- Comparison of Consensus Sequences and Ancestor Sequences of HIV-1 nef and vif Genes for Development of Korean-Specfic HIV-1 Vaccine
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Park CS, Kim MS, Yi HA, Lee KM, Kim SS, Lee SD, Lee CH
- KMID: 2055038
- J Bacteriol Virol.
- 2006 Dec;36(4):287-292.
- doi: 10.4167/jbv.2006.36.4.287
There have been attempts to use consensus sequences or ancestor sequences for development vaccines against viruses with high diversity and variation. In this study, we generated and compared consensus sequences... -
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- Mutational Analysis of ASPP1 and ASPP2 Genes, a p53-related Gene, in Gastric and Cololorectal Cancers with Microsatellite Instability
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Park SW, An CH, Kim SS, Yoo NJ, Lee SH
- KMID: 2284204
- Gut Liver.
- 2010 Jun;4(2):292-293.
No abstract available. -
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- Informative Gene Selection Method in Tumor Classification
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Lee HS, Park JH
- KMID: 1974007
- Genomics Inform.
- 2004 Mar;2(1):19-29.
Gene expression profiles may offer more information than morphology and provide an alternative to morphology- based tumor classification systems. Informative gene selection is finding gene subsets that are able to... -
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- Expression of Osteoclastogenesis-related Genes in Rheumatoid Arthritis Synovial Macrophages
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Ji JD, Kim TH, Lee B, Choi SJ, Lee YH, Song GG
- KMID: 2223176
- J Rheum Dis.
- 2011 Mar;18(1):11-18.
- doi: 10.4078/jrd.2011.18.1.11
OBJECTIVE: To examine the mechanism for the inhibited differentiation of osteoclasts in rheumatoid arthritis synovial CD14+ osteoclast precursors, the different expressions of the osteoclastogenesis-related genes in rheumatoid arthritis (RA) synovial... -
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- Systems biology approaches in asthma pharmacogenomics study
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Park HW
- KMID: 1803538
- Allergy Asthma Respir Dis.
- 2014 Nov;2(5):326-331.
- doi: 10.4168/aard.2014.2.5.326
The response to drug treatment in asthma is a complex trait and is markedly variable even in patients with apparently similar clinical features. Pharmacogenomics is a study of variations of... -
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- Gene Expression Regulation by Agonist-Independent Constitutive Signaling of Melanocortin-1 Receptor
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Seong I, Kim J
- KMID: 2169425
- Endocrinol Metab.
- 2014 Jun;29(2):179-184.
- doi: 10.3803/EnM.2014.29.2.179
BACKGROUND: Melanocortin-1 receptor (Mc1r), a key signaling receptor for melanogenesis, has been reported to mediate migration of B16F10 melanoma cells. Interestingly, this activity appears to be a part of the... -
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- A two-component signal transduction system contributes to the virulence of Riemerella anatipestifer
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Wang Q, Chen M, Zhang W
- KMID: 2407625
- J Vet Sci.
- 2018 Mar;19(2):260-270.
- doi: 10.4142/jvs.2018.19.2.260
Similar to other studies of bacterial pathogens, current studies of the pathogenesis of Riemerella anatipestifer (RA) are focused mainly on in vitro culture conditions. To elucidate further the pathogenesis of... -
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- A study on the expression of immediate-early genes by light stimuli in the rat suprachiasmatic nucleus using differential display
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Park HT, Kim WI, Kang EK, Park JK, Bae KW
- KMID: 2040090
- Korean J Anat.
- 1999 Aug;32(4):451-457.
The hypothalamic suprachiasmatic nucleus (SCN) of the mammal is the circadian pacemaker responsible for generation of circadian rhythms. Several immediate-early genes are expressed in the SCN by light stimuli which... -
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- Genetic Hearing Loss and Gene Therapy
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Carpena NT, Lee MY
- KMID: 2439210
- Genomics Inform.
- 2018 Dec;16(4):e20.
- doi: 10.5808/GI.2018.16.4.e20
Genetic hearing loss crosses almost all the categories of hearing loss which includes the following: conductive, sensory, and neural; syndromic and nonsyndromic; congenital, progressive, and adult onset; high-frequency, low-frequency, or... -
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- Complete Sequence of the Mitochondrial Genome of Spirometra ranarum: Comparison with S. erinaceieuropaei and S. decipiens
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Jeon HK, Park H, Lee D, Choe S, Kang Y, Bia MM, Lee SH, Eom KS
- KMID: 2441608
- Korean J Parasitol.
- 2019 Feb;57(1):55-60.
- doi: 10.3347/kjp.2019.57.1.55
This study was undertaken to determine the complete mitochondrial DNA sequence and structure of the mitochondrial genome of Spirometra ranarum, and to compare it with those of S. erinaceieuropaei and... -
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- Study of the Gene Expressions in Rheumatoid Arthritis Synovial Macrophages Using Network Analysis
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Ji JD, Kim TH, Lee B, Choi SJ, Lee YH, Song GG
- KMID: 2391936
- J Rheum Dis.
- 2011 Jun;18(2):101-109.
OBJECTIVE: We wanted to investigate the mechanisms that could account for the pathogenesis of rheumatoid arthritis, so we examined the different expressions of the genes in rheumatoid arthritis (RA) synovial... -
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- Relationship Between the Level of Methicillin Resistance and mecA, mecI, femA Genes Genes in Staphylococci
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Lee HK, Lee EJ, Pahk YJ, Kim BK, Kang MW, Shim SI
- KMID: 1557268
- Korean J Infect Dis.
- 1998 Feb;30(1):36-44.
BACKGROUND: About 60~70% of hospital isolates of staphylococci are resistant to methicillin. The level of resistance varies from low to high depending upon the genetic background of the strains. The... -
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- Tumor targeted gene therapy
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Kang JH
- KMID: 1512522
- Nucl Med Mol Imaging.
- 2006 Oct;40(5):237-242.
Knowledge of molecular mechanisms governing malignant transformation brings new opportunities for therapeutic intervention against cancer using novel approaches. One of them is gene therapy based on the transfer of genetic... -
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- Difference of Gene Expression in Venous Malformation
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Kim TK, Oh EJ, Cho BC, Chung HY
- KMID: 2322376
- J Korean Soc Plast Reconstr Surg.
- 2007 Nov;34(6):671-678.
PURPOSE: Venous malformation(VM) which often causes pain and discomfort is the most common type of vascular malformations. Although it is presented with disfigured appearance and associated soft tissue or skeletal... -
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- Molecular Application in Psychiatry
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Choi IG
- KMID: 1899244
- J Korean Soc Biol Psychiatry.
- 2000 Nov;7(2):115-122.
The development of molecular biology has brought many changes in psychiatry. Molecular biology makes us possible to know the cause of mental disorders that provide the way to prevent the... -
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- Expression of doc-1 in Pregnant Uterus of the Mouse
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Cheon YP
- KMID: 1566326
- Korean J Fertil Steril.
- 2002 Dec;29(4):295-302.
Uterine cells carry out proliferation and differentiation for preparation the embryonic implantation during pregnancy. Therefore regulation of the cell proliferation is an essential step for uterine preparation, but there is... -
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- Analysis of gene expression during odontogenic differentiation of cultured human dental pulp cells
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Seo MS, Hwang KG, Kim H, Baek SH
- KMID: 1995653
- Restor Dent Endod.
- 2012 Aug;37(3):142-148.
- doi: 10.5395/rde.2012.37.3.142
OBJECTIVES: We analyzed gene-expression profiles after 14 day odontogenic induction of human dental pulp cells (DPCs) using a DNA microarray and sought candidate genes possibly associated with mineralization. MATERIALS AND METHODS:... -
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- Exploring the Key Genes and Pathways of Osteoarthritis in Knee Cartilage in a Rat Model Using Gene Expression Profiling
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Ren YM, Zhao X, Yang T, Duan YH, Sun YB, Zhao WJ, Tian MQ
- KMID: 2415535
- Yonsei Med J.
- 2018 Aug;59(6):760-768.
- doi: 10.3349/ymj.2018.59.6.760
PURPOSE: To compare differentially expressed genes (DEGs) mediating osteoarthritis (OA) in knee cartilage and in normal knee cartilage in a rat model of OA and to identify their impact on... -
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- Molecular Marker Related to Fruitbody Color of Flammulina velutipes
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Kong WS, You CH, Yoo YB, Kim GH, Kim KH
- KMID: 2312424
- Mycobiology.
- 2004 Mar;32(1):6-10.
White and brown strains of Flammulina velutipes were inter-crossed. All F1 showed light-brown fruitbody, suggesting that a gene for the brown fruitbody was incompletely dominant against the white one. And... -
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- Integrated Analysis of MicroRNA and mRNA Expression Profiles in Rheumatoid Arthritis Synovial Monocytes
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Ji JD, Kim TH, Lee B, Na KS, Choi SJ, Lee YH, Song GG
- KMID: 2223128
- J Rheum Dis.
- 2011 Dec;18(4):253-263.
- doi: 10.4078/jrd.2011.18.4.253
OBJECTIVE: MicroRNAs (miRNAs) play important roles in many biological processes and recent studies have provided growing evidences that miRNA dysregulation might play important roles in the pathogenesis of rheumatoid arthritis... -
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