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Lack of Toll-like Receptor 4 and 2 Polymorphisms in Korean Patients with Bacteremia

Yoon HJ, Choi JY, Kim CO, Park YS, Kim MS, Kim YK, Shin SY, Kim JM, Song YG

Toll-like receptors (TLRs) are pattern-recognition receptors that are important in innate immune responses to bacterial infection. The purpose of this study is to describe the prevalence of TLRs genetic variations...
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Relationship Between the Extent of Chromosomal Losses and the Pattern of CpG Methylation in Gastric Carcinomas

Hong SJ, Kim YH, Choi YD, Min KO, Choi SW, Rhyu MG

The extent of unilateral chromosomal losses and the presence of microsatellite instability (MSI) have been classified into high-risk (high- and baseline-level loss) and low-risk (low-level loss and MSI) stem-line genotypes...
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Alpha-Adducin Gly460Trp Polymorphism and Essential Hypertension in Korea

Shin MH, Chung EK, Kim HN, Park KS, Nam HS, Kweon SS, Choi JS

Previous studies have suggested that the Gly460Trp polymorphism of the alpha-adducin gene (ADD-1) is associated with salt sensitivity and primary hypertension. The results of linkage or association studies of ADD-1...
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Hypermethylation of Tumor-related Genes in Genitourinary Cancer Cell Lines

Chung WB, Hong SH, Kim JA, Sohn YK, Kim BW, Kim JW

Hypermethylation of CpG island is a common mechanism for the inactivation of tumor-related genes. In the present study, we analyzed 13 genitourinary cancer cell lines for aberrant DNA methylation of...
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Effectiveness of Real-Time Quantitative PCR Compare to Repeat PCR for the Diagnosis of Charcot-Marie-Tooth Type 1A and Hereditary Neuropathy with Liability to Pressure Palsies

Choi JR, Lee WH, Sunwoo IN, Lee EK, Lee CH, Lim JB

The majority of cases of Charcot-Marie-Tooth type 1A (CMT1A) and of hereditary neuropathy with a liability to pressure palsies (HNPP) are the result of heterozygosity for the duplication or deletion...
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