- Regulation and Function of the Peg3 Imprinted Domain
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He H, Kim J
- KMID: 2009097
- Genomics Inform.
- 2014 Sep;12(3):105-113.
- doi: 10.5808/GI.2014.12.3.105
A subset of mammalian genes differ functionally between two alleles due to genomic imprinting, and seven such genes (Peg3, Usp29, APeg3, Zfp264, Zim1, Zim2, Zim3) are localized within the 500-kb... -
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- Transcriptional Profiles of Imprinted Genes in Human Embryonic Stem Cells During In vitro Differentiation
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Park SW, Do HS, Kim D, Ko JY, Lee SH, Han YM
- KMID: 1974598
- Int J Stem Cells.
- 2014 Nov;7(2):108-117.
- doi: 10.15283/ijsc.2014.7.2.108
BACKGROUND AND OBJECTIVES: Genomic imprinting is an inheritance phenomenon by which a subset of genes are expressed from one allele of two homologous chromosomes in a parent of origin-specific manner.... -
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- Three Cases of Russell-Silver Syndrome in One of Twins Conceived by In Vitro Fertilization
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Cho HJ, Song ES, Kim YH, Song TB, Choi YY
- KMID: 1472013
- Korean J Perinatol.
- 2009 Sep;20(3):266-272.
In vitro fertilization (IVF) is a main option for the infertility treatment and its major concerns are the risk of multiple pregnancy, preterm delivery, intrauterine growth retardation (IUGR), and congenital... -
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- Alteration of Genomic Imprinting Status of Human Parthenogenetic Induced Pluripotent Stem Cells during Neural Lineage Differentiation
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Lee HJ, Choi NY, Lee SW, Lee Y, Ko K, Kim GJ, Hwang HS, Ko K
- KMID: 2447222
- Int J Stem Cells.
- 2019 Mar;12(1):31-42.
- doi: 10.15283/ijsc18084
BACKGROUND AND OBJECTIVES: Genomic imprinting modulates growth and development in mammals and is associated with genetic disorders. Although uniparental embryonic stem cells have been used to study genomic imprinting, there... -
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- Frequent Biallelic Expression of Insulin-like Growth Factor II (IGF2) in Gynogenetic Ovarian Teratomas: Uncoupling of H19 and IGF2 Imprinting
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Chang SI
- KMID: 1538084
- J Genet Med.
- 1998 Mar;2(1):41-48.
Human uniparental gestations such as gynogenetic ovarian teratomas provide a model to evaluate the integrity of parent-specific gene expression - i.e. imprinting - in the absence of a complementary parental... -
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- Single Nucleotide Polymorphisms of a 16 kb Region on Human Chromosome 11p15.5 that Includes the H19 Gene
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Park MH, Ku HJ, Lee HJ, Kim KJ, Park C, Oh B, Kimm KC, Lee JY
- KMID: 1572676
- Genomics Inform.
- 2005 Sep;3(3):74-79.
The H19 gene, located at human chromosome 11p15.5, is imprinted in most normal human tissues. However, imprinting is often lost in tumors suggesting H19 is a putative tumor suppressor. We... -
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- Correlation between Chromosome Abnormalities and Genomic Imprinting in Developing Human 2) Independent Expression of Imprinted Genes, H19 and Insulin-like growth factor II (IGF2), in Androgenetic Hydatidiform Moles
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Chang SI, Choi BH, Lee TS, Kim DK, Lee IH
- KMID: 2092662
- Korean J Anat.
- 1998 Aug;31(4):611-617.
Human uniparental gestations such as androgenetic hydatidiform moles provide a model to evaluate the integrity of parent-specific gene expression,-i.e, genomic imprinting,- in the absence of a complementary parental genetic contribution.... -
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- Epigenetic Alterations and Loss of Imprinting in Colorectal Cancer
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Kim JW
- KMID: 2101396
- J Korean Soc Coloproctol.
- 2005 Jun;21(3):181-190.
Two forms of genomic instability have been described in colorectal cancer: chromosomal (CIN) and microsatellite instability (MIN). Colorectal cancer has been considered to progress through one of these two major... -
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- Genetic syndromes associated with overgrowth in childhood
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Ko JM
- KMID: 2266359
- Ann Pediatr Endocrinol Metab.
- 2013 Sep;18(3):101-105.
- doi: 10.6065/apem.2013.18.3.101
Overgrowth syndromes comprise a diverse group of conditions with unique clinical, behavioral and molecular genetic features. While considerable overlap in presentation sometimes exists, advances in identification of the precise etiology... -
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- Study of Genetic Imprinting on 3 Cases of Insulin-Dependent Diabetes Mellitus Developed in Early Infantile Period
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Song SM, Kim JS, Oh MR, Yang SW, Han HK, Jin DK
- KMID: 2193876
- J Korean Soc Pediatr Endocrinol.
- 1998 Nov;3(2):213-218.
Infantile onset diabetes mellitus(especially, neonatal diabetes) is rare disorder and may be transient or permanent. Most patients are full-term but small-for-date infants and typical symptoms occur within the first 4-6... -
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- Epigenetics in Head and Neck Cancer
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Park IS
- KMID: 2277106
- Korean J Otorhinolaryngol-Head Neck Surg.
- 2009 Dec;52(12):943-948.
- doi: 10.3342/kjorl-hns.2009.52.12.943
While genetic alterations in head and neck cancer have long been documented, the appreciation of epigenetic changes is more recent. Epigenetics of head and neck cancer becomes an area of... -
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- The Effect of Parental Imprinting on the INS-IGF2 Locus of Korean Type I Diabetic Patients
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Kim HS, Lee DW, Lee SJ, Choi BH, Chang SI, Yoon HD, Lee IK
- KMID: 759564
- Korean J Intern Med.
- 2001 Dec;16(4):223-229.
BACKGROUND: Insulin-dependent diabetes mellitus (IDDM) is caused by the autoimmune destruction of pancreatic beta-cells. Susceptibility to IDDM appears to depend on more than one genetic locus. Evidence of a genetic... -
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- Understanding of epigenetics and DNA methylation
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Oh JH, Kwon YD, Yoon BW, Choi BJ
- KMID: 2118379
- J Korean Assoc Maxillofac Plast Reconstr Surg.
- 2008 May;30(3):302-309.
Epigenetic is usually referring to heritable traits that do not involve changes to the underlying DNA sequence. DNA methylation is known to serve as cellular memory, and is one... -
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- Systematic review of the clinical and genetic aspects of Prader-Willi syndrome
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Jin DK
- KMID: 2073622
- Korean J Pediatr.
- 2011 Feb;54(2):55-63.
- doi: 10.3345/kjp.2011.54.2.55
Prader-Willi syndrome (PWS) is a complex multisystem genetic disorder that is caused by the lack of expression of paternally inherited imprinted genes on chromosome 15q11-q13. This syndrome has a characteristic... -
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- Evolutionary Hypotheses of Mental Disorder and Their Limitations
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Park H
- KMID: 2465997
- J Korean Soc Biol Ther Psychiatry.
- 2019 Oct;25(3):165-182.
- doi: 10.0000/jksbtp.2019.25.3.165
Like the body of Hominin, mind is the result of natural selection. Therefore, an evolutionary approach in the biological aspects is essential for an intrinsic understanding of mental disorders. However,... -
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- Methylation Patterns of Small Nuclear Ribonucleoprotein Polypeptide N (SNRPN) Related to the Germ Cell Differentiation of Human Germ Cell Tumors
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Jun SY, Kim KR, Choi J, Ro JY
- KMID: 1521691
- Korean J Pathol.
- 2007 Feb;41(1):21-29.
BACKGROUND: The histogenesis and interrelationship of the various types of germ cell tumors (GCTs) have been proposed. Dysgerminoma/seminoma (D/S) is a primitive GCT that has not acquired the potential for... -
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- Cancer Epigenetics
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Chang DK
- KMID: 1113291
- Korean J Gastroenterol.
- 2004 Jul;44(1):1-12.
Knowledge regarding molecular events of cancer development has been rapidly accumulated during the last decade. The discovery of tumor suppressor gene-silencing by aberrant promoter CpG island hypermethylation and histone-directed chromatin... -
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- The Molecular Nature of Very Small Embryonic-Like Stem Cells in Adult Tissues
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Kim Y, Jeong J, Kang H, Lim J, Heo J, Ratajczak , Ratajczak , Shin DM
- KMID: 1974592
- Int J Stem Cells.
- 2014 Nov;7(2):55-62.
- doi: 10.15283/ijsc.2014.7.2.55
Pluripotent stem cells (PSCs) have been considered as the most important cells in regenerative medicine as they are able to differentiate into all types of cells in the human body.... -
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- No influence of parental origin of intact X chromosome and/or Y chromosome sequences on three-year height response to growth hormone therapy in Turner syndrome
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Lee HJ, Jung HW, Lee GM, Kim HY, Kim JH, Lee SH, Kim JH, Lee YA, Shin CH, Yang SW
- KMID: 2134079
- Ann Pediatr Endocrinol Metab.
- 2014 Sep;19(3):127-134.
- doi: 10.6065/apem.2014.19.3.127
PURPOSE: Whether parental origin of the intact X chromosome and/or the presence of Y chromosome sequences (Yseq) play a role in three-year height response to growth hormone (GH) were investigated. METHODS:... -
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- Clinical and Genetic Characteristics of Prader-Willi Syndrome and Angelman Syndrome
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Kim JH, Yum MS, Choi HW, Lee EH, You SJ, Ko TS, Yoo HW
- KMID: 1442115
- J Korean Child Neurol Soc.
- 2011 Aug;19(2):150-157.
PURPOSE: Two different disorders, Prader-Willi syndrome (PWS) and Angelman syndrome (AS) are caused by the deletion of 15q11-13 or the maternal/paternal uniparental disomy of chromosome 15 (mUPD(15)/pUPD(15)) through the genomic... -
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