-194.
PURPOSE: To compare the effect of vitamin K2 and risedronate on trabecular bone in glucocorticoid (GC)-treated rats. MATERIALS AND METHODS: Forty-eight Sprague-Dawley female rats, 3 months of age, were randomized...
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Expression of glucocorticoid receptor mRNAs in glucocorticoid-resistant nasal polyps

Choi BR, Kwon JH, Gong SJ, Kwon MS, Cho JH, Kim JH, Oh S, Roh HJ, Kim DE

  • KMID: 1098080
  • Exp Mol Med.
  • 2006 Oct;38(5):466-473.
Glucocorticoids (GCs) are the most effective group of medications available to treat inflammation. Although most patients with inflammation respond to GC, a small group of patients exhibit persistent GC-resistance with...
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In vivo ligation of glucocorticoid-induced TNF receptor enhances the T-cell immunity to herpes simplex virus type 1

La S, Kim E, Kwon B

  • KMID: 1056231
  • Exp Mol Med.
  • 2005 Jun;37(3):193-198.
GITR (glucocorticoid-induced TNF receptor) is a recently identified member of the TNF receptor superfamily. The receptor is preferentially expressed on CD4+CD25+ regulatory T cells and GITR signals break the suppressive...
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Prevention of chronic graft-versus-host disease by stimulation with glucocorticoid-induced TNF receptor

Kim J, Choi WS, Kim HJ, Kwon B

  • KMID: 1105281
  • Exp Mol Med.
  • 2006 Feb;38(1):94-99.
GITR (glucocorticoid-induced TNF receptor) is a recently identified member of the TNF receptor superfamily. The receptor is preferentially expressed on CD4+CD25+ regulatory T cells and GITR signals break the suppressive...
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The Steroid Effect on the Blood-Ocular Barrier Change Induced by Triolein Emulsion as seen on Contrast-Enhanced MR Images

Lee JY, Eun CK, Kim YW, Kim HJ, Jung YJ, Jae SY, Cho BM, Choi SH

OBJECTIVE: The purpose of this study is to evaluate the effect of dexamethasone on the damaged blood-ocular barrier caused by triolein emulsion, using contrast-enhanced MR imaging. MATERIALS AND METHODS: An...
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