- Methionyl-tRNA Synthetase is a Useful Diagnostic Marker for Lymph Node Metastasis in Non-Small Cell Lung Cancer
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Lee JM, Kim T, Kim EY, Kim A, Lee DK, Kwon NH, Kim S, Chang YS
- KMID: 2460216
- Yonsei Med J.
- 2019 Nov;60(11):1005-1012.
- doi: 10.3349/ymj.2019.60.11.1005
PURPOSE: Identification of lymph node (LN) metastasis in non-small cell lung cancer (NSCLC) is critical for disease staging and selection of therapeutic modalities. Sometimes it is not possible to obtain... -
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- Virus-like Particle Vaccine Containing Toxoplasma gondii Rhoptry Protein 13 Induces Protection against T. gondii ME49 Infection in Mice
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Kang HJ, Chu KB, Lee SH, Kim MJ, Park H, Jin H, Quan FS
- KMID: 2463745
- Korean J Parasitol.
- 2019 Oct;57(5):543-547.
- doi: 10.3347/kjp.2019.57.5.543
Toxoplasma gondii can infect humans worldwide, causing serious diseases in pregnant women and immunocompromised individuals. T. gondii rhoptry protein 13 (ROP13) is known as one of the key proteins involved... -
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- Role of immunoreactive patterns of lymph nodes in neck dissection cases of oral squamous cell carcinoma: a clinical and histopathological study
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Bhatlawande HC, Kale AD, Desai KM, Hallikerimath S, Belaldavar C, Mane D, Angadi PV, M M, Muttagi S
- KMID: 2461479
- J Korean Assoc Oral Maxillofac Surg.
- 2019 Oct;45(5):267-275.
- doi: 10.5125/jkaoms.2019.45.5.267
OBJECTIVES: Metastasis in oral squamous cell carcinoma (OSCC) can occur in a variety of ways, and draining lymphatics and lymph nodes serve as a common route. Prior to metastasis, lymph... -
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- Curcumin Elevates T(FH) Cells and Germinal Center B Cell Response for Antibody Production in Mice
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Kim DH, Lee HG, Choi JM
- KMID: 2461199
- Immune Netw.
- 2019 Oct;19(5):e35.
- doi: 10.4110/in.2019.19.e35
Curcumin is a natural product extracted from Curcuma longa. It has been reported as a potent antioxidant and anti-inflammatory compound. Previous studies have demonstrated that curcumin suppresses pro-inflammatory cytokine production... -
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- Clinical features and treatment outcomes of Hodgkin lymphoma: A retrospective review in a Malaysian tertiary hospital
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Boo YL, Ting HS, Yap DF, Toh SG, Lim SM
- KMID: 2459387
- Blood Res.
- 2019 Sep;54(3):210-217.
- doi: 10.5045/br.2019.54.3.210
BACKGROUND: Classical Hodgkin lymphoma (cHL) is a clinicopathologically unique, aggressive lymphoma arising from germinal center B-cells and is one of the most curable hematological malignancies. This study aimed to determine... -
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- Follicular Bronchiolitis Mimicking Lung Cancer in a Patient with Primary Sjögren's Syndrome
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Shin S, Ha YJ, Kang EH, Song YW, Lee YJ
- KMID: 2451513
- J Rheum Dis.
- 2019 Jul;26(3):206-210.
- doi: 10.4078/jrd.2019.26.3.206
Follicular bronchiolitis (FB) is an uncommon pulmonary lymphoproliferative disorder that is characterized by the presence of peribronchiolar hyperplastic lymphoid follicles with reactive germinal centers. FB could be associated with systemic... -
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- Respiratory Syncytial Virus Fusion Protein-encoding DNA Vaccine Is Less Effective in Conferring Protection against Inflammatory Disease than a Virus-like Particle Platform
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Kwon YM, Hwang HS, Lee YT, Kim KH, Lee Y, Kim MC, Lee YN, Quan FS, Moore ML, Kang SM
- KMID: 2450203
- Immune Netw.
- 2019 Jun;19(3):e18.
- doi: 10.4110/in.2019.19.e18
Formalin-inactivated respiratory syncytial virus (RSV) vaccination causes vaccine-enhanced disease (VED) after RSV infection. It is considered that vaccine platforms enabling endogenous synthesis of RSV immunogens would induce favorable immune responses... -
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- Histopathological and microbiological findings in buffalo chronic mastitis: evidence of tertiary lymphoid structures
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Restucci B, Dipineto L, Martano M, Balestrieri A, Ciccarelli D, Russo TP, Varriale L, Maiolino P
- KMID: 2448712
- J Vet Sci.
- 2019 May;20(3):e28.
- doi: 10.4142/jvs.2019.20.e28
Buffalo mastitis is an important economic problem in southern Italy, causing qualitative/quantitative alterations in milk and resulting in economic losses due to the sub-clinical course and chronic evolution. We investigated... -
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- Pulmonary Nodular Lymphoid Hyperplasia with Mass-Formation: Clinicopathologic Characteristics of Nine Cases and Review of the Literature
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Sim J, Koh HH, Choi S, Chu J, Kim TS, Kim H, Han J
- KMID: 2417804
- J Pathol Transl Med.
- 2018 Jul;52(4):211-218.
- doi: 10.4132/jptm.2018.04.27
BACKGROUND: Pulmonary nodular lymphoid hyperplasia (PNLH) is a non-neoplastic pulmonary lymphoid disorder that can be mistaken for malignancy on radiography. Herein, we present nine cases of PNLH, emphasizing clinicoradiological findings... -
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- MicroRNA-mediated Regulation of the Development and Functions of Follicular Helper T cells
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Lee J, Park H, Eom J, Kang SG
- KMID: 2410158
- Immune Netw.
- 2018 Apr;18(2):e7.
- doi: 10.4110/in.2018.18.e7
The germinal center reaction is a key event of humoral immunity, providing long-lived immunological memory. Follicular helper T (T(FH)) cells are a specialized subset of CD4⺠T cells located in... -
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- Interleukin-17 Enhances Germinal Center Formation and Immunoglobulin G1 Production in Mice
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Lee J, Lee SY, Kang CM, Jhun JY, Kim JH, Cho ML, Park SH, Kim HY, Kwok SK
- KMID: 2394342
- J Rheum Dis.
- 2017 Oct;24(5):271-278.
- doi: 10.4078/jrd.2017.24.5.271
OBJECTIVE: Interleukin (IL)-17 is a pro-inflammatory cytokine that has pleiotropic effects on multiple target cells and thereby contributes to the development of immune-mediated inflammatory disorders. However, the role of IL-17... -
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- Twin Rectal Tonsils Mimicking Carcinoid or Mucosa-Associated Lymphoid Tissue Lymphoma
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Takehara M, Muguruma N, Kitamura S, Kimura T, Okamoto K, Miyamoto H, Bando Y, Takayama T
- KMID: 2394752
- Clin Endosc.
- 2017 Sep;50(5):500-503.
- doi: 10.5946/ce.2016.157
The rectal tonsil is a rare polypoid lesion exclusively found in the rectum and is considered a reactive proliferation of the lymphoid tissue. Although this lesion is benign, we recommend... -
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- Secondary Cutaneous Follicular B-Cell Lymphoma Associated with Erythematous Swelling on the Leg: A Case Report
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Kim DJ, Lee SK, Lee UH, Kim MS
- KMID: 2388337
- Korean J Dermatol.
- 2017 Jul;55(6):364-368.
Cutaneous follicular B-cell lymphoma (CFBCL) is defined as the neoplastic proliferation of germinal center cells confined to the skin. Secondary CFBCL demonstrates a more aggressive clinical course compared to the... -
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- Progressive Transformation of Germinal Centers in Presacral Space: MRI Findings and Literature Review
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Hwang ST, Sung DJ, Sim KC, Han NY, Park BJ, Kim MJ, Lee JH
- KMID: 2376271
- Investig Magn Reson Imaging.
- 2017 Mar;21(1):56-60.
- doi: 10.13104/imri.2017.21.1.56
Progressive transformation of germinal centers (PTGC) is an atypical feature seen in lymph nodes with unknown pathogenesis. PTGC most commonly presents in adolescent and young adult males as solitary painless... -
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- Enforced Expression of CXCR5 Drives T Follicular Regulatory-Like Features in Foxp3⺠T Cells
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Kim YU, Kim BS, Lim H, Wetsel RA, Chung Y
- KMID: 2375032
- Biomol Ther.
- 2017 Mar;25(2):130-139.
- doi: 10.4062/biomolther.2016.075
CXCR5⺠T follicular helper (Tfh) cells are associated with aberrant autoantibody production in patients with antibody-mediated autoimmune diseases including lupus. Follicular regulatory T (Tfr) cells expressing CXCR5 and Bcl6 have... -
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- Case of Follicular Bronchiolitis in Rheumatoid Arthritis
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Lee JH, Choi M, Oh SS, Choi MR, Yang HJ, Lee KM, Choi KH
- KMID: 2364694
- J Rheum Dis.
- 2016 Dec;23(6):392-395.
- doi: 10.4078/jrd.2016.23.6.392
Follicular bronchiolitis is an uncommon bronchiolar disorder that is characterized by the presence of hyperplastic lymphoid follicles with reactive germinal centers. The condition is associated with connective tissue diseases such... -
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- Potential of Cells and Cytokines/Chemokines to Regulate Tertiary Lymphoid Structures in Human Diseases
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Jing F, Choi EY
- KMID: 2355020
- Immune Netw.
- 2016 Oct;16(5):271-280.
- doi: 10.4110/in.2016.16.5.271
Tertiary lymphoid structures (TLS) are ectopic lymphoid tissues involved in chronic inflammation, autoimmune diseases, transplant rejection and cancer. They exhibit almost all the characteristics of secondary lymphoid organs (SLO), which... -
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- Follicular Helper T (Tfh) Cells in Autoimmune Diseases and Allograft Rejection
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Jeon YH, Choi YS
- KMID: 2349883
- Immune Netw.
- 2016 Aug;16(4):219-232.
- doi: 10.4110/in.2016.16.4.219
Production of high affinity antibodies for antigens is a critical component for the immune system to fight off infectious pathogens. However, it could be detrimental to our body when the... -
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- Blockade of STAT3 in T Cells Inhibits Germinal Center Reactions against Intranasal Allergens
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Choi G, Chung Y
- KMID: 2164216
- Biomol Ther.
- 2016 May;24(3):244-251.
- doi: 10.4062/biomolther.2015.160
Understanding the developmental mechanisms of humoral immunity against intranasal antigens is essential for the development of therapeutic approaches against air-borne pathogens as well as allergen-induced pulmonary inflammation. Follicular helper T... -
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- The Significance of Ectopic Germinal Centers in the Minor Salivary Gland of Patients with Sjogren's Syndrome
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Lee KE, Kang JH, Yim YR, Kim JE, Lee JW, Wen L, Park DJ, Kim TJ, Park YW, Yoon KC, Lee JS, Lee SS
- KMID: 2360041
- J Korean Med Sci.
- 2016 Feb;31(2):190-195.
- doi: 10.3346/jkms.2016.31.2.190
We investigated the clinical and biological significance of germinal centers (GC) present in the minor salivary glands of patients with Sjogren's syndrome (SS). Minor salivary gland tissue biopsies from 93... -
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