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Regulation of p53 Genes by Ferritin Light Chain: Preliminary Study

Yi SY

No abstract available in English.
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Prognostic Significance of Immunohistochemical Expression of p53 Gene Product in Operable Breast Cancer

Song HS, Do YR, Kang SH, Jeong KY, Kim YS

  • KMID: 2166050
  • Cancer Res Treat.
  • 2006 Dec;38(4):218-223.
PURPOSE: The aim of this study was to investigate the prognostic significance of the expression of p53 gene product in operable invasive breast cancer by performing immunohistochemical analysis. MATERIALS AND...
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p53 Gene Mutation in Gastric Cancer Tissue

Ku KB, Park SH, Cheong HY, Yu W, Lee MH

  • KMID: 1565012
  • J Korean Gastric Cancer Assoc.
  • 2006 Dec;6(4):214-220.
PURPOSE: p53 is one of the most commonly mutated genes in human tumors. The aim of this study was to analyze p53 mutation in gastric cancer and its correlations with...
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Expression of the Matrix Metalloproteinase-2/9 and Tissue Inhibitor of Metalloproteinase-2 Proteins with Heterozygosity of p53 Gene in Thyroid Tumors

Kim SB, Rho YS, Ahn HY, Cho SJ, Shin HS

  • KMID: 2037122
  • Korean J Otolaryngol-Head Neck Surg.
  • 2005 Feb;48(2):225-233.
BACKGROUND AND OBJECTIVES: Mutations or overexpression of the p53 gene is believed to play an important role in the progression of various human malignant tumors. The type IV collagenase (matrix...
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The Combined Effect of Gamma Knife Irradiation and p53 Gene Transfection in Human Malignant Glioma Cell Lines

Kim JE, Paek SH, Kim DG, Chung HT, Kim YY, Jung HW

  • KMID: 1817828
  • J Korean Neurosurg Soc.
  • 2005 Jan;37(1):48-53.
OBJECTIVE: The purpose of this study is to elucidate in vitro responses to combined gamma knife irradiation and p53 gene transfection on human malignant glioma cell lines. METHODS: Two malignant...
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Human Papillomavirus Type 16, 18, and 33 Infection in Adenocarcinoma of the Uterine Cervix: Analysis of the p53 Gene Mutation and the Clincopathologic Correlation

Suh KS, Cho SJ, Na SY, Noh HT, Nam SR

  • KMID: 2073839
  • Korean J Pathol.
  • 2004 Oct;38(5):295-300.
BACKGROUND: Current evidence implicates specific types of the human papillomavirus (HPV) are involved in the development of cervical cancer. In HPV-negative cervical carcinomas, p53 mutation is thought to be a...
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The Property of p53 Gene in Cell Lines of Squamous Cell Carcinoma

Jin Y, Moon YS, Jeong HS, Jang SI, Choi IJ

  • KMID: 2224509
  • Korean J Anat.
  • 2004 Jun;37(3):293-299.
The mutation of p53 tumor suppressor gene is the most common genetic variation of primary malignant tumors. The occurrence, progression and reaction for medical management of cancers can be different...
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Clinical Significance of p53 Gene and nm23 Gene Expression in Esophageal Cancer

Park K, Lee JH, Sa YJ, Jin U, Kwon JB, Park JG, Lee SH, Kwak MS

  • KMID: 1878302
  • Korean J Thorac Cardiovasc Surg.
  • 2004 Mar;37(3):261-266.
BACKGROUND: Although significant progress has been made in the surgical treatment of esophageal carcinoma as well as in the detection of early stage esophageal carcinoma by diagnostic techniques, the prognosis...
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p53 Gene Mutation, Tumor p53 Protein Overexpression, and Serum Anti-p53 Antibody in Patients with Gastric Cancer

Bong JG, Lee MH, Song KE, Kim T, Yu W

  • KMID: 2372735
  • J Korean Gastric Cancer Assoc.
  • 2003 Dec;3(4):206-213.
PURPOSE: The clinical implication of p53 mutation in gastric cancer is still unclear, as shown by the discordant results that continue to be reported in the literature. MATENRIALS AND METHODS: To...
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Growth Suppression and Induction of Chemosensitivity in Human Gallbladder Epithelial Carcinoma Cells (GBCE) by Adenovirus-Mediated Transfer of the Wild-type p53 Gene

Kim SB, Kim MH, Lee SK, Kim TW, Suh C, Shin JS, Park JS, Kim ES, Gong G, Lee JS, Kim WK, Kim SH

  • KMID: 1972874
  • Cancer Res Treat.
  • 2003 Dec;35(6):521-527.
PURPOSE: Mutations in the p53 gene are reported in 50~90% of gallbladder and bile duct cancer, and have been implicated in chemoresistance. We undertook this study to determine whether the...
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Genetic Instability and Mutations of Mismatch Repair (MMR) and p53 Gene in Colorectal Cancers with Multiple Polyps and Sporadic Colorectal Cancers

Chun SW, Chang SK

  • KMID: 2334284
  • J Korean Soc Coloproctol.
  • 2002 Dec;18(6):353-362.
PURPOSE: General conceptions of carcinogenic mechanisms by recent reports are ras-p53 gene pathway in sporadic colorectal cancers (SCC), MMR gene pathway in hereditary nonpolyposis colorectal cancer (HNPCC) and APC gene...
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Expression of C-MYC, C-RAS, C-ERB B-2 Oncogenes and P53 Gene in Hydatidiform Mole

Choi HS, Kim SM, Park CS

  • KMID: 1980217
  • Korean J Gynecol Oncol Colposc.
  • 2002 Dec;13(4):336-341.
OBJECTIVE: To date early predictors for the development of persistent gestational trophoblastic disease (PGTD) after evacuation of a complete hydatidiform mole were not known. The purpose of this study was...
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Mutation of p53 Gene and Infection of Human Papillomavirus in Oral and Oropharyngeal Carcinoma

Choi JS, Park SJ, Jo HC, Kim SY, Jung CW, Cho JS, Nam JH, Park CS

  • KMID: 2275952
  • Korean J Otolaryngol-Head Neck Surg.
  • 2002 Aug;45(8):796-804.
BACKGROUND AND OBJECTIVES: Oral and oropharyngeal squamous cell carcinomas (SCC) are diseases that are largely attributed to environmental exposure. Tobacco use and alcohol consumption are well-established risk factors. However, small...
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Analysis of p53 Gene Mutation in Basal Cell Carcinoma in Korean Patients

Oh CK, Lee JH, Lim JY, Kim SJ, Kim MB, Jang HS, Kwon KS

  • KMID: 2250821
  • Korean J Dermatol.
  • 2002 Jun;40(6):651-659.
BACKGROUND: There were few data on the gene mutations involved in the development of basal cell carcinoma(BCC) in Korean. OBJECTIVE: To gain insight into the role of p53 gene mutations of...
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In Vitro Effect of Liposome-mediated Combined p16 and p53 Gene Transfer to the Human Glioblastoma Cell Lines

Kim CH, Kwon JT, Min BK, Hwang SN, Hwang DY, Choi DY

  • KMID: 1955924
  • J Korean Neurosurg Soc.
  • 2002 Feb;31(2):152-160.
OBJECTIVE: To overcome the limitations of the single gene transfer, the authors present the results of wild-type p16 and p53 combined genes transfer in vitro to the U251MG and U373MG...
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Adenovirus and Lipofectin Mediated p53 Gene Transfection Efficiency in Human Cervical Cancer Cell Lines and Xenografted Nude Mouse

Yeo KA, Jung JE, Lee HY, Lee BH, Kim TH, Cheung BS, Rho MS, Lee JM, Namkoong S, Park YS, Kim CK, Ahn WS

  • KMID: 2262277
  • Korean J Obstet Gynecol.
  • 2001 Jun;44(6):1137-1144.
BACKGROUND: The classical treatment of the cervical cancer is surgery, radiotherapy, chemotherapy. Even though the improvement of treatment successful rate, conventional therapy has some limitations. Recent cutting edge of cancer...
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p53 Gene Mutation by Direct DNA Sequencing Predicts Poor Survival in Patients with Stomach Cancer

Kim TW, Lee KH, Lee JH, Kang YK, Lee JS, Kim SH, Im SW, Kim JS, Kim J, Kim WK

  • KMID: 1815300
  • J Korean Cancer Assoc.
  • 2000 Oct;32(5):835-843.
No abstract available.
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MICROSATELLITE INSTABILITY AND p53 GENE MUTATION IN ORAL SQUAMOUS CELL CARCINOMA

Choi TH, Chung WB, Hong SH, Kim JA, Na SO, Jang HJ, Sohn YK, Kim CS, Kim JW

  • KMID: 2005996
  • J Korean Assoc Oral Maxillofac Surg.
  • 2000 Aug;26(4):337-344.
Germ-line mutations at DNA repair loci confer susceptibility to colon cancer in hereditary non-polypopsis colorectal cancer. Somatic loss of DNA mismatch repair gene has been reported in a large variety...
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Modulation of Telomerase Activity by p53 Gene in KATO - III Gastric Carcinoma Cell Line

Kim SY, Cho KS, Park JK, Kim YI, Yoon HJ

  • KMID: 2175121
  • J Korean Cancer Assoc.
  • 1999 Dec;31(6):1112-1119.
PURPOSE: Alteration of p53 and telomerase activity may be responsible for gastric carcino- genesis. In this study, we tried to observe modulation of telomerase activity by wild type p53 in...
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K-ras and p53 gene mutation in endometrial hyperplasia and adenocarcinoma

Kim HO, Lee JH, Lee IW, Han SA, Park MJ, Cho HD, Kim IS, Kim CH

  • KMID: 2261537
  • Korean J Obstet Gynecol.
  • 1999 Oct;42(10):2192-2198.
Endometrial adenocarcinoma is the third common malignancy of female genital tract and categorized as estrogen-dependent tumor (type I) or not (type II). Type II endometrial adenocarcinoma more frequently occurs...
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