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The Ethanol Extract of Croton Seed Inhibits the Oral Pathogen, Streptococcus mutans

Kim JH, Jung SS, Kang CH, You YO, Kim KJ

It is noted that Streptococcus mutans (S. mutans) triggers dental caries establishment by two major factors: the synthesis of organic acids, which demineralize dental enamel, and the synthesis of glucans,...
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Agrobacterium sp.-derived β-1,3-glucan enhances natural killer cell activity in healthy adults: a randomized, double-blind, placebo-controlled, parallel-group study

Lee YJ, Paik DJ, Kwon DY, Yang HJ, Park Y

BACKGROUND/OBJECTIVES: The present study investigated the hypothesis that a highly pure linear β-1,3-glucan produced by Agrobacterium sp. R259 enhances human natural killer (NK) cell activity and suppresses pro-inflammatory cytokines. SUBJECTS/METHODS: In...
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Determination of Glucan Contents in the Fruiting Bodies and Mycelia of Lentinula edodes Cultivars

Bak WC, Park JH, Park YA, Ka KH

Shiitake mushrooms (Lentinula edodes) containing beta-glucans may be beneficial for human health; they have been used in the treatment of cancer, hypertension, and high cholesterol levels. The objective of this...
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Benefits of a Continuous Ambulatory Peritoneal Dialysis (CAPD) Technique with One Icodextrin-Containing and Two Biocompatible Glucose-Containing Dialysates for Preservation of Residual Renal Function and Biocompatibility in Incident CAPD Patients

Yoon HE, Chang YK, Shin SJ, Choi BS, Kim BS, Park CW, Song HC, Yoon SA, Jin DC, Kim YS

In a prospective randomized controlled study, the efficacy and safety of a continuous ambulatory peritoneal dialysis (CAPD) technique has been evaluated using one icodextrin-containing and two glucose-containing dialysates a day....
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Outdoor (1-->3)-beta-D-glucan Levels and Related Climatic Factors

Hwang SH, Yoon CS, Park JB

  • KMID: 1791977
  • J Prev Med Public Health.
  • 2014 Mar;47(2):124-128.
OBJECTIVES: To evaluate the monthly variation in the airborne (1-->3)-beta-D-glucan level throughout one year and its relationship with climatic factors (temperature, relative humidity, wind speed, hours of daylight, cloud cover,...
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Evaluation of the Protective Effect of Beta Glucan on Amikacin Ototoxicity Using Distortion Product Otoacoustic Emission Measurements in Rats

Bayindir T, Filiz A, Iraz M, Kaya S, Tan M, Kalcioglu

  • KMID: 2278513
  • Clin Exp Otorhinolaryngol.
  • 2013 Mar;6(1):1-6.
OBJECTIVES: This experimental study investigated the possible protective effect of beta glucans on amikacin ototoxicity. METHODS: Thirty-eight rats with normal distortion product otoacoustic emissions (DPOAEs) were divided into four groups. Group...
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Immunomodulatory effect of beta-glucan derived from Saccharomyces cerevisiae strains

Lee YO, Shin MS, Lee WK

  • KMID: 2055092
  • J Biomed Res.
  • 2013 Mar;14(1):23-27.
The aim of this study was to evaluate immunopotentiating activities of beta-glucan derived from Saccharomyces (S.) cerevisiae and to select new strains having possibility as an immune-enhancing substance. We examined...
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Binding Specificity of Philyra pisum Lectin to Pathogen-Associated Molecular Patterns, and Its Secondary Structure

Park BT, Kim BS, Park H, Jeong J, Hyun H, Hwang HS, Kim HH

We recently reported a Philyra pisum lectin (PPL) that exerts mitogenic effects on human lymphocytes, and its molecular characterization. The present study provides a more detailed characterization of PPL based...
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The public dialogue and conflict resolution skills of Korean physicians

Ahn D

The recent conflict between the organization of medical professionals and the government agencies regarding health policy exemplified the incapability of doctors to resolve social conflicts. Doctors have shown strong dissent...
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Are You Being Rejected or Excluded? Insights from Neuroimaging Studies Using Different Rejection Paradigms

Premkumar

Rejection sensitivity is the heightened tendency to perceive or anxiously expect disengagement from others during social interaction. There has been a recent wave of neuroimaging studies of rejection. The aim...
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Hypoglycemic and Hypocholesterolemic Effects of Botryosphaeran from Botryosphaeria rhodina MAMB-05 in Diabetes-Induced and Hyperlipidemia Conditions in Rats

Miranda-Nantes CCBO, Fonseca EA, Zaia CT, Dekker RF, Khaper N, Castro IA, Barbosa AM

  • KMID: 2312640
  • Mycobiology.
  • 2011 Sep;39(3):187-193.
Botryosphaeran, a water-soluble exopolysaccharide of the beta-(1 --> 3;1 --> 6)-D-glucan type that has been isolated from the culture medium of Botryosphaeria rhodina MAMB-05 grown in submerged fermentation using glucose...
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Stimulatory Effect of beta-glucans on Immune Cells

Kim HS, Hong JT, Kim Y, Han SB

beta-Glucans are naturally occurring polysaccharides that are produced by bacteria, yeast, fungi, and many plants. Although their pharmacological activities, such as immunomodulatory, anti-infective and anti-cancer effects, have been well studied,...
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Maturation of bone marrow-derived dendritic cells by a novel beta-glucan purified from Paenibacillus polymyxa JB115

Ko EJ, Byon YY, Jee Y, Shin T, Park SC, Hahn TW, Joo HG

We investigated the immunostimulatory effects of a novel beta-glucan purified from Paenibacillus (P.) polymyxa JB115 on bone marrow-derived dendritic cells (DCs), a type of potent antigen-presenting cells. beta-glucan isolated from...
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High Peritoneal Transport Status is Not an Independent Risk Factor for High Mortality in Patients Treated with Automated Peritoneal Dialysis

Chang TI, Park JT, Lee DH, Lee JH, Yoo TH, Kim BS, Kang SW, Lee HY, Choi KH

We undertook this study to elucidate whether baseline peritoneal membrane transport characteristics are associated with high mortality in incident automated peritoneal dialysis (APD) patients. This retrospective study includes 117 patients...
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Potentiation of Innate Immunity by beta-Glucans

Seong SK, Kim HW

  • KMID: 2312582
  • Mycobiology.
  • 2010 Jun;38(2):144-148.
beta-Glucans have been known to exhibit antitumor activities by potentiating host immunity by an unknown mechanism. The C-type lectin dectin-1, a beta-glucan receptor, is found on the macrophage and can...
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Deletion of GBG1/AYR1 Alters Cell Wall Biogenesis in Saccharomyces cerevisiae

Ahn KW, Kim SW, Kang HG, Kim KH, Park YH, Choi WJ, Park HM

  • KMID: 2312574
  • Mycobiology.
  • 2010 Jun;38(2):102-107.
We identified a gene for beta-1,3-glucan synthesis (GBG1), a nonessential gene whose disruption alters cell wall synthesis enzyme activities and cell wall composition. This gene was cloned by functional complementation...
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Dendritic Cell Activation by Glucan Isolated from Umbilicaria Esculenta

Kim HS, Kim JY, Lee HK, Kim MS, Lee SR, Kang JS, Kim HM, Lee KA, Hong JT, Kim Y, Han SB

BACKGROUND: Lichen-derived glucans have been known to stimulate the functions of immune cells. However, immunostimulatory activity of glucan obtained from edible lichen, Umbilicaria esculenta, has not been reported. Thus we...
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Comparison of Icodextrin and 2.5% Glucose in Potassium Metabolism by Acute K+oad via Dialysate in Continuous Ambulatory Peritoneal Dialysis Patients

Yi JH, Yun YW, Han SW, Kim HJ

This study aimed to compare the increment in plasma potassium concentration ([K+]) as well as the role of internal K+ balance for its changes following acute K+ supplementation between conventional...
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A novel beta-glucan produced by Paenibacillus polymyxa JB115 induces nitric oxide production in RAW264.7 macrophages

Chang ZQ, Lee JS, Hwang MH, Hong JH, Jung HK, Lee SP, Park SC

The effect of extracellular beta-(1-->3), (1-->6)-glucan, produced by Paenibacillus polymyxa JB115, on nitric oxide (NO) production in RAW264.7 macrophages was investigated. beta-glucan induced the production of NO by RAW264.7 macrophages...
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Severe hypoglycemia due to falsely elevated capillary blood glucose levels in a peritoneal dialysis patient using icodextrin: A case report

Cho EJ, Lee SH

In a patient with diabetes mellitus undergoing continuous ambulatory peritoneal dialysis with icodextrin, icodextrin is partially absorbed via lymphatics into the systemic circulation and its metabolites may affect the enzymatic...
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