- Interpretation of the hygiene and microflora hypothesis for allergic diseases through epigenetic epidemiology
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Bae JM
- KMID: 2438461
- Epidemiol Health.
- 2018;40:e2018006.
- doi: 10.4178/epih.e2018006
The hygiene hypothesis (HH) proposed by Strachan in 1989 was expanded to explain the inverse association between the occurrence of allergy disorders and the risk of infectious diseases and parasite... -
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- Suicide : Gene-Environment Interaction
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Kim YK
- KMID: 2249836
- Korean J Biol Psychiatry.
- 2010 May;17(2):65-69.
Gene-environment interactions are important in pathogenesis of suicide or suicidal behavior. Twin and adoption studies and family studies show that genetic factors play a critical role in suicide or suicidal... -
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- Gene-Environment Interactions Should be Considered in Future Studies to Understand the Association Between Prenatal Folate Supplementation and Asthma Development
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Yu J
- KMID: 2130257
- Allergy Asthma Immunol Res.
- 2015 Nov;7(6):523-524.
- doi: 10.4168/aair.2015.7.6.523
No abstract available. -
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- Gene-Environment Interactions in Asthma: Genetic and Epigenetic Effects
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Lee JU, Kim JD, Park CS
- KMID: 2366325
- Yonsei Med J.
- 2015 Jul;56(4):877-886.
- doi: 10.3349/ymj.2015.56.4.877
Over the past three decades, a large number of genetic studies have been aimed at finding genetic variants associated with the risk of asthma, applying various genetic and genomic approaches... -
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- Depression and Gene-Environment Interaction
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Kim YK
- KMID: 2341819
- J Korean Neuropsychiatr Assoc.
- 2010 Nov;49(6):538-545.
Major depressive disorder (MDD) is a common disorder, widely distributed in the population, and usually associated with substantial symptom severity and role impairment. MDD is also a complex and heterogeneous... -
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- Age of Onset in Schizophrenia Spectrum Disorders: Complex Interactions between Genetic and Environmental Factors
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Mandelli L, Toscano E, Porcelli S, Fabbri C, Serretti A
- KMID: 2316623
- Psychiatry Investig.
- 2016 Mar;13(2):247-249.
- doi: 10.4306/pi.2016.13.2.247
In this study we evaluated the role of a candidate gene for major psychosis, Sialyltransferase (ST8SIA2), in the risk to develop a schizophrenia spectrum disorders, taking into account exposure to... -
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- Interaction of Apolipoprotein E epsilon4 and Education on Cognitive Decline in Korean Elders
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Kim JM, Shin IS, Kim SW, Yang SJ, Park SW, Shin HY, Yoon JS
- KMID: 1770033
- Korean J Biol Psychiatry.
- 2008 Feb;15(1):29-34.
OBJECTIVES: This study aimed to test potential modifying effects of education on the association between apolipoprotein E epsilon4 (Apo E4) and cognitive decline. METHODS: A community cohort(N=683) aged 65 or over... -
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- Interaction between Smoking and the STAB2 Gene in the Severity of Rheumatoid Arthritis
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Min JY, Min KB, Sung J, Cho SI
- KMID: 2166437
- Genomics Inform.
- 2009 Mar;7(1):20-25.
Rheumatoid arthritis (RA) is a chronic autoimmune disorder that is characterized by inflammation of the synovial tissue and deterioration of the joint and bone. A recent study reported a potential... -
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- Epigenetics and Psychiatric Disorders
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Oh D, Yang BH, Lee YS
- KMID: 2299915
- Korean J Biol Psychiatry.
- 2008 Nov;15(4):243-253.
In the post-genomic era, the mechanisms controlling activation of genes are thought to be more important. Gene-environment interactions are crucial in both development and treatment of psychiatric disorders as they... -
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- Effects of Genetic and Environmental Factors on the Depression in Early Adulthood
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Kim SK, Lee SI, Shin CJ, Son JW, Eom SY, Kim H
- KMID: 1770031
- Korean J Biol Psychiatry.
- 2008 Feb;15(1):14-22.
OBJECTIVES: The authors purposed to present data for explaining gene-environmental interaction causing depressive disorder by examining the effects of genetic factors related to the serotonin system and environmental factors such... -
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- Necessity of Epigenetic Epidemiology Studies on the Carcinogenesis of Lung Cancer in Never Smokers
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Bae JM
- KMID: 2424400
- J Prev Med Public Health.
- 2018 Sep;51(5):263-264.
- doi: 10.3961/jpmph.18.076
Based on epidemiological and genomic characteristics, lung cancer in never smokers (LCNS) is a different disease from lung cancer in smokers. Based on current research, the main risk factor for... -
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- Evolutionary Psychiatry I-Concept of Evolutionary Psychology and Evolutionary Psychopathology
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Park CJ, Kang UG
- KMID: 2419263
- J Korean Neuropsychiatr Assoc.
- 2018 May;57(2):157-172.
- doi: 10.4306/jknpa.2018.57.2.157
The evolutionary theory is applied to explain a multitude of natural and social phenomena. In medicine, evolutionary biology and psychology enables us to take perspectives beyond the biomedical paradigm of... -
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- Genetic Signatures of Asthma Exacerbation
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Park HW, Tantisira
- KMID: 2371719
- Allergy Asthma Immunol Res.
- 2017 May;9(3):191-199.
- doi: 10.4168/aair.2017.9.3.191
Asthma exacerbation (AE) usually denotes worsening of asthma symptoms that requires intense management to prevent further deterioration. AE has been reported to correlate with clinical and demographic factors, such as... -
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- Replication of Early B-cell Factor 1 (EBF1) Gene-by-psychosocial Stress Interaction Effects on Central Adiposity in a Korean Population
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Kim HJ, Min JY, Min KB
- KMID: 2356069
- J Prev Med Public Health.
- 2016 Sep;49(5):253-259.
- doi: 10.3961/jpmph.16.028
OBJECTIVES: Central obesity plays a major role in the development of many chronic diseases, including cardiovascular disease and cancer. Chronic stress may be involved in the pathophysiology of central obesity.... -
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- RORA Polymorphism Interacts with Childhood Maltreatment in Determining Anxiety Sensitivity by Sex: A Preliminary Study in Healthy Young Adults
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Min JA, Lee HJ, Lee SH, Park YM, Kang SG, Park YG, Chae JH
- KMID: 2396311
- Clin Psychopharmacol Neurosci.
- 2017 Nov;15(4):402-406.
- doi: 10.9758/cpn.2017.15.4.402
OBJECTIVE: Recent studies have reported associations of retinoid-related orphan receptor alpha (RORA) gene single nucleotide polymorphisms (SNPs) with depression and anxiety disorders. Based on these, we attempt to test whether... -
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- Association of Dietary Vitamin D and Calcium With Genetic Polymorphisms in Colorectal Neoplasia
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Park Y, Kim J
- KMID: 2171334
- J Cancer Prev.
- 2015 Jun;20(2):97-105.
- doi: 10.15430/JCP.2015.20.2.97
The incidence trends of colorectal cancer have varied over time, and there is wide geographical variation across the world. Regarding colorectal cancer, diverse modifiable environmental or intrinsic risk factors have... -
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- Breastfeeding Might Have Protective Effects on Atopy in Children With the CD14C-159T CT/CC Genotype
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Lee SY, Kang MJ, Kwon JW, Park KS, Hong SJ
- KMID: 2260318
- Allergy Asthma Immunol Res.
- 2013 Jul;5(4):239-241.
- doi: 10.4168/aair.2013.5.4.239
Breastfeeding is widely recommended to reduce risk of sensitization, eczema and asthma. However, the role of breastfeeding in prevention of allergic diseases is uncertain. We aimed to investigate whether the... -
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- Predicting Behavior Problems in Korean Preschoolers: Interactions of the SLC6A4 Gene and Maternal Negative Affectivity
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Ha J, Jun HJ, Shin H, Chung IJ, Park E, Min SK, Kim E
- KMID: 2456723
- Clin Psychopharmacol Neurosci.
- 2019 Mar;17(2):200-210.
- doi: 10.9758/cpn.2019.17.2.200
OBJECTIVE: This study aimed to investigate whether maternal negative affectivity (MNA) moderates the effect of genetic polymorphism of SLC6A4 on behavior problems in children. METHODS: Study participants comprised 143 preschoolers and... -
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- Interaction between Genetic Polymorphisms of CYP2E1 & NAT1 and Smoking in Lung Cancer Development (Preliminary report)
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Lee KM, Lee SJ, Park SK, Lee SY, Im HJ, Yoon KJ, Choi IM, Lee YJ, Kim SU, Choi H, Choi SH, Kim YW, Cho SH, Kang D
- KMID: 2007125
- J Korean Cancer Assoc.
- 2001 Feb;33(1):41-48.
PURPOSE: The interactive effects of genetic polymorphisms of cytochrome P4502E1 (CYP2E1) & N-acetyltransferase 1 (NAT1) and smoking on lung cancer development were evaluated in hospital based case-control study. MATERIALS AND METHODS:... -
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- Atopic Dermatitis
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Bieber T
- KMID: 2265381
- Ann Dermatol.
- 2010 May;22(2):125-137.
- doi: 10.5021/ad.2010.22.2.125
Atopic dermatitis (AD) is a chronic and relapsing disease affecting an increasing number of patients. Usually starting in early childhood, AD can be the initial step of the so-called atopic... -
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